Differences in patterns ofTP53 andKRAS2 mutations in a large series of endometrial carcinomas with or without microsatellite instability

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

1993 • 2,884 citations

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

A rapid non-enzymatic method for the preparation of HMW DNA from blood for RFLP studies

1991 • 2,314 citations

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

1993 • 2,282 citations

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

1994 • 2,071 citations

Mutation of a mutL Homolog in Hereditary Colon Cancer

1994 • 1,834 citations

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

1994 • 1,544 citations

Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype

1997 • 1,329 citations

Mutations in the RET proto-oncogene are associated with MEN 2A and FMTC

1993 • 1,273 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer.

1995 • 743 citations

Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies.

1997 • 689 citations

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients.

1994 • 622 citations

MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.

1997 • 464 citations

Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer

1996 • 451 citations

Announcements

1989 • 378 citations

Microsatellite instability in endometrial carcinoma.

1994 • 228 citations

Overexpression and mutation of p53 in endometrial carcinoma.

1992 • 227 citations

Clinical and pathological significance of microsatellite instability in sporadic endometrial carcinoma.

1996 • 185 citations

Allelic loss of sequences from the long arm of chromosome 10 and replication errors in endometrial cancers.

1995 • 181 citations

Mutation of the Ki-ras protooncogene in human endometrial hyperplasia and carcinoma.

1993 • 176 citations

Microsatellite instability analysis: a multicenter study for reliability and quality control.

1997 • 166 citations

Alterations of the p53 tumor suppressor gene and its association with activation of the c-K-ras-2 protooncogene in premalignant and malignant lesions of the human uterine endometrium.

1993 • 131 citations

Prognostic significance of p53 overexpression in endometrial cancer.

1994 • 106 citations

Mutational analysis ofMLH1 andMSH2 in 25 prospectively-acquired RER+ endometrial cancers

1997 • 106 citations

Microsatellite instability in endometrial carcinomas: Frequent replication errors in tumors of early onset and/or of poorly differentiated type

1995 • 103 citations

Genomic structure of the transforming growth factor beta type II receptor gene and its mutations in hereditary nonpolyposis colorectal cancers.

1996 • 96 citations

Uteri of women with endometrial carcinoma contain a histopathological spectrum of monoclonal putative precancers, some with microsatellite instability.

1996 • 91 citations

Early mutational activation of the c-Ki-ras oncogene in endometrial carcinoma.

1994 • 90 citations

GENOMIC INSTABILITY IN COLORECTAL CARCINOMAS: COMPARISON OF DIFFERENT EVALUATION METHODS AND THEIR BIOLOGICAL SIGNIFICANCE

1996 • 70 citations

Mutations of the Ki-ras oncogene in endometrial carcinoma

1992 • 68 citations

K-rasPoint Mutations in Endometrial Carcinoma: Effect on Outcome Is Dependent on Age of Patient

1996 • 55 citations

Mutations inMLH1 are more frequent than inMSH2 in sporadic colorectal cancers with microsatellite instability

1997 • 54 citations

Allelic loss of chromosome 17p, mutation of the p53 gene, and microsatellite instability in right- and left-sided colorectal cancer

1996 • 49 citations

Studies on Ras Oncogene Activation in Endometrial Carcinoma

1993 • 48 citations

Absence ofTP53 alterations in pheochromocytomas and medullary thyroid carcinomas

1997 • 44 citations

Alteration of the p53 Tumor Suppressor Gene and Activation of c-K-ras-2 Protooncogene in Endometrial Adenocarcinoma From Colorado

1995 • 42 citations

CLINICO-PATHOLOGICAL FEATURES AND p53 EXPRESSION IN LEFT-SIDED SPORADIC COLORECTAL CANCERS WITH AND WITHOUT MICROSATELLITE INSTABILITY

1996 • 28 citations

Mutation Analysis of K-rasOncogenes in Gastroenterologic Cancers by the Amplified Created Restriction Sites Method

1993 • 27 citations