Signaling pathways and late-onset gene induction associated with renal mesangial cell hypertrophy

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

2001 • 9,275 citations

Rho GTPases and the Actin Cytoskeleton

1998 • 6,129 citations

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1995 • 5,143 citations

Specificity and mechanism of action of some commonly used protein kinase inhibitors

2000 • 4,109 citations

Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation

2001 • 3,295 citations

RNA interference is mediated by 21- and 22-nucleotide RNAs

2001 • 3,271 citations

Mechanism of activation of protein kinase B by insulin and IGF-1.

1996 • 2,965 citations

The Continuing Epidemics of Obesity and Diabetes in the United States

2001 • 2,803 citations

Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Bα

1997 • 2,747 citations

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy

1998 • 2,570 citations

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

2001 • 2,488 citations

Transcriptional regulation by the phosphorylation-dependent factor CREB

2001 • 2,488 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Ten years of protein kinase B signalling: a hard Akt to follow

2001 • 1,159 citations

Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer

2001 • 1,153 citations

Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity

1991 • 1,071 citations

PKB/Akt

2001 • 1,066 citations

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activationofCREB

1998 • 975 citations

Cardiac Muscle Cell Hypertrophy and Apoptosis Induced by Distinct Members of the p38 Mitogen-activated Protein Kinase Family

1998 • 855 citations

The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice

2000 • 778 citations

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1997 • 740 citations

PKB/AKT: functional insights from genetic models

2001 • 611 citations

Regulation of gene expression by insulin

1996 • 543 citations

An Evolutionarily Conserved Family of Hsp70/Hsc70 Molecular Chaperone Regulators

1999 • 509 citations

Getting your Pax straight: Pax proteins in development and disease

2002 • 476 citations

Activated glycogen synthase-3β suppresses cardiac hypertrophy in vivo

2002 • 467 citations

Glycogen Synthase Kinase-3β Is a Negative Regulator of Cardiomyocyte Hypertrophy

2000 • 390 citations

Membrane traffic in polarized epithelial cells

2000 • 384 citations

Cardiac Hypertrophy Induced by Mitogen-activated Protein Kinase Kinase 7, a Specific Activator for c-Jun NH2-terminal Kinase in Ventricular Muscle Cells

1998 • 335 citations

Cystatin C is a more sensitive marker than creatinine for the estimation of GFR in type 2 diabetic patients

2002 • 290 citations

Bag1–Hsp70 mediates a physiological stress signalling pathway that regulates Raf-1/ERK and cell growth

2001 • 279 citations

Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens.

1989 • 240 citations

Calcineurin and Beyond

2000 • 227 citations

Cloning and Expression of the Rat p8 cDNA, a New Gene Activated in Pancreas during the Acute Phase of Pancreatitis, Pancreatic Development, and Regeneration, and Which Promotes Cellular Growth

1997 • 220 citations

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy.

1998 • 198 citations

Extracellular Signal-regulated Kinase Plays an Essential Role in Hypertrophic Agonists, Endothelin-1 and Phenylephrine-induced Cardiomyocyte Hypertrophy

2000 • 197 citations

Requirement of Phosphatidylinositol 3-Kinase-Dependent Pathway and Src for Gas6-Axl Mitogenic and Survival Activities in NIH 3T3 Fibroblasts

1997 • 191 citations

Regulation of cardiac hypertrophy in vivo by the stress-activated protein kinases/c-Jun NH2-terminal kinases

1999 • 179 citations

Glycogen Synthase Kinase-3 Inhibits the DNA Binding Activity of NFATc

2001 • 161 citations

Identification of a Novel, Putative Rho-specific GDP/GTP Exchange Factor and a RhoA-binding Protein: Control of Neuronal Morphology

1997 • 154 citations

Gene 33/Mig-6, a Transcriptionally Inducible Adapter Protein That Binds GTP-Cdc42 and Activates SAPK/JNK

2000 • 134 citations

Human p8 Is a HMG-I/Y-like Protein with DNA Binding Activity Enhanced by Phosphorylation

2001 • 119 citations

Human myosin-IXb is a mechanochemically active motor and a GAP for rho

1998 • 105 citations

Expression of a novel factor in human breast cancer cells with metastatic potential.

1999 • 104 citations

Activation of phospholipase C beta 4 by heterotrimeric GTP-binding proteins.

1994 • 104 citations

Signalling via stress-activated mitogen-activated protein kinases in the cardiovascular system

2000 • 102 citations

Cloning and expression of the human p8, a nuclear protein with mitogenic activity

1999 • 100 citations

p8-deficient fibroblasts grow more rapidly and are more resistant to adriamycin-induced apoptosis

2002 • 88 citations

Overexpression of p8 Is Inversely Correlated with Apoptosis in Pancreatic Cancer

2001 • 79 citations

Expression of p8 in Human Pancreatic Cancer

2001 • 73 citations

p8 is critical for tumour development induced by ras^V12 mutated protein and E1A oncogene

2002 • 72 citations

Gas6 Induces Growth, β-Catenin Stabilization, and T-Cell Factor Transcriptional Activation in Contact-Inhibited C57 Mammary Cells

2001 • 71 citations

The HMG-I/Y-related Protein p8 Binds to p300 and Pax2trans-Activation Domain-interacting Protein to Regulate thetrans-Activation Activity of the Pax2A and Pax2B Transcription Factors on the Glucagon Gene Promoter

2002 • 69 citations

Forkhead transcription factors are targets of signalling by the proto‐oncogene PKB (C‐AKT)

2000 • 57 citations

Protein Kinase Functions

2000 • 38 citations

Vasoactive agents affect mesangial cell adhesion

1986 • 35 citations

Signaling pathways mediating the response to hypertrophic stress in the heart.

1999 • 31 citations

Mitogen-activated protein kinases and transcriptional responses in renal injury and repair

1998 • 25 citations

Copper/zinc superoxide dismutase mutations and free radical damage in amyotrophic lateral sclerosis.

1995 • 12 citations

Platelet derived growth factor-A chain gene expression in cultured mesangial cells: Regulation by phorbol ester at the level of mRNA abundance, transcription and mRNA stability

1993 • 9 citations

Mammalian MAP kinase pathways

2000 • 7 citations