Immunologic mechanisms of cutaneous drug reactions

Ciba foundation symposium

1964 • 2,217 citations

Severe Adverse Cutaneous Reactions to Drugs

1994 • 1,523 citations

Medication Use and the Risk of Stevens–Johnson Syndrome or Toxic Epidermal Necrolysis

1995 • 1,415 citations

Tryptase Levels as an Indicator of Mast-Cell Activation in Systemic Anaphylaxis and Mastocytosis

1987 • 775 citations

The incidence of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. A population-based study with particular reference to reactions caused by drugs among outpatients

1990 • 414 citations

Toxic epidermal necrolysis (Lyell syndrome). Incidence and drug etiology in France, 1981-1985

1990 • 398 citations

HYDRALAZINE-INDUCED SYSTEMIC LUPUS ERYTHEMATOSUS: INFLUENCE OF HLA-DR AND SEX ON SUSCEPTIBILITY

1980 • 380 citations

Toxic epidermal necrolysis (Lyell syndrome)

1990 • 378 citations

Activation of drug-specific CD4+ and CD8+ T cells in individuals allergic to sulfonamides, phenytoin, and carbamazepine.

1995 • 351 citations

Immediate hypersensitivity reactions to penicillin and related antibiotics

1988 • 347 citations

Essential flexibility in the T-cell recognition of antigen

1996 • 330 citations

Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis

1996 • 293 citations

Cutaneous late-phase response to allergen. Mediator release and inflammatory cell infiltration.

1989 • 250 citations

Allergy to penicillin with good tolerance to other penicillins; study of the incidence in subjects allergic to betalactams

1990 • 199 citations

Heterogeneous T cell responses to beta-lactam-modified self-structures are observed in penicillin-allergic individuals.

1995 • 196 citations

Regulation of Autoimmune Disease Physiological and Therapeutic

1986 • 190 citations

The role of cytochrome P450 enzymes in hepatic and extrahepatic human drug toxicity

1995 • 152 citations

Adverse effects profile of sulfhydryl compounds in man

1986 • 142 citations

A prospective study of the risk of an immediate adverse reaction to protamine sulfate during cardiopulmonary bypass surgery

1990 • 126 citations

T cell recognition of penicillin G: Structural features determining antigenic specificity

1996 • 125 citations

T Cell Recognition of Haptens, a Molecular View

1994 • 122 citations

Predominance of Epidermal CD8+ T Lymphocytes in Bullous Cutaneous Reactions Caused by β-Lactam Antibiotics

1993 • 120 citations

Association of Antibody to Histone Complex H2A–H2B with Symptomatic Procainamide-Induced Lupus

1988 • 115 citations

New Trends in Allergy II

1986 • 114 citations

Lymphocyte Activation in Cutaneous Drug Reactions

1995 • 106 citations

D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3.

1984 • 104 citations

CD8+ dermal T cells from a sulphamethoxazole-induced bullous exanthem proliferate in response to drug-modified liver microsomes

2006 • 98 citations

Fixed drug eruption. Expression of epidermal keratinocyte intercellular adhesion molecule-1 (ICAM-1)

1989 • 81 citations

Endothelial Barrier Function

1989 • 70 citations

Sulfonamide-reactive lymphocytes detected at very low frequency in the peripheral blood of patients with drug-induced eruptions

1994 • 59 citations

T cell reactivity to penicillin: Phenotypic analysis of in vitro activated cell subsets

1986 • 57 citations

Induction of Acantholysis in Organ Explant Culture by Penicillamine and Captopril

1989 • 53 citations

Fixed Drug Eruption

1989 • 53 citations

Drug-specific T cells derived from patients with drug-induced allergic hepatitis.

1992 • 52 citations

Principles and practice of immunotoxicology

1992 • 47 citations

Drug allergy: An overview

1986 • 45 citations

Molecular genetics and the future of pharmacogenetics

1990 • 35 citations

Drug-induced pemphigus.

1989 • 25 citations

Lymphocyte Activation in Cutaneous Drug Reactions.

1995 • 22 citations

IgE, Mast Cells and the Allergic Response

1990 • 22 citations

Principles and Practice of Immunotoxicology

1991 • 21 citations

Pharmacogenetic Perspectives: Genes, Drugs and Disease

1984 • 21 citations

Single doses of intravenous protamine result in the formation of protamine-specific IgE and IgG antibodies

1996 • 19 citations

The Receptor with High Affinity for IgE

2007 • 16 citations

Pemphigus-like eruption induced by d-penicillamine and captopril, in the same patient.

1988 • 14 citations

Lichenoid dermatoses and related disorders. I. Lichen planus and Lichenoid drug-induced eruptions

1990 • 14 citations

Drug Metabolism and Drug Allergy

1991 • 10 citations

Fortschritte der Dermatologie

1889 • 8 citations

Allergische Arzneimittelreaktionen der Haut^*

2008 • 6 citations

Schwere arzneimittelinduzierte Hautreaktionen: Pemphigus vulgaris, bullöses Pemphigoid, generalized bullous fixed drug eruption, Erythema exsudativum multiforme majus, Stevens-Johnson-Syndrom und toxisch-epidermale Nekrolyse

1995 • 6 citations

Photobiology 1937–1987

1989 • 5 citations

[Diagnosis and management of drug allergy].

1968 • 3 citations

Arzneimittelallergie

2009 • 3 citations