A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus.

Structure of the human class I histocompatibility antigen, HLA-A2

1987 • 3,453 citations

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

1987 • 2,403 citations

HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1987 • 2,045 citations

Analysis of enzymatically amplified β-globin and HLA-DQα DNA with allele-specific oligonucleotide probes

1986 • 1,863 citations

A hypothetical model of the foreign antigen binding site of Class II histocompatibility molecules

1988 • 1,161 citations

Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

1988 • 378 citations

Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells

1987 • 367 citations

The genetic susceptibility to type 1 (insulin-dependent) diabetes: Analysis of the HLA-DR association

1983 • 251 citations

Genetic Complexity and Expression of Human Class II Histocompatibility Antigens

1985 • 247 citations

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping

1989 • 238 citations

The significance of the concordance rate for Type 1 (insulin-dependent) diabetes in identical twins

1988 • 220 citations

Description of the Reference Panel of B-Lymphoblastoid Cell Lines for Factors of the HLA System: The B-Cell Line Panel Designed for the Tenth International Histocompatibility Workshop

1989 • 187 citations

Sequence polymorphism of HLA DRβ1 alleles relating to T-cell-recognized determinants

1985 • 183 citations

Transcomplementation of HLA Genes in IDDM: HLA-DQ α and β-Chains Produce Hybrid Molecules in DR3/4 Heterozygotes

1987 • 158 citations

Molecular cloning of a polymorphic DNA endonuclease fragment associates insulin-dependent diabetes mellitus with HLA-DQ.

1987 • 115 citations

Hybrid HLA-DC antigens provide molecular evidence for gene trans-complementation

1984 • 105 citations

Only one DQ-beta restriction fragment pattern of each DR specificity is associated with insulin-dependent diabetes.

1986 • 100 citations

HLA-DR typing in identical twins with insulin-dependent diabetes: difference between concordant and discordant pairs.

1983 • 90 citations

Nomenclature for Factors of the HLA System, 1990

1991 • 48 citations

Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to Type 1 (insulin-dependent) diabetes mellitus

1988 • 32 citations

Study of cis and trans interactions between extended HLA‐haplotypes in insulin‐dependent diabetes

1988 • 22 citations

Significance of the HLA molecular structure to transplantation.

1988 • 15 citations

The HLA-DQB1 Gene Contributes to the Genetic Susceptibility to Insulin-Dependent Diabetes Mellitus

1989 • 2 citations