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Toxic epidermal necrolysis (Lyell syndrome)

Data up to Jan 2025

Published1990
Citations378
References186

Total Citations Per Year

Abstract

References (186)

Dermatology in General Medicine.

1988 • 1,130 citations

TOXIC-SHOCK SYNDROME ASSOCIATED WITH PHAGE-GROUP-I STAPHYLOCOCCI

1978 • 1,017 citations

Pneumocystis carinii Pneumonia: A Comparison Between Patients with the Acquired Immunodeficiency Syndrome and Patients with Other Immunodeficiencies

1984 • 853 citations

ANGIOTENSIN-CONVERTING ENZYME AND THE COUGH REFLEX

1987 • 744 citations

TOXIC EPIDERMAL NECROLYSIS: AN ERUPTION RESEMBLING SCALDING OF THE SKIN.

1956 • 722 citations

Adverse Reactions to Trimethoprim-Sulfamethoxazole in Patients with the Acquired Immunodeficiency Syndrome

1984 • 702 citations

Toxic-Shock Syndrome in Menstruating Women

1980 • 638 citations

A NEW ERUPTIVE FEVER ASSOCIATED WITH STOMATITIS AND OPHTHALMIA

1922 • 504 citations

Erythema multiforme: A critical review of characteristics, diagnostic criteria, and causes

1983 • 500 citations

Drug-induced cutaneous reactions. A report from the Boston Collaborative Drug Surveillance Program on 15,438 consecutive inpatients, 1975 to 1982

1986 • 474 citations

STERILITY AND TESTICULAR ATROPHY RELATED TO CYCLOPHOSPHAMIDE THERAPY

1972 • 453 citations

Epidermal cell (keratinocyte)-derived thymocyte-activating factor (ETAF).

1981 • 420 citations

Immediate Hypersensitivity Reactions to Beta-Lactam Antibiotics

1987 • 416 citations

The Staphylococcal Scalded-Skin Syndrome

1970 • 414 citations

Toxic epidermal necrolysis. Clinical findings and prognosis factors in 87 patients

1987 • 401 citations

Toxic epidermal necrolysis (Lyell syndrome). Incidence and drug etiology in France, 1981-1985

1990 • 398 citations

Improved Burn Center Survival of Patients with Toxic Epidermal Necrolysis Managed without Corticosteroids

1986 • 391 citations

Differences in Metabolism of Sulfonamides Predisposing to Idiosyncratic Toxicity

1986 • 375 citations

Outpatient Waiting Time

1963 • 371 citations

Drug-Induced Cutaneous Reactions

1986 • 341 citations

Toxic Epidermal Necrolysis (Lyell Syndrome)

1990 • 300 citations

Genetic Susceptibility to Toxic Epidermal Necrolysis

1987 • 267 citations

Interleukin 1 is more than an interleukin

1982 • 257 citations

A REVIEW OF TOXIC EPIDERMAL NECROLYSIS IN BRITAIN

1967 • 252 citations

The Culprit Drugs in 87 Cases of Toxic Epidermal Necrolysis (Lyell's Syndrome)

1987 • 247 citations

Predisposition to Phenytoin Hepatotoxicity Assessed in Vitro

1981 • 235 citations

Toxic epidermal necrolysis (the scalded skin syndrome): A reappraisal

1979 • 232 citations

COMPLICATIONS OF CO-TRIMOXAZOLE IN TREATMENT OF AIDS-ASSOCIATED PNEUMOCYSTIS CARINII PNEUMONIA IN HOMOSEXUAL MEN

1983 • 216 citations

LEWIS BLOOD-TYPE MAY AFFECT THE INCIDENCE OF GASTROINTESTINAL CANCER

1982 • 207 citations

Severe Cutaneous Reactions among American Travelers Using Pyrimethamine-Sulfadoxine (Fansidar®) for Malaria Prophylaxis

1986 • 203 citations

Drug disposition and drug hypersensitivity

1987 • 199 citations

[Acute generalized exanthematic pustuloses (four cases) (author's transl)].

