Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis

Integrins: A family of cell surface receptors

1987 • 4,322 citations

Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

1984 • 3,580 citations

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

The pathogenesis of cancer metastasis

1980 • 1,750 citations

The human insulin receptor cDNA: The structural basis for hormone-activated transmembrane signalling

1985 • 1,485 citations

Arg-Gly-Asp: A versatile cell recognition signal

1986 • 1,413 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

The human LDL receptor: A cysteine-rich protein with multiple Alu sequences in its mRNA

1984 • 1,386 citations

Fibronectins: multifunctional modular glycoproteins.

1982 • 1,334 citations

Interaction of plasma membrane fibronectin receptor with talin—a transmembrane linkage

1986 • 1,206 citations

CELL SURFACE INTERACTIONS WITH EXTRACELLULAR MATERIALS

1983 • 1,147 citations

Identification and isolation of a 140 kd cell surface glycoprotein with properties expected of a fibronectin receptor

1985 • 1,119 citations

Cell biology of extracellular matrix

1992 • 1,042 citations

Tumor invasion and the extracellular matrix.

1983 • 960 citations

Platelet Membrane Glycoprotein IIb/IIIa: Member of a Family of Arg-Gly-Asp—Specific Adhesion Receptors

1986 • 945 citations

Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin

1986 • 854 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Identification of an amino acid sequence in laminin mediating cell attachment, chemotaxis, and receptor binding

1987 • 677 citations

Increased permeability of the glomerular basement membrane to ferritin after removal of glycosaminoglycans (heparan sulfate) by enzyme digestion.

1980 • 650 citations

A Synthetic Peptide from Fibronectin Inhibits Experimental Metastasis of Murine Melanoma Cells

1986 • 634 citations

Molecular Biology of Fibronectin

1985 • 608 citations

Cloning of the $beta; subunit of the leukocyte adhesion proteins: Homology to an extracellular matrix receptor defines a novel supergene family

1987 • 520 citations

Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression.

1987 • 508 citations

The cell substrate attachment (CSAT) antigen has properties of a receptor for laminin and fibronectin.

1985 • 503 citations

Platelets have more than one binding site for von Willebrand factor.

1983 • 459 citations

Identification of an alternatively spliced site in human plasma fibronectin that mediates cell type-specific adhesion.

1986 • 442 citations

An interaction between vinculin and talin

1984 • 442 citations

Isolation of a cell surface receptor protein for laminin from murine fibrosarcoma cells.

1983 • 441 citations

Adhesion and cytoskeletal organisation of fibroblasts in response to fibronectin fragments.

1986 • 429 citations

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

1985 • 426 citations

Isolation of a tumor cell laminin receptor

1983 • 426 citations

Microinjection and localization of a 130K protein in living fibroblasts: a relationship to actin and fibronectin

1980 • 406 citations

Membrane-cytoskeleton interaction

1983 • 389 citations

Identification of membrane proteins mediating the interaction of human platelets

1980 • 383 citations

Characterization of the cell surface heterodimer VLA-4 and related peptides.

1987 • 340 citations

Role of laminin in the attachment and metastasis of murine tumor cells.

1982 • 334 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

Physiology of Fibronectin

1984 • 322 citations

Modulation of Cell Adhesion during Induction, Histogenesis, and Perinatal Development of the Nervous System

1984 • 316 citations

A monoclonal antibody detaches embryonic skeletal muscle from extracellular matrices.

1982 • 310 citations

Cell adhesion and migration in the early vertebrate embryo: location and possible role of the putative fibronectin receptor complex

1986 • 309 citations

Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures.

1980 • 306 citations

Detachment of cells from culture substrate by soluble fibronectin peptides.

1985 • 301 citations

Specific and saturable binding of plasma fibronectin to thrombin-stimulated human platelets.

1981 • 300 citations

Distribution of the cell substratum attachment (CSAT) antigen on myogenic and fibroblastic cells in culture.

1985 • 293 citations

The interaction of plasma fibronectin with fibroblastic cells in suspension.

