2D or not 2D

Correlation between Protein and mRNA Abundance in Yeast

1999 • 3,800 citations

A generic protein purification method for protein complex characterization and proteome exploration

1999 • 2,699 citations

Two‐dimensional electrophoresis. The current state of two‐dimensional electrophoresis with immobilized pH gradients

1988 • 2,431 citations

The current state of two-dimensional electrophoresis with immobilized pH gradients

2000 • 1,498 citations

Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays

2000 • 1,356 citations

Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology

2000 • 1,323 citations

Membrane proteins and proteomics: Un amour impossible?

2000 • 850 citations

E-CELL: software environment for whole-cell simulation.

1999 • 781 citations

A Sampling of the Yeast Proteome

1999 • 629 citations

The dynamic range of protein expression: A challenge for proteomic research

2000 • 599 citations

Extraction of membrane proteins by differential solubilization for separation using two‐dimensional gel electrophoresis

1998 • 499 citations

A thousand points of light: The application of fluorescence detection technologies to two-dimensional gel electrophoresis and proteomics

2000 • 326 citations

Antibodies in diagnostics – from immunoassays to protein chips

2000 • 318 citations

The Yeast Proteome Database (YPD) and Caenorhabditis elegans Proteome Database (WormPD): comprehensive resources for the organization and comparison of model organism protein information

2000 • 290 citations

High-throughput mass spectrometric discovery of protein post-translational modifications

1999 • 289 citations

Towards higher resolution: Two-dimensional Electrophoresis ofSaccharomyces cerevisiae proteins using overlapping narrow immobilized pH gradients

2000 • 276 citations

Phosphate Starvation-Inducible Proteins of Bacillus subtilis : Proteomics and Transcriptional Analysis

2000 • 247 citations

Large-scale functional analysis using peptide or protein arrays

2000 • 241 citations

Comparative proteome analysis of Helicobacter pylori

2000 • 241 citations

A post-genomic challenge: learning to read patterns of protein synthesis

1999 • 231 citations

Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae

1998 • 217 citations

Proteome analysis of rat hepatic stellate cells

2000 • 203 citations

Proteomics: Capacityversus utility

2000 • 163 citations

A Method for Global Analysis of Complex Proteomes Using Sample Prefractionation by Solution Isoelectrofocusing Prior to Two-Dimensional Electrophoresis

2000 • 162 citations

Towards high performance two-dimensional gel electrophoresis using ultrazoom gels

2000 • 160 citations

Role of CcpA in Regulation of the Central Pathways of Carbon Catabolism in Bacillus subtilis

1999 • 157 citations

Biomedical applications of two-dimensional electrophoresis using immobilized pH gradients: Current status

2000 • 154 citations

Phospho-proteomics: Evaluation of the use of enzymatic de-phosphorylation and differential mass spectrometric peptide mass mapping for site specific phosphorylation assignment in proteins separated by gel electrophoresis

2001 • 152 citations

Interlaboratory reproducibility of yeast protein patterns analyzed by immobilized pH gradient two‐dimensional gel electrophoresis

1995 • 152 citations

Genome‐wide protein interaction maps using two‐hybrid systems

2000 • 149 citations

Analysis of membrane proteins by two-dimensional electrophoresis: Comparison of the proteins extracted from normal orPlasmodium falciparum - infected erythrocyte ghosts

1999 • 144 citations

Proteome studies of Saccharomyces cerevisiae: Identification and characterization of abundant proteins

1997 • 140 citations

Multiple stress responses in Streptococcus mutans and the induction of general and stress-specific proteins

2000 • 134 citations

Subproteomics based upon protein cellular location and relative solubilities in conjunction with composite two-dimensional electrophoresis gels

2000 • 133 citations

Mass spectrometic detection for capillary isoelectric focusing separations of complex protein mixtures

2000 • 124 citations

A Molecular Scanner To Automate Proteomic Research and To Display Proteome Images

1999 • 124 citations

By-passing selection: direct screening for antibody-antigen interactions using protein arrays

2000 • 122 citations

Anchored multiplex amplification on a microelectronic chip array

2000 • 109 citations

Bladder squamous cell carcinoma biomarkers derived from proteomics

2000 • 107 citations

Proteome analysis reveals ubiquitin‐conjugating enzymes to be a new family of interferon‐α‐regulated genes

2000 • 98 citations

High-Efficiency Capillary Isoelectric Focusing of Peptides

2000 • 92 citations

The proteome of Mycoplasma genitalium

2000 • 90 citations

Detection and Quantification of Neurotensin in Human Brain Tissue by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

2000 • 86 citations

Comparative proteome analysis of the hippocampus implicates chromosome 6q in schizophrenia

2000 • 82 citations

New algorithmic approaches to protein spot detection and pattern matching in two-dimensional electrophoresis gel databases

1999 • 81 citations

Comprehensive analyses of prostate gene expression: Convergence of expressed sequence tag databases, transcript profiling and proteomics

2000 • 79 citations

Proteome analysis of Saccharomyces cerevisiae: A methodological outline

1997 • 75 citations

Proteome Analysis of Interleukin-1β–Induced Changes in Protein Expression in Rat Islets of Langerhans

2001 • 71 citations

Improved sensitivity proteomics by postharvest alkylation and radioactive labeling of proteins

2000 • 63 citations

Two-dimensional gel analysis of the proteome of lager brewing yeasts

2000 • 63 citations

Laser-assisted microdissection: applications in molecular pathology

1999 • 60 citations

MALDI-TOF mass spectrometry in protein chemistry

2000 • 48 citations

Point pattern matching in the analysis of two-dimensional gel electropherograms

1999 • 48 citations

Proteomic analysis of differential protein expression in primary hepatocytes induced by EGF, tumour necrosis factor α or the peroxisome proliferator nafenopin

2000 • 47 citations

Two-Dimensional Gel Electrophoresis of Rat Islet Proteins: Interleukin 1β-Induced Changes in Protein Expression are Reduced by <scp>L</scp>-Arginine Depletion and Nicotinamide

1995 • 45 citations

Mass spectrometric characterization of stathmin isoforms separated by 2D PAGE

1999 • 42 citations

Biosequence Exegesis

1999 • 40 citations

Enrichment of hydrophobic proteinsvia Triton X-114 phase partitioning and hydroxyapatite column chromatography for mass spectrometry

2000 • 40 citations

Can Celera Do It Again?

2000 • 39 citations

Proteome analysis ofOncorhynchus species during embryogenesis

2000 • 30 citations

Luteinizing Hormone Induces Mouse Vas Deferens Protein Expression in the Murine Ovary

2000 • 27 citations

Urological malignancies and the proteomic-genomic interface

1999 • 21 citations

Flicker Image Comparison of 2-D Gel Images for Putative Protein Identification using the 2DWG Meta-Database

1999 • 20 citations

Single allele knock-out of Candida albicans CGT1 leads to unexpected resistance to hygromycin B and elevated temperature

2000 • 19 citations

Automation of yeast two-hybrid screening.

1999 • 19 citations

Mining protein data from two-dimensional gels: Tools for systematic post-planned analyses

1999 • 14 citations

Two-dimensional gel electrophoresis of rat islet proteins. Interleukin 1 beta-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide

1995 • 11 citations

Luteinizing Hormone Induces Mouse Vas Deferens Protein Expression in the Murine Ovary

2000 • 8 citations

Identification of isoprenyl modified proteins metabolically labeled with [³H]farnesyl‐ and [³H]geranylgeranyl‐pyrophosphate

1996 • 4 citations

Deleted Work

1955 • 0 citations