Treadmill exercise suppresses nigrostriatal dopaminergic neuronal loss in 6-hydroxydopamine-induced Parkinson's rats

Exercise: a behavioral intervention to enhance brain health and plasticity

2002 • 2,571 citations

Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

2001 • 1,210 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Classic toxin-induced animal models of Parkinson?s disease: 6-OHDA and MPTP

2004 • 755 citations

Characterization of Behavioral and Neurodegenerative Changes Following Partial Lesions of the Nigrostriatal Dopamine System Induced by Intrastriatal 6-Hydroxydopamine in the Rat

1998 • 648 citations

Circulating Insulin-Like Growth Factor I Mediates the Protective Effects of Physical Exercise against Brain Insults of Different Etiology and Anatomy

2001 • 593 citations

Parkinson's disease: pathophysiology

1991 • 521 citations

Dopamine- or L-DOPA-induced neurotoxicity: The role of dopamine quinone formation and tyrosinase in a model of Parkinson’s disease

2003 • 500 citations

Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease

2003 • 401 citations

Physical activity and the risk of Parkinson disease

2005 • 357 citations

Effects of Exercise on Gene-Expression Profile in the Rat Hippocampus

2001 • 329 citations

Treadmill training with body weight support: Its effect on Parkinson's disease

2000 • 313 citations

Regulation of brain function by exercise

2003 • 268 citations

Neuroprotective effects of prior limb use in 6‐hydroxydopamine‐treated rats: possible role of GDNF

2003 • 246 citations

Tyrosine hydroxylase and Parkinson's disease

1998 • 245 citations

Environmental enrichment in adulthood eliminates neuronal death in experimental Parkinsonism

2004 • 236 citations

Striatal dopamine turnover during treadmill running in the rat: Relation to the speed of running

1994 • 222 citations

Surgical treatment for Parkinson's disease

2004 • 178 citations

Regional responses in antioxidant system to exercise training and dietary Vitamin E in aging rat brain

2003 • 152 citations

Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease.

1995 • 121 citations

Effects of Prolonged Exercise on Brain Ammonia and Amino Acids

1998 • 120 citations

Effect of physical exercise on mortality in patients with Parkinson's disease

1992 • 98 citations

Voluntary Running Provides Neuroprotection in Rats After 6-Hydroxydopamine Injection into the Medial Forebrain Bundle

2004 • 90 citations

Motor training effects on recovery of function after striatal lesions and striatal grafts

2003 • 81 citations

Causes of neuronal death in Parkinson's disease.

2001 • 66 citations

The Benefit of a Home Exercise Regimen for Ambulatory Parkinsonʼs Disease Patients

1989 • 61 citations

Induction of the Protective Antioxidant Response Element Pathway by 6-Hydroxydopamine In Vivo and In Vitro

2005 • 54 citations

Effect of acupuncture on 6-hydroxydopamine-induced nigrostratal dopaminergic neuronal cell death in rats

2005 • 52 citations

Changes in Motor Performance in Persons with Parkinsonʼs Disease After Exercise in a Mountain Area

1997 • 49 citations