Regulation of Autoimmune Disease Physiological and Therapeutic

The clonal selection theory of acquired immunity

1959 • 1,576 citations

The rapid isolation of clonable antigen‐specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

1981 • 917 citations

Development of Arthritis, Periarthritis and Periostitis in Rats Given Adjuvants.

1956 • 847 citations

Naturally occurring antibodies against nine common antigens in human sera. I. Detection, isolation and characterization.

1982 • 665 citations

Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic protein

1981 • 520 citations

Arthritis induced by a T-lymphocyte clone that responds to Mycobacterium tuberculosis and to cartilage proteoglycans.

1985 • 463 citations

Lines of T Lymphocytes Induce or Vaccinate Against Autoimmune Arthritis

1983 • 418 citations

Activated T lymphocytes produce a matrix-degrading heparan sulphate endoglycosidase

1984 • 344 citations

Arthritis induced in rats by cloned T lymphocytes responsive to mycobacteria but not to collagen type II.

1984 • 296 citations

T LYMPHOCYTES OF RHEUMATOID ARTHRITIS PATIENTS SHOW AUGMENTED REACTIVITY TO A FRACTION OF MYCOBACTERIA CROSS-REACTIVE WITH CARTILAGE

1986 • 289 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

T lymphocyte line specific for thyroglobulin produces or vaccinates against autoimmune thyroiditis in mice.

1983 • 221 citations

The Genetics of Antibody Diversity

1982 • 214 citations

Autoimmunity: Genetic, Immunologic, Virologic, and Clinical Aspects

1978 • 187 citations

Autoantibodies to Insulin Receptor Spontaneously Develop as Anti-Idiotypes in Mice Immunized with Insulin

1982 • 168 citations

Membrane fluidity in malignancy Adversative and recuperative

1984 • 167 citations

Effector T lymphocyte line cells migrate to the thymus and persist there

1982 • 165 citations

T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis

1985 • 155 citations

T lymphocyte lines producing or vaccinating against autoimmune encephalomyelitis (EAE). Functional activation induces peanut agglutinin receptors and accumulation in the brain and thymus of line cells

1983 • 145 citations

Specificity of T lymphocyte lines for peptides of myelin basic protein.

1985 • 125 citations

Spontaneous remission and acquired resistance to autoimmune encephalomyelitis (EAE) are associated with suppression of T cell reactivity: suppressed EAE effector T cells recovered as T cell lines.

1982 • 121 citations

Experimental models in rheumatoid disease

1964 • 111 citations

Vaccination against autoimmune encephalomyelitis (EAE): Attenuated autoimmune T lymphocytes confer resistance to induction of active EAE but not to EAE mediated by the intact T lymphocyte line

1981 • 108 citations

Antigen-induced inhibition of experimental allergic encephalomyelitis. III. Localization of an inhibitory site distinct from the major encephalitogenic determinant of myelin basic protein.

1975 • 85 citations

Amino Acid Sequences of Insulins

1972 • 80 citations

Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: genotype of antigen-presenting cells influences immunodominant epitope of basic protein.

1986 • 79 citations

Immunospecific inhibition of nerve conduction by T lymphocytes reactive to basic protein of myelin

1983 • 73 citations

Autoimmune encephalomyelitis (EAE) mediated or prevented by T lymphocyte lines directed against diverse antigenic determinants of myelin basic protein. Vaccination is determinant specific.

1983 • 64 citations

Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. I. Characterization of the antibodies.

1984 • 53 citations

T lymphocyte lines induce autoimmune encephalomyelitis, delayed hypersensitivity and bystander encephalitis or arthritis

1984 • 53 citations

Experimental autoimmune encephalomyelitis (EAE) in genetically resistant rats: PVG rats resist active induction of EAE but are susceptible to and can generate EAE effector T cell lines.

1982 • 50 citations

Antibodies to Insulin Receptor Followed by Anti-Idiotype: Antibodies to Insulin in Child With Hypoglycemia

1987 • 48 citations

Mouse antibodies to the insulin receptor developing spontaneously as anti-idiotypes. II. Effects on glucose homeostasis and the insulin receptor.

1984 • 39 citations

Vaccination against Experimental Autoimmune Diseases Using T Lymphocytes Treated with Hydrostatic Pressure

1986 • 33 citations

Various Types of Acquired Resistance to Experimental ‘Allergic’ Encephalomyelitis

1959 • 25 citations

H-2K mutation controls immune response phenotype of autoimmune thyroiditis. Critical expression of mutant gene product in both thymus and thyroid glands.

1980 • 22 citations

Role of the thymus in induction and transfer of vaccination against adjuvant arthritis with a T lymphocyte line in rats.

1985 • 22 citations

Promotion of tumor antigenicity in EL-4 leukemia cells by hydrostatic pressure

1986 • 21 citations

Structural analysis of insulin determinants seen by T cells directed by H-2 genes

1983 • 16 citations

Clinics in immunology and allergy

1984 • 8 citations

Immunization to Insulin Generates Antiidiotypes That Behave as Antibodies to the Insulin Hormone Receptor and Cause Diabetes Mellitus

1984 • 6 citations