Mapping of transcription factor binding regions in mammalian cells by ChIP: Comparison of array- and sequencing-based technologies

Genome sequencing in microfabricated high-density picolitre reactors

2005 • 7,594 citations

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

2007 • 5,117 citations

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

2005 • 4,388 citations

STATs: transcriptional control and biological impact

2002 • 3,050 citations

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells

2006 • 2,414 citations

The ENCODE (ENCyclopedia Of DNA Elements) Project

2004 • 2,327 citations

Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

2006 • 2,241 citations

Use of a cDNA microarray to analyse gene expression patterns in human cancer

1996 • 2,002 citations

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

2005 • 1,497 citations

Kinetics of renaturation of DNA

1968 • 1,446 citations

The UCSC Genome Browser Database: update 2006

2005 • 1,385 citations

Accurate Multiplex Polony Sequencing of an Evolved Bacterial Genome

2005 • 1,373 citations

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

2004 • 1,293 citations

Applied bioinformatics for the identification of regulatory elements

2004 • 1,210 citations

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

2006 • 1,137 citations

E2F integrates cell cycle progression with DNA repair, replication, and G₂/M checkpoints

2002 • 1,102 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

A Concise Guide to cDNA Microarray Analysis

2000 • 964 citations

A high-resolution map of active promoters in the human genome

2005 • 922 citations

BIOPROSPECTOR: DISCOVERING CONSERVED DNA MOTIFS IN UPSTREAM REGULATORY REGIONS OF CO-EXPRESSED GENES

2000 • 851 citations

Defining the CREB Regulon

2004 • 708 citations

An algorithm for finding protein–DNA binding sites with applications to chromatin- immunoprecipitation microarray experiments

2002 • 692 citations

The value of prior knowledge in discovering motifs with MEME.

1995 • 673 citations

ChIP-chip: considerations for the design, analysis, and application of genome-wide chromatin immunoprecipitation experiments

2004 • 609 citations

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

2002 • 449 citations

Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

2005 • 445 citations

Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters

2001 • 387 citations

Gene Expression Analysis Using Oligonucleotide Arrays Produced by Maskless Photolithography

2002 • 356 citations

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

2002 • 352 citations

Unbiased location analysis of E2F1-binding sites suggests a widespread role for E2F1 in the human genome

2006 • 307 citations

Distribution of NF-κB-binding sites across human chromosome 22

2003 • 302 citations

The transcriptional activity of human Chromosome 22

2003 • 293 citations

The Race for the $1000 Genome

2006 • 263 citations

Gene identification signature (GIS) analysis for transcriptome characterization and genome annotation

2005 • 243 citations

Genome-Wide Analysis of Menin Binding Provides Insights into MEN1 Tumorigenesis

2006 • 218 citations

CREB Binds to Multiple Loci on Human Chromosome 22

2004 • 172 citations

GATA-1 binding sites mapped in the β-globin locus by using mammalian chIp-chip analysis

2002 • 156 citations

Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation

2004 • 146 citations

High-resolution mapping of DNA copy alterations in human chromosome 22 using high-density tiling oligonucleotide arrays

2006 • 144 citations

ChIP-chip Comes of Age for Genome-wide Functional Analysis

2006 • 143 citations

T-bet Binding to Newly Identified Target Gene Promoters Is Cell Type-independent but Results in Variable Context-dependent Functional Effects

2006 • 132 citations

Identification of the mismatch repair genes PMS2 and MLH1 as p53 target genes by using serial analysis of binding elements

2005 • 111 citations

Global changes in STAT target selection and transcription regulation upon interferon treatments

2005 • 106 citations

Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

2004 • 104 citations

Chromatin Immunoprecipitation (ChIP) on Chip Experiments Uncover a Widespread Distribution of NF-Y Binding CCAAT Sites Outside of Core Promoters

2005 • 93 citations

Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays

2005 • 80 citations

STAT proteins: Signal tranducers and activators of transcription

2001 • 65 citations

Probing Chromatin Immunoprecipitates with CpG-Island Microarrays to Identify Genomic Sites Occupied by DNA-Binding Proteins

2003 • 61 citations

Design optimization methods for genomic DNA tiling arrays

2005 • 54 citations

Tilescope: online analysis pipeline for high-density tiling microarray data

2007 • 50 citations

A Chromatin Immunoprecipitation Screen Reveals Protein Kinase Cβ as a Direct RUNX1 Target Gene

2004 • 45 citations

ExpressYourself: a modular platform for processing and visualizing microarray data

2003 • 40 citations

Assessing the performance of different high-density tiling microarray strategies for mapping transcribed regions of the human genome

2006 • 33 citations