Monoclonal antibody characterization of two distant sites required for function of the central cell-binding domain of fibronectin in cell adhesion, cell migration, and matrix assembly.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

“Western Blotting”: Electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A

1981 • 8,657 citations

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

VLA Proteins in the Integrin Family: Structures, Functions, and Their Role on Leukocytes

1990 • 1,592 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

Elevated levels of the α5β1 fibronectin receptor suppress the transformed phenotype of Chinese hamster ovary cells

1990 • 746 citations

Variants of the cell recognition site of fibronectin that retain attachment-promoting activity.

1984 • 685 citations

Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene.

1985 • 659 citations

Analysis of fibronectin receptor function with monoclonal antibodies: roles in cell adhesion, migration, matrix assembly, and cytoskeletal organization.

1989 • 627 citations

Dualistic nature of adhesive protein function: fibronectin and its biologically active peptide fragments can autoinhibit fibronectin function.

1984 • 465 citations

Receptor functions for the integrin VLA-3: fibronectin, collagen, and laminin binding are differentially influenced by Arg-Gly-Asp peptide and by divalent cations.

1991 • 447 citations

Location of the cell-attachment site in fibronectin with monoclonal antibodies and proteolytic fragments of the molecule

1981 • 444 citations

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion.

1986 • 442 citations

Biologically active synthetic peptides as probes of embryonic development: a competitive peptide inhibitor of fibronectin function inhibits gastrulation in amphibian embryos and neural crest cell migration in avian embryos.

1984 • 429 citations

Adhesion and cytoskeletal organisation of fibroblasts in response to fibronectin fragments.

1986 • 429 citations

Site-directed mutagenesis of the cell-binding domain of human fibronectin: Separable, synergistic sites mediate adhesive function

1988 • 372 citations

Rapid methods for isolation of human plasma fibronectin

1982 • 313 citations

Cytoadhesins, Integrins, and Platelets

1988 • 306 citations

Cell surface receptors for extracellular matrix components

1990 • 297 citations

Fibronectin's cell-adhesive domain and an amino-terminal matrix assembly domain participate in its assembly into fibroblast pericellular matrix.

1987 • 255 citations

The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line.

1990 • 251 citations

Extracellular Matrix Assembly

1988 • 250 citations

Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin (alpha 5 beta 1) antibodies.

1990 • 231 citations

Effects of Modifications of the RGD Sequence and Its Context on Recognition by the Fibronectin Receptor

1989 • 213 citations

Attachment, spreading and locomotion of avian neural crest cells are mediated by multiple adhesion sites on fibronectin molecules.

1988 • 206 citations

The rapid determination of binding constants for antiviral antibodies by a radioimmunoassay. An analysis of the interaction between hybridoma proteins and influenza virus

1979 • 187 citations

Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis

1987 • 184 citations

Monoclonal antibody and synthetic peptide inhibitors of human tumor cell migration.

1990 • 176 citations

Domain structure of the carboxyl-terminal half of human plasma fibronectin.

1983 • 176 citations

The interaction of fibronectin fragments with fibroblastic cells.

1985 • 168 citations

Alignment of biologically active domains in the fibronectin molecule.

1981 • 162 citations

The fibronectin receptor is organized by extracellular matrix fibronectin: implications for oncogenic transformation and for cell recognition of fibronectin matrices.

1989 • 150 citations

Isolation and biological characterization of active fragments of the adhesive glycoprotein fibronectin

1979 • 148 citations

RGD-independent cell adhesion to the carboxy-terminal heparin-binding fragment of fibronectin involves heparin-dependent and -independent activities.

1990 • 131 citations

A comparison of the migration patterns of normal and malignant cells in two assay systems.

1978 • 113 citations

Fibronectins: structure, functions and receptors

1989 • 113 citations

Substratum contacts and cytoskeletal reorganization of BALB/c 3T3 cells on a cell-binding fragment and heparin-binding fragments of plasma fibronectin

1986 • 111 citations

Fibroblast adhesion to RGDS shows novel features compared with fibronectin.

1987 • 85 citations

Elution of fibronectin proteolytic fragments from a hydroxyapatite chromatography column. A simple procedure for the purification of fibronectin domains

1985 • 79 citations

Fibronectin in Health and Disease

2018 • 68 citations

Mechanism of fibronectin-mediated cell migration: Dependence or independence of cell migration susceptibility on RGDS-directed receptor (integrin)

1989 • 61 citations

Purification and complete primary structures of the heparin-, cell-, and DNA-binding domains of bovine plasma fibronectin

1986 • 57 citations

Role of type III homology repeats in cell adhesive function within the cell-binding domain of fibronectin.

1991 • 56 citations

Modulation of matrix adhesive responses of human neuroblastoma cells by neighboring sequences in the fibronectins.

1988 • 48 citations

Fibronectin

1987 • 38 citations

Isolation and characterization of two monoclonal antibodies that recognize remote epitopes on the cell-binding domain of human fibronectin

1989 • 32 citations

Newt epidermal cell migration in vitro and in vivo appears to involve Arg-Gly-Asp-Ser receptors

1987 • 31 citations

Migration of chick blastoderm under the vitelline membrane: The role of fibronectin

1990 • 18 citations

Requirement for two different cell-binding domains in fibronectin for neurite extension of neuronal derivative cells

1990 • 18 citations

Target size for a fibronectin-cell adhesion system determined by the X-ray inactivation method.

1991 • 1 citations