1985 • 266 citations

Cell surface molecules and tumor metastasis

1984 • 262 citations

Interaction of fibronectin with its receptor on platelets

1985 • 251 citations

The role of cell adhesion proteins?laminin and fibronectin?in the movement of malignant and metastatic cells

1985 • 236 citations

Selective Inhibition of Fibronectin-Mediated Cell Adhesion by Monoclonal Antibodies to a Cell-Surface Glycoprotein

1985 • 217 citations

Monoclonal Antibodies Which Alter the Morphology of Cultured Chick Myogenic Cells

1982 • 212 citations

Fibroblast receptor for cell-substratum adhesion: studies on the interaction of baby hamster kidney cells with latex beads coated by cold insoluble globulin (plasma fibronectin).

1980 • 194 citations

Laminin molecular domains which alter metastasis in a murine model.

1984 • 187 citations

Isolation of human serum spreading factor.

1983 • 183 citations

Isolation of a subunit of laminin and its role in molecular structure and tumor cell attachment.

1982 • 182 citations

Domain structure of vitronectin. Alignment of active sites.

1984 • 181 citations

The fibronectin receptor on mammalian erythroid precursor cells: characterization and developmental regulation.

1986 • 180 citations

The cell attachment domain of fibronectin. Determination of the primary structure.

1982 • 177 citations

Recent advances in research on fibronectin and other cell attachment proteins

1985 • 177 citations

Generation of phenotypic diversity and progression in metastatic tumor cells

1984 • 176 citations

Very late activation antigens on rheumatoid synovial fluid T lymphocytes. Association with stages of T cell activation.

1986 • 174 citations

Cell Migration in the Vertebrate Embryo: Role of Cell Adhesion and Tissue Environment in Pattern Formation

1985 • 174 citations

Different mechanisms in the attachment of cells to native and denatured collagen

1979 • 173 citations

Sequencing of laminin B chain cDNAs reveals C-terminal regions of coiled-coil alpha-helix.

1984 • 169 citations

Characterization of protease-resistant fragments of laminin mediating attachment and spreading of rat hepatocytes.

1983 • 161 citations

Integrin (the CSAT antigen): functionality requires oligomeric integrity.

1986 • 160 citations

Synthetic peptides competitively inhibit both direct binding to fibroblasts and functional biological assays for the purified cell-binding domain of fibronectin.

1985 • 148 citations

A monoclonal antibody identifies a glycoprotein complex involved in cell-substratum adhesion

1985 • 136 citations

The cell in contact: Adhesions and junctions as morphogenetic determinants

1986 • 136 citations

Phosphorylation and transformation sensitivity of a major collagen-binding protein of fibroblasts.

1986 • 136 citations

Regulation of fibronectin receptor distribution by transformation, exogenous fibronectin, and synthetic peptides.

1986 • 128 citations

p150,95, the third member of the Mac-1, LFA-1 human leukocyte adhesion glycoprotein family.

1986 • 125 citations

Cellular adhesion, invasion and metastasis

1984 • 119 citations

cDNA sequences from the alpha subunit of the fibronectin receptor predict a transmembrane domain and a short cytoplasmic peptide.

1986 • 115 citations

Fibronectin-plasma membrane interaction in the adhesion of hemopoietic cells.

1986 • 115 citations

Communication between receptors for different ligands on a single cell: ligation of fibronectin receptors induces a reversible alteration in the function of complement receptors on cultured human monocytes.

1984 • 112 citations

Substratum contacts and cytoskeletal reorganization of BALB/c 3T3 cells on a cell-binding fragment and heparin-binding fragments of plasma fibronectin

1986 • 111 citations

Amino acid sequence specificities of an adhesive recognition signal

1985 • 106 citations

Tumor cell diversity and host responses in cancer metastasis—Part I—Properties of metastatic cells

1982 • 103 citations

Cleavage of a 135 kD cell surface glycoprotein correlates with loss of fibroblast adhesion to fibronectin

1985 • 100 citations

Loss of Adhesion of Murine Erythroleukemia Cells to Fibronectin During Erythroid Differentiation

1984 • 100 citations

Characterization of a membrane‐associated glycoprotein complex implicated in cell adhesion to fibronectin

1985 • 97 citations

Expression of preprosomatostatin in heterologous cells: Biosynthesis, posttranslational processing, and secretion of mature somatostatin

1984 • 96 citations

Studies on the function of cell surface glycoproteins. I. Use of antisera to surface membranes in the identification of membrane components relevant to cell-substrate adhesion.

