The Saccharomyces cerevisiae Sko1p transcription factor mediates HOG pathway‐dependent osmotic regulation of a set of genes encoding enzymes implicated in protection from oxidative damage
Data up to Jan 2025
Total Citations Per Year
Abstract
References (77)
Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes
2000 • 4,803 citations
Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale
1997 • 4,531 citations
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites
1988 • 2,903 citations
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 • 2,692 citations
Elevated recombination rates in transcriptionally active DNA
1989 • 1,666 citations
An Osmosensing Signal Transduction Pathway in Yeast
1993 • 1,252 citations
The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).
1996 • 1,050 citations
MAP Kinase Pathways in the Yeast Saccharomyces cerevisiae
1998 • 939 citations
Replacement of chromosome segments with altered DNA sequences constructed in vitro.
1979 • 779 citations
Crystal structure of the heterodimeric bZIP transcription factor c-Fos–c-Jun bound to DNA
1995 • 718 citations
Yeast Stress Responses
2002 • 592 citations
The H2O2 Stimulon in Saccharomyces cerevisiae
1998 • 564 citations
Yap1 and Skn7 Control Two Specialized Oxidative Stress Response Regulons in Yeast
1999 • 548 citations
The Transcriptional Response of Saccharomyces cerevisiae to Osmotic Shock
2000 • 546 citations
The HOG pathway controls osmotic regulation of transcription via the stress response element (STRE) of the Saccharomyces cerevisiae CTT1 gene.
1994 • 511 citations
H2O2 sensing through oxidation of the Yap1 transcription factor
2000 • 507 citations
A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions.
1993 • 470 citations
Regulation of yAP-1 nuclear localization in response to oxidative stress
1997 • 437 citations
Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.
1996 • 419 citations
Stress signaling in yeast
1995 • 415 citations
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1
1998 • 414 citations
The Atf1 transcription factor is a target for the Sty1 stress-activated MAP kinase pathway in fission yeast.
1996 • 365 citations
A novel P‐type ATPase from yeast involved in sodium transport
1991 • 362 citations
The YDp plasmids: A uniform set of vectors bearing versatile gene disruption cassettes for Saccharomyces cerevisiae
1991 • 342 citations
Turning genes off by Ssn6–Tup1: a conserved system of transcriptional repression in eukaryotes
2000 • 328 citations
Snf1 Protein Kinase Regulates Phosphorylation of the Mig1 Repressor in Saccharomyces cerevisiae
1998 • 320 citations
Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1
1998 • 304 citations
Activation and Regulation of the Spc1 Stress-Activated Protein Kinase in Schizosaccharomyces pombe
1996 • 300 citations
The Skn7 response regulator controls gene expression in the oxidative stress response of the budding yeast Saccharomyces cerevisiae
1997 • 284 citations
Osmotic Stress-Induced Gene Expression in Saccharomyces cerevisiae Requires Msn1p and the Novel Nuclear Factor Hot1p
1999 • 275 citations
Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway
2000 • 253 citations
Regulation of the Sko1 transcriptional repressor by the Hog1 MAP kinase in response to osmotic stress
2001 • 214 citations
Kinase Activity-dependent Nuclear Export Opposes Stress-induced Nuclear Accumulation and Retention of Hog1 Mitogen-activated Protein Kinase in the Budding YeastSaccharomyces cerevisiae
1999 • 212 citations
A search in the genome ofSaccharomyces cerevisiae for genes regulated via stress response elements
1998 • 204 citations
A novel and conserved salt-induced protein is an important determinant of salt tolerance in yeast.
1992 • 203 citations
The role of the YAP1 and YAP2 genes in the regulation of the adaptive oxidative stress responses of Saccharomyces cerevisiae
1995 • 200 citations
The PMR2 gene cluster encodes functionally distinct isoforms of a putative Na+ pump in the yeast plasma membrane.
1995 • 189 citations
A glutathione reductase mutant of yeast accumulates high levels of oxidized glutathione and requires thioredoxin for growth.
