HLA DQA1-DQB1-TAP2 haplotypes in IDDM families: no evidence for an additional contribution to disease risk by the TAP2 locus

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Analysis of Human Genetic Linkage.

1992 • 1,770 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Association of class I major histocompatibility heavy and light chains induced by viral peptides

1989 • 995 citations

HLA and Disease Associations

1985 • 893 citations

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters

1990 • 717 citations

Analysis of Human Genetic Linkage.

1987 • 709 citations

A Molecular Basis for MHC Class II—Associated Autoimmunity

1988 • 707 citations

The class II molecules of the human and murine major histocompatibility complex

1984 • 664 citations

A gene in the human major histocompatibility complex class II region controlling the class I antigen presentation pathway

1990 • 644 citations

Map of the human MHC

1993 • 585 citations

Selective and ATP-Dependent Translocation of Peptides by the MHC-Encoded Transporter

1993 • 556 citations

Analysis of Human Genetic Linkage

1992 • 555 citations

MHC Class-II Molecules and Autoimmunity

1991 • 521 citations

MHC class II region encoding proteins related to the muKidrug resistance family of transmembrane transporters

1990 • 426 citations

Incidence of childhood-onset insulin-dependent diabetes mellitus: the EURODIAB ACE study

1992 • 414 citations

Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study.

1988 • 387 citations

An essential role for HLA–DM in antigen presentation by class II major histocompatibility molecules

1994 • 378 citations

Analysis of HLA-DQ Genotypes and Susceptibility in Insulin-Dependent Diabetes Mellitus

1990 • 335 citations

A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus.

1990 • 332 citations

Presentation of viral antigen by MHC class I molecules is dependent on a putative peptide transporter heterodimer

1992 • 322 citations

HLA-DMA and DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells

1994 • 247 citations

Allelic variants of the human putative peptide transporter involved in antigen processing.

1992 • 235 citations

Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2

1993 • 217 citations

Location of MHC-encoded transporters in the endoplasmic reticulum and cis-Golgi

1992 • 208 citations

Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ beta chain.

1990 • 195 citations

Statistical properties of the haplotype relative risk

1989 • 169 citations

Use of pooled DNA samples to detect linkage disequilibrium of polymorphic restriction fragments and human disease: studies of the HLA class II loci.

1985 • 160 citations

An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes

1992 • 133 citations

HLA DISEASE ASSOCIATIONS: Models for Insulin Dependent Diabetes Mellitus and the Study of Complex Human Genetic Disorders

1988 • 94 citations

Linkage disequilibrium between TAP2 variants and HLA class II alleles; no primary association between TAP2 variants and insulin‐dependent diabetes mellitus

1993 • 90 citations

Protection from insulin‐dependent diabetes mellitus is linked to a peptide transporter gene

1993 • 76 citations

TAP1 alleles in insulin-dependent diabetes mellitus: a newly defined centromeric boundary of disease susceptibility.

1993 • 68 citations

HLA-DQ rather than HLA-DR region might be involved in dominant nonsusceptibility to diabetes.

1988 • 50 citations

Insulin‐dependent diabetes mellitus and the major histocompatibility complex peptide transporters TAP1 and TAP2: no association in a population with a high disease incidence

1994 • 34 citations

Susceptibility to insulin‐dependent diabetes mellitus and short cytoplasmic ATP‐binding domain TAP2*01 alleles

1994 • 22 citations

Linkage disequilibrium in the insulin gene region: size variation at the 5' flanking polymorphism and bimodality among "class I" alleles.

1994 • 13 citations