1980 • 192 citations

Toxic Epidermal Necrolysis

1987 • 191 citations

Burns

1985 • 176 citations

Staphylococcal scalded skin syndrome. Clinical features, pathogenesis, and recent microbiological and biochemical developments

1977 • 167 citations

Acute disseminated epidermal necrosis types 1, 2, and 3: Study of sixty cases

1985 • 166 citations

ENERGY REQUIREMENTS OF PREGNANCY IN THE GAMBIA

1987 • 163 citations

Increased Glomerular Filtration Rate in Patients with Major Burns and Its Effect on the Pharmacokinetics of Tobramycin

1978 • 154 citations

Erythema multiforme in children.

1976 • 146 citations

EXPIRATORY BACTERIAL FILTER!

1976 • 145 citations

Plasmapheresis in Severe Drug-Induced Toxic Epidermal Necrolysis

1985 • 130 citations

Cutaneous Manifestations of Graft‐Versus‐Host Disease

1981 • 122 citations

Toxic Epidermal Necrolysis in a Patient With Graft-vs-Host Reaction

1972 • 120 citations

Staphylococcal Scalded Skin Syndrome

1977 • 120 citations

Toxic epidermal necrolysis. Rapid differentiation between staphylococcal- and drug-induced disease

1975 • 120 citations

Etiologic Factors of the Stevens-Johnson Syndrome

1980 • 117 citations

An expanded profile of cutaneous reactions to nonsteroidal anti-inflammatory drugs. Reports to a specialty-based system for spontaneous reporting of adverse reactions to drugs.

1984 • 112 citations

Ocular Aftermath of Stevens-Johnson Syndrome

1973 • 110 citations

Stevens‐Johnson syndrome associated with occupational exposure to trichloroethylene

1984 • 109 citations

D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3.

1984 • 104 citations

Cutaneous and immunologic reactions to phenytoin

1988 • 100 citations

Toxic Epidermal Necrolysis

1984 • 95 citations

Drug‐Induced Toxic Epidermal Necrolysis Treated with Cyclosporin

1989 • 94 citations

Treatment of toxic epidermal necrolysis. Créteil's experience.

1987 • 94 citations

Gastrointestinal involvement complicating Stevens-Johnson syndrome

1986 • 90 citations

Toxic Epidermal Necrolysis

1975 • 90 citations

Dermal and Epidermal Types of Erythema Multiforme

1974 • 89 citations

Improved Treatment of the Stevens-Johnson Syndrome

1984 • 89 citations

DEMONSTRATION OF BASAL CELL IMMUNOFLUORKSCENCE IN DRUG-INDUCED TOXIC EPIDERMAL NECROLYSIS

1972 • 89 citations

An Expanded Profile of Cutaneous Reactions to Nonsteroidal Anti-inflammatory Drugs

1984 • 86 citations

Treatment of Toxic Epidermal Necrolysis

1987 • 83 citations

Toxic Epidermal Necrolysis, Azotemia, and Death After Allopurinol Therapy

1970 • 82 citations

Phenytoin hypersensitivity reaction presenting with toxic epidermal necrolysis and severe hepatitis

1985 • 80 citations

SJÖGREN-LIKE SYNDROME AFTER DRUG-INDUCED TOXIC EPIDERMAL NECROLYSIS

1985 • 79 citations

Toxic Epidermal Necrolysis

1980 • 77 citations

Delayed Hypersensitivity in Ampicillin-Induced Toxic Epidermal Necrolysis

1983 • 77 citations

Drug‐induced Febrile Mucocutaneous Syndrome

1975 • 75 citations

Observations on drug-induced toxic epidermal necrolysis in Singapore

1984 • 74 citations

Lymphocyte Transformation Test in Drug-Induced Toxic Epidermal Necrolysis

1985 • 73 citations

Recent Advances in Dermatology

1990 • 73 citations

Clinical Management: A Burn Center Experience with Toxic Epidermal Necrolysis

1983 • 72 citations

Toxic pustuloderma--a new entity?

