Chromatin immunoprecipitation microarrays for identification of genes silenced by histone H3 lysine 9 methylation

Translating the Histone Code

2001 • 9,488 citations

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

2003 • 6,017 citations

Lanthanum Chloride Inhibits LPS Mediated Expressions of Pro-Inflammatory Cytokines and Adhesion Molecules in HUVECs: Involvement of NF-κB-Jmjd3 Signaling

2017 • 5,610 citations

Cancer-epigenetics comes of age

1999 • 2,379 citations

Alterations in DNA Methylation: A Fundamental Aspect of Neoplasia

1997 • 1,960 citations

The Role of DNA Methylation in Mammalian Epigenetics

2001 • 1,956 citations

High sensitivity mapping of methylated cytosines

1994 • 1,863 citations

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

2001 • 997 citations

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

2002 • 864 citations

The many faces of histone lysine methylation

2002 • 819 citations

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies

2003 • 796 citations

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

2001 • 590 citations

Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.

1999 • 475 citations

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

2002 • 449 citations

Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene

2003 • 420 citations

Histone H3-lysine 9 methylation is associated with aberrant gene silencing in cancer cells and is rapidly reversed by 5-aza-2'-deoxycytidine.

2002 • 383 citations

Critical Role of Histone Methylation in Tumor Suppressor Gene Silencing in Colorectal Cancer

2002 • 352 citations

Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.

2002 • 351 citations

All in the Family: the BTB/POZ, KRAB, and SCAN Domains

2001 • 338 citations

Methylation profiling in acute myeloid leukemia

2001 • 329 citations

Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer

2003 • 319 citations

Methylation and silencing of the Thrombospondin-1 promoter in human cancer

1999 • 172 citations

Triple analysis of the cancer epigenome: an integrated microarray system for assessing gene expression, DNA methylation, and histone acetylation.

2003 • 140 citations

Enrichment for Histone H3 Lysine 9 Methylation at Alu Repeats in Human Cells

2003 • 122 citations

Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ

2000 • 99 citations

Applications of CpG Island Microarrays for High-Throughput Analysis of DNA Methylation

2002 • 81 citations

Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma.

2002 • 68 citations

Gene-targeting reveals physiological roles and complex regulation of the phosphoinositide 3-kinases

2003 • 32 citations