Neonatal Iron Treatment Increases Apoptotic Markers in Hippocampal and Cortical Areas of Adult Rats
Data up to Jan 2025
Total Citations Per Year
Abstract
References (57)
The Rat Brain in Stereotaxic Coordinates
1982 • 53,055 citations
The rat brain in stereotaxic coordinates
1983 • 28,962 citations
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 • 2,796 citations
Apoptosis in the nervous system
2000 • 1,850 citations
Iron, brain ageing and neurodegenerative disorders
2004 • 1,737 citations
Apoptosis in neurodegenerative disorders
2000 • 1,542 citations
Hippocampus
2004 • 1,342 citations
Life and Death of Neurons in the Aging Brain
1997 • 1,323 citations
ALTERATIONS IN THE LEVELS OF IRON, FERRITIN AND OTHER TRACE METALS IN PARKINSON'S DISEASE AND OTHER NEURODEGENERATIVE DISEASES AFFECTING THE BASAL GANGLIA
1991 • 1,012 citations
Apoptosis and Caspases in Neurodegenerative Diseases
2003 • 852 citations
Free radicals and aging
2004 • 658 citations
Apoptosis in Parkinson's disease: Signals for neuronal degradation
2003 • 386 citations
Iron, neuromelanin and ferritin content in the substantia nigra of normal subjects at different ages: consequences for iron storage and neurodegenerative processes
2001 • 381 citations
The possible role of iron in the etiopathology of parkinson's disease
1993 • 303 citations
Caspases: opening the boxes and interpreting the arrows
2002 • 275 citations
Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease
1998 • 269 citations
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection
2003 • 265 citations
Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells.
1994 • 229 citations
Developmental changes in transferrin and iron uptake by the brain in the rat
1990 • 219 citations
Hallervorden-Spatz Syndrome and Brain Iron Metabolism
1991 • 197 citations
Brain iron deposition and the free radical-mitochondrial theory of ageing
2004 • 171 citations
Apoptosis in dopaminergic neurons of the human substantia nigra during normal aging.
1997 • 149 citations
Transferrin and Iron Uptake by the Brain: Effects of Altered Iron Status
1991 • 146 citations
Caspase-Dependent and -Independent Neuronal Death: Two Distinct Pathways to Neuronal Injury
2005 • 139 citations
The role of transition metals in the pathogenesis of Parkinson's disease
1995 • 135 citations
A histochemical study of iron‐positive cells in the developing rat brain
1995 • 133 citations
Apoptosis by Par-4 in cancer and neurodegenerative diseases
2003 • 130 citations
Recognition memory impairment and brain oxidative stress induced by postnatal iron administration
2005 • 112 citations
Changes in Caspase Expression in Alzheimer's Disease: Comparison with Development and Aging
1999 • 109 citations
The age‐related increase in IL‐1 type I receptor in rat hippocampus is coupled with an increase in caspase‐3 activation
2002 • 108 citations
Reversal of age-related deficits in object recognition memory in rats with l-deprenyl
2005 • 108 citations
Neonatal Iron Exposure Induces Neurobehavioural Dysfunctions in Adult Mice
1999 • 108 citations
Caspases on the brain
2002 • 106 citations
Up-regulation of divalent metal transporter 1 is involved in 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in MES23.5 cells
2008 • 103 citations
An autoradiographic study of the uptake and distribution of iron by the brain of the young rat
1990 • 98 citations
Coenzyme Q<sub>10</sub> Provides Neuroprotection in Iron-Induced Apoptosis in Dopaminergic Neurons
2006 • 96 citations
Prostate Apoptosis Response‐4 Production in Synaptic Compartments Following Apoptotic and Excitotoxic Insults
1999 • 94 citations
Maze learning and motor activity deficits in adult mice induced by iron exposure during a critical postnatal period
2000 • 89 citations
Iron Dysregulation and Neurodegeneration: The Molecular Connection
2006 • 81 citations
Memory deficits in adult rats following postnatal iron administration
2001 • 78 citations
Caspase-cleaved TAR DNA-binding protein-43 is a major pathological finding in Alzheimer's disease
2008 • 77 citations
Aging‐related changes in astrocytes in the rat retina: imbalance between cell proliferation and cell death reduces astrocyte availability
2008 • 75 citations
Prostate Apoptosis Response‐4 Mediates Trophic Factor Withdrawal‐Induced Apoptosis of Hippocampal Neurons
1999 • 69 citations
Neonatal iron exposure induces oxidative stress in adult Wistar rat
2001 • 66 citations
Par-4: An Emerging Pivotal Player in Neuronal Apoptosis and Neurodegenerative Disorders
1999 • 63 citations
Apoptosis and Oxidative Stress in the Aging Brain
1996 • 60 citations
Amelioration of recognition memory impairment associated with iron loading or aging by the type 4-specific phosphodiesterase inhibitor rolipram in rats
2008 • 57 citations
Iron as the malignant spirit in successful ageing
2002 • 51 citations
Selegiline protects against recognition memory impairment induced by neonatal iron treatment
2005 • 48 citations
Regulation of Synaptic Function by Neurotrophic Factors in Vertebrates and Invertebrates: Implications for Development and Learning
1999 • 46 citations
Desferoxamine reverses neonatal iron-induced recognition memory impairment in rats
2007 • 44 citations
Evidence for DNA fragmentation in the CNS of aged Fischer-344 rats
1996 • 39 citations
Apoptotic proteins in the course of aging of central nervous system in the rat
2003 • 24 citations
Identification of high caspase-3 mRNA expression as a unique signature profile for extremely old individuals
2002 • 22 citations
Effects of Increased Iron Intake During the Neonatal Period on the Brain of Adult AβPP/PS1 Transgenic Mice
2010 • 20 citations
Par-4 is a synaptic protein that regulates neurite outgrowth by altering calcium homeostasis and transcription factor AP-1 activation
2001 • 18 citations
Iron-dependent enzymes in Parkinson's disease.
1995 • 17 citations