1979 • 96 citations

Monoclonal antibodies to the human laminin receptor recognize structurally distinct sites

1985 • 89 citations

Fibronectin-mediated binding and phagocytosis of polystyrene latex beads by baby hamster kidney cells.

1983 • 85 citations

The IIb-IIIa glycoprotein complex that mediates platelet aggregation is directly implicated in leukocyte adhesion

1986 • 83 citations

Expression and function of a putative cell surface receptor for fibronectin in hamster and human cell lines.

1986 • 81 citations

A 135000 molecular weight plasma membrane glycoprotein involved in fibronectin-mediated cell adhesion

1986 • 79 citations

Adhesive multiplicity in the interaction of embryonic fibroblasts and myoblasts with extracellular matrices.

1984 • 74 citations

New surface component of fibroblast's focal contacts identified by a monoclonal antibody

1982 • 69 citations

Detection of a cell-surface antigen correlated with organ-specific metastasis

1980 • 67 citations

Collagen can modulate cell interactions with fibronectin.

1985 • 63 citations

Involvement of cell-cell adhesion molecules in liver colonization by metastatic murine lymphoma/lymphosarcoma variants

1984 • 46 citations

Cell configuration and adhesive properties of metastasizing and non-metastasizing BSp73 rat adenocarcinoma cells

1986 • 46 citations

Two distinct mechanisms of fibroblast adhesion

1981 • 41 citations

Tissue-specific modulation of a set of related cell surface antigens in Drosophila

1985 • 41 citations

Monoclonal antibodies NORM-1 and NORM-2 induce more normal behavior of tumor cells in vitro and reduce tumor growth in vivo

1985 • 38 citations

Multiple phenotypic divergence of mammary adenocarcinoma cell clones

1984 • 37 citations

Subpopulations of liver coated vesicles resolved by preparative agarose gel electrophoresis.

1986 • 37 citations

Differentiation stimuli induce receptors for plasma fibronectin on the human myelomonocytic cell line HL-60

1984 • 36 citations

Inhibition of fibronectin receptor function by antibodies against baby hamster kidney cell wheat germ agglutinin receptors.

1982 • 35 citations

Interaction of fibronectin-coated beads with CHO cells

1984 • 29 citations

Studies on the function of cell surface glycoproteins. II. Possible role of surface glycoproteins in the control of cytoskeletal organization and surface morphology.

1979 • 26 citations

Desensitization of the Response of Adenylate Cyclase to Catecholamines

1983 • 26 citations

Cellular behavior of metastatic B16 melanoma in experimental blood-borne implantation and cerebral invasion. An electron microscopic study.

1985 • 26 citations

Two distinct mechanisms for the interaction of cells with fibronectin substrata

1985 • 21 citations

Isolation and characterization of epinectin, a novel adhesion protein for epithelial cells.

1984 • 19 citations

Investigation of Membrane-Located Receptors

1984 • 15 citations

cAMP‐induced phenotypic reversion of adhesion, aggregation, and endocytosis in adhesion‐defective CHO cell variants

1985 • 14 citations

Role of phorbol ester receptors in the 12‐0‐tetradecanoyl‐phorbol‐13‐acetate (TPA)‐induced down‐regulation of colony‐stimulating factor (CSF‐1) binding to murine peritoneal exudate macrophages

1985 • 13 citations

Altered type I protein kinase in adhesion defective CHO cell variants

1987 • 13 citations

Investigation of membrane located receptors

1985 • 4 citations

Fibronectin and anchorage‐independent and anchorage‐dependent growth of benign and malignant cell lines

1983 • 4 citations