Critical role of helix 12 of the vitamin D 3 receptor for the partial agonism of carboxylic ester antagonists 1 1Edited by R. Huber

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Molecular basis of agonism and antagonism in the oestrogen receptor

1997 • 3,285 citations

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

The Structural Basis of Estrogen Receptor/Coactivator Recognition and the Antagonism of This Interaction by Tamoxifen

1998 • 2,622 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors.

1996 • 1,095 citations

The nuclear receptor ligand-binding domain: structure and function

1998 • 829 citations

The Crystal Structure of the Nuclear Receptor for Vitamin D Bound to Its Natural Ligand

2000 • 802 citations

Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*

1994 • 789 citations

Orphan Nuclear Receptors: From Gene to Function*

1999 • 789 citations

The nuclear receptor superfamily

2003 • 583 citations

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

1998 • 580 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

2000 • 459 citations

Steroid Hormone Receptors

1976 • 345 citations

The Molecular Pharmacology of SERMs

1999 • 307 citations

Mechanisms of Nuclear Signalling by Vitamin D3. Interplay with Retinoid and Thyroid Hormone Signalling

1995 • 186 citations

Gene Regulation by Vitamin D3

1998 • 185 citations

Antagonistic Action of Novel 1α,25-Dihydroxyvitamin D3-26,23-lactone Analogs on Differentiation of Human Leukemia Cells (HL-60) Induced by 1α,25-Dihydroxyvitamin D3

1999 • 108 citations

All natural DR3-type vitamin D response elements show a similar functionality in vitro

2000 • 97 citations

Different Molecular Mechanisms of Vitamin D₃ Receptor Antagonists

2001 • 74 citations

The vitamin D3 receptor in the context of the nuclear receptor superfamily

1996 • 72 citations

Antagonistic Action of a 25-Carboxylic Ester Analogue of 1α,25-Dihydroxyvitamin D3 Is Mediated by a Lack of Ligand-induced Vitamin D Receptor Interaction with Coactivators

2000 • 69 citations

Analysis of the Molecular Mechanism for the Antagonistic Action of a Novel 1α,25-Dihydroxyvitamin D3 Analogue toward Vitamin D Receptor Function

1999 • 68 citations

Ligand-triggered stabilization of vitamin D Receptor/Retinoid X receptor heterodimer conformations on DR4-type response elements

2000 • 65 citations

Orphan Nuclear Receptors

2000 • 62 citations

Structure Activity Relationship of Carboxylic Ester Antagonists of the Vitamin D₃ Receptor

2000 • 59 citations

Carboxylic ester antagonists of 1α,25-dihydroxyvitamin D3 show cell-specific actions

2000 • 57 citations

25-Dehydro-1α-Hydroxyvitamin D3- 26,23S-Lactone Antagonizes the Nuclear Vitamin D Receptor by Mediating a Unique Noncovalent Conformational Change

2000 • 43 citations

The High Affinity Ligand Binding Conformation of the Nuclear 1,25-dihydroxyvitamin D3 Receptor is Functionally Linked to the Transactivation Domain 2 (AF-2)

1996 • 38 citations

Regulation of Ligand-Induced Heterodimerization and Coactivator Interaction by the Activation Function-2 Domain of the Vitamin D Receptor

2000 • 37 citations

Computer determination of peptide conformations in water: different roads to structure.

1995 • 32 citations

Recent developments in molecular action of antihormones

1998 • 26 citations