Intracellular targeting of antigens internalized by membrane immunoglobulin in B lymphocytes.

Antigen-specific interaction between T and B cells

1985 • 1,396 citations

ANALYTICAL STUDY OF MICROSOMES AND ISOLATED SUBCELLULAR MEMBRANES FROM RAT LIVER

1974 • 840 citations

Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis

1990 • 508 citations

Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes

1994 • 442 citations

Antigen presentation by hapten-specific B lymphocytes. I. Role of surface immunoglobulin receptors.

1984 • 422 citations

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

1990 • 377 citations

The low density lipoprotein receptor. Identification of amino acids in cytoplasmic domain required for rapid endocytosis.

1987 • 355 citations

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

1994 • 349 citations

Interaction between a "processed" ovalbumin peptide and Ia molecules.

1986 • 247 citations

Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta.

1993 • 237 citations

Separation of subcellular compartments containing distinct functional forms of MHC class II.

1994 • 221 citations

Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4- and interleukin 2-producing T cell clones on resting B lymphocytes.

1988 • 198 citations

Localization of the signal for rapid internalization of the bovine cation-independent mannose 6-phosphate/insulin-like growth factor-II receptor to amino acids 24-29 of the cytoplasmic tail.

1991 • 188 citations

Mutations of immunoglobulin transmembrane and cytoplasmic domains: Effects on intracellular signaling and antigen presentation

1990 • 154 citations

Role of membrane immunoglobulin (Ig) crosslinking in membrane Ig-mediated, major histocompatibility-restricted T cell-B cell cooperation.

1985 • 131 citations

Antigen presentation by the B cell antigen receptor is driven by the αβ sheath and occurs independently of its cytoplasmic tyrosines

1993 • 101 citations

Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structures.

1988 • 100 citations

Endocytosis and recycling of specific antigen by human B cell lines.

1988 • 89 citations

Endocytosis, intracellular trafficking, and processing of membrane IgG and monovalent antigen/membrane IgG complexes in B lymphocytes.

1990 • 85 citations

The amino terminus of GLUT4 functions as an internalization motif but not an intracellular retention signal when substituted for the transferrin receptor cytoplasmic domain

1994 • 80 citations

Signaling-defective mutants of the B lymphocyte antigen receptor fail to associate with Ig-alpha and Ig-beta/gamma.

1993 • 76 citations

Glycosyl-phosphatidylinositol linkage as a mechanism for cell-surface expression of immunoglobulin D

1992 • 68 citations

Cytoplasmic tail deletion converts membrane immunoglobulin to a phosphatidylinositol-linked form lacking signaling and efficient antigen internalization functions

1991 • 57 citations

A mutation of the mu transmembrane that disrupts endoplasmic reticulum retention. Effects on association with accessory proteins and signal transduction.

1994 • 54 citations

Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules.

1988 • 51 citations

Detection of functional class II-associated antigen: role of a low density endosomal compartment in antigen processing.

1995 • 47 citations

Antigen entry into early endosomes is insufficient for MHC class II processing.

1993 • 36 citations

Secretion by mononuclear phagocytes of lysosomal hydrolases bearing ligands for the mannose-6-phosphate receptor system of fibroblasts: Evidence for a second mechanism of spontaneous secretion?

1982 • 36 citations

Exogenous antigens internalized through transferrin receptors activate CD4+ T cells.

1993 • 36 citations

Differential structure-function requirements of the transmembranal domain of the B cell antigen receptor.

1992 • 35 citations

Point mutations define a mIgM transmembrane region motif that determines intersubunit signal transduction in the antigen receptor.

1994 • 33 citations

Role of the B cell antigen receptor in antigen processing and presentation. Involvement of the transmembrane region in intracellular trafficking of receptor/ligand complexes.

1993 • 16 citations