Purification of intracellular compartments involved in antigen processing: a new method based on magnetic sorting

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

1990 • 1,150 citations

The diversity of Rab proteins in vesicle transport

1997 • 762 citations

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments

1991 • 663 citations

[27] Rapid colorimetric micromethod for the quantitation of complexed iron in biological samples

1988 • 592 citations

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1994 • 442 citations

Isolation and characterization of the intracellular MHC class II compartment

1994 • 426 citations

The coated pit and macropinocytic pathways serve distinct endosome populations

1994 • 374 citations

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1994 • 349 citations

Enhanced Dissociation of HLA-DR-Bound Peptides in the Presence of HLA-DM

1996 • 327 citations

Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

1991 • 326 citations

Molecular characterization of phagosomes.

1994 • 287 citations

Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments

1997 • 233 citations

HLA-DM Interactions with Intermediates in HLA-DR Maturation and a Role for HLA-DM in Stabilizing Empty HLA-DR Molecules

1996 • 206 citations

Processed antigen binds to newly synthesized mhc class II molecules in antigen-specific B lymphocytes

1991 • 188 citations

Differential expression and serologically distinct subpopulations of human Ia antigens detected with monoclonal antibodies to Ia alpha and beta chains

1982 • 183 citations

Endosomal aspartic proteinases are required for invariant-chain processing.

1994 • 182 citations

Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation

1996 • 170 citations

Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture.

1991 • 158 citations

The small gtp-binding protein rab6p is distributed from medial golgi to the Trans-golgi network as determined by a confocal microscopic approach

1992 • 138 citations

A silver stain protocol for proteins yielding high resolution and transparent background in sodium dodecyl sulfate‐polyacrylamide gels

1995 • 133 citations

Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment.

1993 • 124 citations

MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.

1995 • 122 citations

Role of B cell receptor Igα and Igβ subunits in MHC class II-restricted antigen presentation

1995 • 115 citations

Characterization of lysosomes isolated from Dictyostelium discoideum by magnetic fractionation.

1993 • 94 citations

Role of cathepsin D in antigen presentation of ovalbumin.

1992 • 93 citations

Intracellular targeting of antigens internalized by membrane immunoglobulin in B lymphocytes.

1995 • 91 citations

Type II and III Receptors for Immunoglobulin G (IgG) Control the Presentation of Different T Cell Epitopes from Single IgG-complexed Antigens

1998 • 88 citations

Peptide loading onto recycling HLA-DR molecules occurs in early endosomes

1998 • 75 citations

Identification of major proteins associated with Dictyostelium discoideum endocytic vesicles

1995 • 59 citations

Covalent binding of C3b to tetanus toxin: influence on uptake/internalization of antigen by antigen‐specific and non‐specific B cells

1996 • 49 citations

Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexes

1997 • 45 citations

Intracellular signaling and endosomal trafficking of immunoreceptors

1997 • 17 citations

Inhibition by brefeldin A of the specific B cell antigen presentation to MHC class II-restricted T cells.

1991 • 16 citations

Requirement for Protein Synthesis in Antigen Processing by B Cells

1994 • 7 citations

Differential Sensitivity to Antigenic Competition in Antigen-Specific and -Nonspecific Antigen Presentation by B Cells

1995 • 3 citations