1996 • 188 citations
Metabolic and Regulatory Changes Associated with Growth of Saccharomyces cerevisiae in 1.4 M NaCl
1997 • 186 citations
The yeast histidine protein kinase, Sln1p, mediates phosphotransfer to two response regulators, Ssk1p and Skn7p
1998 • 183 citations
Repressors and Upstream Repressing Sequences of the Stress-Regulated ENA1 Gene in Saccharomyces cerevisiae: bZIP Protein Sko1p Confers HOG-Dependent Osmotic Regulation
1999 • 181 citations
A New Antioxidant with Alkyl Hydroperoxide Defense Properties in Yeast
1999 • 178 citations
Signal transduction by MAP kinase cascades in budding yeast
1998 • 170 citations
Multistep Phosphorelay Proteins Transmit Oxidative Stress Signals to the Fission Yeast Stress-activated Protein Kinase
2000 • 165 citations
The Skn7 Response Regulator ofSaccharomyces cerevisiaeInteracts with Hsf1 In Vivo and Is Required for the Induction of Heat Shock Genes by Oxidative Stress
2000 • 164 citations
Stress‐activated signalling pathways in yeast
1998 • 159 citations
Arabidopsis thaliana NADPH Oxidoreductase Homologs Confer Tolerance of Yeasts toward the Thiol-oxidizing Drug Diamide
1995 • 159 citations
The response regulator-like protein Pos9/Skn7 ofSaccharomyces cerevisiae is involved in oxidative stress resistance
1996 • 151 citations
Polarized localization of yeast Pbs2 depends on osmostress, the membrane protein Sho1 and Cdc42
2000 • 147 citations
Three genes whose expression is induced by stress inSaccharomyces cerevisiae
1999 • 146 citations
Yeast putative transcription factors involved in salt tolerance
1998 • 136 citations
Negative control of the Mig1p repressor by Snf1p‐dependent phosphorylation in the absence of glucose
1998 • 135 citations
Multiple transduction pathways regulate the sodium‐extrusion gene PMR2/ENA1 during salt stress in yeast
1996 • 134 citations
Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response.
1994 • 132 citations
Multiple modes of activation of the stress-responsive MAP kinase pathway in fission yeast
1997 • 131 citations
Differential Requirement of the Yeast Sugar Kinases for Sugar Sensing in Establishing the Catabolite‐Repressed State
1996 • 126 citations
Different signalling pathways contribute to the control of GPD1 gene expression by osmotic stress in Saccharomyces cerevisiae
1999 • 126 citations
YeastSKO1gene encodes a bZIP protein that binds to the CRE motif and acts as a repressor of transcription
1992 • 113 citations
Glucose repression affects ion homeostasis in yeast through the regulation of the stress‐activated ENA1 gene
1997 • 111 citations
A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme
2000 • 105 citations
Stimulation of the yeast high osmolarity glycerol (HOG) pathway: evidence for a signal generated by a change in turgor rather than by water stress
2000 • 98 citations
Molecular structure and genetic regulation of SFA, a gene responsible for resistance to formaldehyde in Saccharomyces cerevisiae, and characterization of its protein product
1993 • 96 citations
Chromatin-mediated transcription repression in yeast
1995 • 94 citations
Yeast Skn7p activity is modulated by the Sln1p-Ypd1p osmosensor and contributes to regulation of the HOG pathway
1998 • 83 citations
ACR1, a yeast ATF/CREB repressor.
1992 • 82 citations
Mechanisms of Salt Tolerance Conferred by Overexpression of the HAL1 Gene in Saccharomyces cerevisiae
1997 • 81 citations
Aca1 and Aca2, ATF/CREB Activators in Saccharomyces cerevisiae, Are Important for Carbon Source Utilization but Not the Response to Stress
2000 • 71 citations
The Ssn6-Tup1 repressor complex of Saccharomyces cerevisiae is involved in the osmotic induction of HOG-dependent and -independent genes
1998 • 69 citations
Mechanisms of Salt Tolerance Conferred by Overexpression of theHAL1 Gene inSaccharomyces cerevisiae
1997 • 65 citations
The effect of tea tree oil and antifungal agents on a reporter for yeast cell integrity signalling
2007 • 63 citations
The Sko1p Repressor and Gcn4p Activator Antagonistically Modulate Stress-Regulated Transcription in Saccharomyces cerevisiae
2001 • 55 citations
Role of Atfl and Papl in the Induction of the Catalase Gene of Fission Yeast Schizosaccharomyces pombe
2000 • 46 citations
Strategy for deletion of complete open reading frames in Saccharomyces cerevisiae
1995 • 34 citations
Rap1p-binding Sites in the Saccharomyces cerevisiae GPD1 Promoter Are Involved in Its Response to NaCl
2000 • 24 citations
YAP1 Encodes a Yeast Homolog of Mammalian Transcription Factor AP-1
1988 • 17 citations
A Double Residue Substitution in the Coenzyme-binding Site Accounts for the Different Kinetic Properties between Yeast and Human Formaldehyde Dehydrogenases
1999 • 16 citations
The response regulator-like protein Pos9/Skn7 of Saccharomyces cerevisiae is involved in oxidative stress resistance
1996 • 14 citations