Rab GTPases: specifying and deciphering organelle identity and function

Rab proteins as membrane organizers

2001 • 3,320 citations

The Biogenesis of Lysosomes

1989 • 1,583 citations

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1998 • 1,101 citations

Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11

2000 • 987 citations

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis.

1994 • 948 citations

A ras-like protein is required for a post-Golgi event in yeast secretion

1987 • 894 citations

The yeast GTP-binding YPT1 protein and a mammalian counterpart are associated with the secretion machinery

1988 • 699 citations

The Translocon: A Dynamic Gateway at the ER Membrane

1999 • 611 citations

A GTP-binding protein required for secretion rapidly associates with secretory vesicles and the plasma membrane in yeast

1988 • 592 citations

Rab9 functions in transport between late endosomes and the trans Golgi network.

1993 • 556 citations

Rab1 Recruitment of p115 into a cis-SNARE Complex: Programming Budding COPII Vesicles for Fusion

2000 • 459 citations

Transport-vesicle targeting: tethers before SNAREs

1999 • 451 citations

The mammalian Rab family of small GTPases: definition of family and subfamily sequence motifs suggests a mechanism for functional specificity in the Ras superfamily 1 1Edited by M. Yaniv

2000 • 446 citations

Hypervariable C-termmal domain of rab proteins acts as a targeting signal

1991 • 394 citations

TIP47: A Cargo Selection Device for Mannose 6-Phosphate Receptor Trafficking

1998 • 386 citations

Structural Basis of Rab Effector Specificity

1999 • 347 citations

GTPase activity of Rab5 acts as a timer for endocytic membrane fusion

1996 • 322 citations

Rab GTPases: master regulators of membrane trafficking

1994 • 315 citations

Membrane association of Rab5 mediated by GDP-dissociation inhibitor and accompanied by GDP/GTP exchange

1994 • 313 citations

Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network.

1994 • 306 citations

Ypt and Rab GTPases: insight into functions through novel interactions

2001 • 291 citations

GTP-binding proteins in intracellular transport

1992 • 277 citations

Matrix proteins can generate the higher order architecture of the Golgi apparatus

2000 • 262 citations

Role of Rab9 GTPase in Facilitating Receptor Recruitment by TIP47

2001 • 257 citations

Rab1 Interaction with a GM130 Effector Complex Regulates COPII Vesicle cis‐Golgi Tethering

2001 • 241 citations

Rab GDP Dissociation Inhibitor: Putting Rab GTPases in the Right Place

1995 • 240 citations

Membrane targeting of the small GTPase Rab9 is accompanied by nucleotide exchange

1994 • 230 citations

Identification of a GDI displacement factor that releases endosomal Rab GTPases from Rab-GDI

1997 • 218 citations

Trapp Stimulates Guanine Nucleotide Exchange on Ypt1p

2000 • 200 citations

Interactions of three domains distinguishing the Ras-related GTP-binding proteins Ypt1 and Sec4

1993 • 190 citations

Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p

2000 • 165 citations

A Novel Rab9 Effector Required for Endosome-to-TGN Transport

1997 • 138 citations

The Golgi matrix protein GM130: a specific interacting partner of the small GTPase rab1b

2001 • 116 citations

Crystal Structures of a Rab Protein in its Inactive and Active Conformations

2000 • 108 citations

Specificity domains distinguish the Ras-related GTPases Ypt1 and Sec4

1993 • 105 citations

Structural Plasticity of an Invariant Hydrophobic Triad in the Switch Regions of Rab GTPases Is a Determinant of Effector Recognition

2001 • 102 citations

Rab3A GTPase-activating protein-inhibiting activity of Rabphilin-3A, a putative Rab3A target protein.

1993 • 68 citations

Mitotic phosphorylation of rab4 prevents binding to a specific receptor on endosome membranes

1997 • 55 citations