1984 • 68 citations

Toxic Epidermal Necrolysis

1987 • 63 citations

Toxic Epidermal Necrolysis

1975 • 63 citations

Acute Generalized Exanthematous Pustular Dermatitis and Viral Infection

1986 • 63 citations

Toxic epidermal necrolysis

2002 • 61 citations

Burn Rounds:Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Pathophysiologic Review with Recommendations for a Treatment Protocol

1983 • 61 citations

Carbamazepine ('Tegretol') and toxic epidermal necrolysis: report of three cases with histopathological observations

1982 • 59 citations

Eruptive Nevocytic Nevi After Severe Bullous Disease

1977 • 58 citations

The expression of PNA-lectin binding sites and S-100 protein in histiocytic lesions of the skin. A comparative immunohistochemical study.

1988 • 58 citations

Burn Unit Management of Toxic Epidermal Necrolysis

1978 • 58 citations

Incidence of circulating antibodies reactive with basal cells of skin in drug reactions.

1974 • 57 citations

Fifteen cases of toxic epidermal necrolysis (Lyell)

1973 • 57 citations

Desensitization to trimethoprim sulfamethoxazole in patients with acquired immune deficiency syndrome and Pneumocystis carinii pneumonia.

1989 • 56 citations

Lymphopenia and abnormal balance of T-lymphocyte subpopulations in toxic epidermal necrolysis

1984 • 55 citations

Fatal Toxic Epidermal Necrolysis Following Reexposure to Phenytoin: A Case Report

1983 • 53 citations

Widespread Bullous Fixed Drug Eruption Mimicking Toxic Epidermal Necrolysis

1988 • 53 citations

Lymphocyte Subsets and Langerhans' Cells in Toxic Epidermal Necrolysis

1986 • 51 citations

Toxic Epidermal Necrolysis and Homologous Disease in Hamsters

1968 • 51 citations

An unusual bullous eruption.

1956 • 51 citations

Hepatitis, toxic epidermal necrolysis and pancreatitis in association with sulindac therapy.

1983 • 50 citations

Toxic Epidermal Necrolysis Associated With Allopurinol Administration

1975 • 50 citations

Cutaneous Reactions to Rheumatological Drugs

1982 • 49 citations

Skin antibodies in bone marrow transplanted patients

1976 • 49 citations

An iatrogenic autoantibody: immunological responses to 'pituitary snuff' in patients with diabetes insipidus.

1966 • 48 citations

Incidence of circulating antibodies reactive with basal cells of skin in drug reactions

1974 • 47 citations

Management of Toxic Epidermal Necrolysis in a Pediatric Burn Center

1985 • 46 citations

Cutaneous immunotorescence study of erythema multiforme: Correlation with light microscopic patterns and etiologic agents

1984 • 46 citations

AN ANALYSIS OF GRAFT-VERSUS-HOST DISEASE IN SYRIAN HAMSTERS

1970 • 46 citations

Methotrexate-induced necrolysis

1983 • 46 citations

Toxic Epidermal Necrolysis with Extensive Mucosal Erosions of the Gastrointestinal and Respiratory Tracts

1986 • 44 citations

Fumigant-Induced Toxic Epidermal Necrolysis

1974 • 43 citations

Asymptomatic hyperuricaemia and allopurinol induced toxic epidermal necrolysis.

1985 • 43 citations

Fatal Toxic Epidermal Necrolysis During Prophylaxis With Pyrimethamine and Sulfadoxine in a Human Immunodeficiency Virus—Infected Person

1988 • 42 citations

Use of Amnion for the Treatment of Stevens-Johnson Syndrome

1986 • 42 citations

Renal disease associated with toxic epidermal necrolysis (Lyell's disease)

1974 • 41 citations

Corticosteroids for Erythema Multiforme?

