GENOMIC INSTABILITY IN COLORECTAL CARCINOMAS: COMPARISON OF DIFFERENT EVALUATION METHODS AND THEIR BIOLOGICAL SIGNIFICANCE

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

1993 • 2,711 citations

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1995 • 824 citations

Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.

1994 • 807 citations

Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history.

1993 • 796 citations

A NEW PROGNOSTIC CLASSIFICATION OF RECTAL CANCER

1987 • 695 citations

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms

1994 • 513 citations

Crohn's-like lymphoid reaction and colorectal carcinoma: a potential histologic prognosticator.

1990 • 282 citations

Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction.

1992 • 253 citations

Optimized oligonucleotide probes for DNA fingerprinting

1988 • 146 citations

Detection of somatic changes in human cancer DNA by DNA fingerprint analysis

1987 • 133 citations

The relationship of DNA aneuploidy to molecular genetic alterations in colorectal carcinoma

1992 • 120 citations

Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry

1990 • 89 citations

Detection of microsatellite instability in human colorectal carcinomas using a non-radioactive PCR-based screening technique

1995 • 51 citations

Microsatellite instability: new aspects in the carcinogenesis of colorectal carcinoma

1995 • 49 citations

Hereditary nonpoiyposis colorectal cancer (lynch syndrome II): Diploid malignancies with prolonged survival

1992 • 42 citations

The relationship between aneuploidy and p53 overexpression during genesis of colorectal adenocarcinoma

1994 • 40 citations

In vitro and ex vivo expression of nucleolar proteins B23 and p120 in benign and malignant epithelial lesions of the prostate.

1995 • 25 citations

Biologic Characterization of Hereditary Non-Polyposis Colorectal Cancer:Nuclear Ploidy, AgNOR Count, Microvessel Distribution, Oncogene Expression, and Grade-Related Parameters

1995 • 24 citations