Fas/CD95/APO‐1 Can Function as a Death Receptor for Neuronal Cells in Vitro and in Vivo and is Upregulated Following Cerebral Hypoxic‐Ischemic Injury to the Developing Rat Brain

Apoptosis in the Pathogenesis and Treatment of Disease

1995 • 6,610 citations

Apoptosis by Death Factor

1997 • 5,038 citations

The Fas Death Factor

1995 • 4,070 citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

1996 • 3,065 citations

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

1995 • 2,436 citations

Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor.

1995 • 2,142 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)

1997 • 1,207 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1996 • 947 citations

FADD: Essential for Embryo Development and Signaling from Some, But Not All, Inducers of Apoptosis

1998 • 893 citations

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

1998 • 704 citations

Downregulation of Fas ligand by shedding

1998 • 681 citations

A Stereotaxic Atlas of the Developing Rat Brain

1970 • 589 citations

In situ end‐labelling detects DNA strand breaks in apoptosis and other physiological and pathological states

1993 • 584 citations

Antigen Retrieval Immunohistochemistry: Past, Present, and Future

1997 • 516 citations

Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain

1993 • 481 citations

Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover.

1996 • 464 citations

CD95 Ligand (Fas-L/APO-1L) and Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Mediate Ischemia-Induced Apoptosis in Neurons

1999 • 435 citations

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

1997 • 403 citations

Multiple Sclerosis: Fas Signaling in Oligodendrocyte Cell Death

1996 • 362 citations

Lasting N-Terminal Phosphorylation of c-Jun and Activation of c-Jun N-Terminal Kinases after Neuronal Injury

1998 • 330 citations

Unraveling Immune Privilege

1995 • 302 citations

Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain.

1996 • 283 citations

Cerebral Hypoxia-Ischemia Stimulates Cytokine Gene Expression in Perinatal Rats

1995 • 282 citations

Ultrastructural and light microscopic evidence of apoptosis after middle cerebral artery occlusion in the rat.

1995 • 258 citations

Oxford Textbook of Pathology

1994 • 210 citations

CYTOKINES AND PERINATAL BRAIN INJURY

1997 • 167 citations

Fas/Apo [apoptosis]-1 and associated proteins in the differentiating cerebral cortex: induction of caspase-dependent cell death and activation of NF-kappaB.

1999 • 157 citations

Evidence of Nuclear DNA Fragmentation Following Hypoxia‐Ischemia in the Infant Rat Brain, and Transient Forebrain Ischemia in the Adult Gerbil

1994 • 150 citations

Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat

1996 • 147 citations

Fas antigen signals proliferation of normal human diploid fibroblast and its mechanism is different from tumor necrosis factor receptor

1995 • 132 citations

Fas antigen expression in brains of patients with Alzheimer-type dementia

1995 • 132 citations

Increased apoptosis in the cingulate sulcus of newborn piglets following transient hypoxia-ischaemia is related to the degree of high energy phosphate depletion during the insult

1994 • 130 citations

Apoptosis in the Brains of Infants Suffering Intrauterine Cerebral Injury

1997 • 128 citations

Fas/Apo [Apoptosis]-1 and Associated Proteins in the Differentiating Cerebral Cortex: Induction of Caspase-Dependent Cell Death and Activation of NF-κB

1999 • 120 citations

Myelin oligodendrocyte glycoprotein‐induced autoimmune encephalomyelitis is chronic/relapsing in perforin knockout mice, but monophasic in Fas‐ and Fas ligand‐deficient lpr and gld mice

1997 • 101 citations

Apoptosis in neural development and disease

1997 • 90 citations

Activation-induced Aggregation and Processing of the Human Fas Antigen

1997 • 82 citations

Expression of Fas Antigen in the Normal Mouse Brain

1998 • 81 citations

Fas expression on human fetal astrocytes without susceptibility to fas-mediated cytotoxicity

1998 • 79 citations

Fas antigen mRNA induction in postischemic murine brain

1994 • 76 citations

Localization of Fas antigen mRNA induced in postischemic murine forebrain by in situ hybridization

1995 • 75 citations

Poly(ADP ribose) polymerase cleavage precedes neuronal death in the hippocampus and cerebellum following injury to the developing rat forebrain

1999 • 67 citations

CD95–CD95L: can the brain learn from the immune system?

1998 • 65 citations

Expression of Fas Ligand and Its Receptor in Cutaneous Lupus: Implication in Tissue Injury

1997 • 62 citations

Delayed selective motor neuron death and Fas antigen induction after spinal cord ischemia in rabbits

1998 • 56 citations

Annexin V labels apoptotic neurons following hypoxia-ischemia

1997 • 55 citations

Evidence for neuronal apoptosis in pontosubicular neuron necrosis

1996 • 52 citations

EDITORIAL. REGULATION OF APOPTOSIS BY Bcl-2 AND ITS RELATED PROTEINS: IMMUNOCHEMICAL CHALLENGES AND THERAPEUTIC IMPLICATIONS

1996 • 44 citations

In situ expression of protooncogenes and Fas/Fas ligand in rheumatoid arthritis synovium.

1997 • 41 citations

High temperature antigen retrieval and loss of nuclear morphology: a comparison of microwave and autoclave techniques.

1996 • 14 citations