1989 • 41 citations

Staphylococcal Scalded Skin Syndrome, Toxic Shock Syndrome, and Kawasaki Disease

1983 • 41 citations

GRAFT-VERSUS-HOST REACTION AND TOXIC EPIDERMAL NECROLYSIS

1972 • 40 citations

Haematological disturbances and immune mechanisms in toxic epidermal necrolysis

1986 • 39 citations

Toxic Epidermal Necrolysis From Graft-vs-Host Disease

1978 • 39 citations

Topical tretinoin treatment for severe dry-eye disorders

1986 • 39 citations

DRUG-INDUCED TOXIC EPIDERMAL NECROLYSIS

1985 • 39 citations

Erythema multiforme – Response to Corticosteroid

1984 • 37 citations

The staphylococcal scalded skin syndrome in historical perspective: Emergence of dermopathic strains of Staphylococcus aureus and discovery of the epidermolytic toxin

1983 • 37 citations

Adverse reactions to sulphadoxine-pyrimethamine in Swedish travellers: implications for prophylaxis.

1987 • 37 citations

Mucocutaneous eruptions due to antiepileptic drug therapy in children

1979 • 36 citations

A case of contact dermatitis, erythema multiforme, and toxic epidermal necrolysis

1981 • 35 citations

Staphylococcal Toxin Syndromes

1985 • 35 citations

Toxic Epidermal Necrolysis and Staphylococcal Scalded Skin Syndrome

1983 • 35 citations

Toxic epidermal necrolysis in Stevens--Johnson syndrome.

1978 • 34 citations

Toxic Epidermal Necrolysis Caused by "Gin and Tonic"

1974 • 34 citations

Involvement of macrophages in the pathology of toxic epidermal necrolysis

1985 • 34 citations

Toxic Epidermal Necrolysis in a 6‐week‐old Infant

1985 • 34 citations

Ethambutol-Induced Toxic Epidermal Necrolysis

1981 • 33 citations

Toxic epidermal necrolysis: An approach to management using cryopreserved allograft skin

1987 • 33 citations

Nutritional Considerations for the Burned Patient

1987 • 33 citations

FURTHER EXPERIENCES OF TOXIC EPIDERMAL NECROLYSIS INCRIMINATING ALLOPURINOL, PYRAZOLONE AND DERIVATIVES

1972 • 32 citations

Burn therapy 1985: Acute management

1986 • 32 citations

Toxic epidermal necrolysis occurring during treatment with trimethoprim alone

1988 • 31 citations

Dermal and Epidermal Types of Erythema Multiforme

1975 • 31 citations

Clinical Aspects of Skin Reactions to NSAIDs

1987 • 31 citations

Hyperbaric oxygen treatment of toxic epidermal necrolysis.

1986 • 31 citations

Sulindac-lnduced Stevens-Johnson Toxic Epidermal Necrolysis Syndrome

1980 • 30 citations

Ocular Manifestations of Toxic Epidermal Necrolysis Associated With Allopurinol Use

1977 • 30 citations

Clues to Pathogenesis of Toxic Epidermal Necrolysis

1985 • 29 citations

FLUIDISED-BEAD BED IN THE INTENSIVE-THERAPY UNIT

1980 • 29 citations

Skin reactions to co-trimoxazole

1987 • 29 citations

Universal cutaneous depigmentation following phenytoin-induced toxic epidermal necrolysis

1984 • 29 citations

Nutritional Problems of the Acute and Chronic Burn Patient

1988 • 25 citations

Disseminated intravascular coagulation associated with toxic epidermal necrolysis (Lyell's syndrome)

1979 • 25 citations

Management of Toxic Epidermal Necrolysis

1984 • 24 citations

A CASE OF TOXIC EPIDERMAL NECROLYSIS SECONDARY TO INDOMETHACIN

1983 • 24 citations

Human and murine cutaneous graft-versus-host diseases. Potential models for the study of immunologically mediated skin diseases

1984 • 23 citations

Toxic Epidermal Necrolysis Probably Due to <i>Klebsiella pneumoniae </i>Sepsis

1984 • 23 citations

Esophageal stricture secondary to drug-induced toxic epidermal necrolysis

1984 • 23 citations

Ultrastructure of Eosinophilic Staining Epidermal Cells in Toxic Epidermal Necrolysis and Fixed Drug Eruption

1969 • 22 citations

Junctional naevi following toxic epidermal necrolysis

1978 • 22 citations

TOXIC EPIDERMAL NECROLYSIS AND MALIGNANT LYMPHOMA

1967 • 22 citations

Toxic epidermal necrolysis following bone marrow transplantation.

1984 • 20 citations

Survival after a Second Episode of Toxic Epidermal Necrolysis

1988 • 19 citations

Management of cryptococcosis and toxic epidermal necrolysis in a dog.

1987 • 19 citations

Phenytoin-Induced Toxic Epidermal Necrolysis

1979 • 18 citations

Toxic epidermal necrolysis due to erythromycin

1985 • 17 citations

TOXIC EPIDERMAL NECROLYSIS WITH OPTHALMIC COMPLICATIONS

1964 • 17 citations

Update on the Stevens-Johnson syndrome

1988 • 16 citations

Bullae in a patient with toxic shock syndrome

1984 • 16 citations

Use of an air-fluidized bed in the care of patients with extensive burns

1972 • 16 citations

Toxic epidermal necrolysis provoked by barbiturates*

1973 • 16 citations

Allopurinol‐induced Toxic Epidermal Necrolysis

1984 • 16 citations

[Hematologic anomalies in Lyell's syndrome. Study of 26 cases].

1983 • 16 citations

Contact toxic epidermal necrolysis

1987 • 15 citations

Toxic epidermal necrolysis in a patient affected by mixed essential cryoglobulinemia

1988 • 15 citations

Hypersensitivity reactions to drugs in acquired immunodeficiency syndrome

1987 • 14 citations

Clues to Pathogenesis of Toxic Epidermal Necrolysis

1985 • 14 citations

Long-Term Complications of Toxic Epidermal Necrolysis (Lyell’s Disease)

1987 • 13 citations

Toxic epidermal necrolysis associated with streptococcal septicaemia.

1985 • 13 citations

[Stevens-Johnson syndrome and toxic epidermal necrolysis following intake of sulfonamides].

1982 • 11 citations

Toxic epidermal necrolysis, leucopenia and thrombocytopenic purpura-a further complication of Benoxaprofen therapy

1982 • 10 citations

Pharmacogenetics and Adverse Drug Reactions in the Skin

1983 • 10 citations

[Ocular complications of Lyell's syndrome: recent concepts apropos of 26 cases].

1985 • 9 citations

Exfoliative Dermatitis in an Infant

1983 • 8 citations

[Drug-induced Lyell's syndromes (9 cases)].

1982 • 8 citations

Toxic epidermal necrolysis from oil lamp fuel

1984 • 7 citations

Therapeutic challenge for Isospora belli enteritis in an AIDS patient who developed Lyell syndrome after co-trimoxazole therapy.

1989 • 7 citations

Management of toxic epidermal necrolysis with a hydrogel dressing and fluidized-bead bed: report of three cases

1987 • 7 citations

Toxic Epidermal Necrolysis Complicated by Severe Wound Sepsis

1987 • 7 citations

Granulocytes, Lymphocytes, and Toxic Epidermal Necrolysis

1985 • 7 citations

[23 cases of severe bullous dermatitis medicamentosa with epidermolysis].

1972 • 7 citations

Toxic Epidermal Necrolysis Complicated by Severe Wound Sepsis

1987 • 6 citations

Toxic Epidermal Necrolysis Due to Cephem

1988 • 6 citations

[Toxic epidermal necrolysis in children (Lyell's syndrome). Apropos of 18 cases].

1987 • 5 citations

Fatal toxic epidermal necrolysis associated with Hodgkin's disease.

1985 • 5 citations

[Toxic epidermic necrolysis in acute disseminated lupus erythematosus].

1980 • 4 citations

Drug Monitoring in Dermatology

1986 • 3 citations

Dermatologic Emergencies

1986 • 2 citations

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Toxic epidermal necrolysis (Lyell syndrome) (1990) – Journal of the American Academy of Dermatology | Metascience Observatory Explorer