A prospective study of the risk of an immediate adverse reaction to protamine sulfate during cardiopulmonary bypass surgery

Complement and the damaging effects of cardiopulmonary bypass

1983 • 1,360 citations

Complement Activation during Cardiopulmonary Bypass

1981 • 1,163 citations

Protamine: a review of its toxicity.

1985 • 335 citations

Complement activation and neutropenia occurring during cardiopulmonary bypass

1981 • 324 citations

Protamine

1985 • 275 citations

Effects of Protamine Administration after Cardiopulmonary Bypass on Complement, Blood Elements, and the Hemodynamic State

1986 • 247 citations

Association of Protamine IgE and IgG Antibodies with Life-Threatening Reactions to Intravenous Protamine

1989 • 202 citations

Complement activation by interaction of polyanions and polycations. I. Heparin-protamine induced consumption of complement.

1975 • 201 citations

Catastrophic Pulmonary Vasoconstriction Associated with Protamine Reversal of Heparin

1983 • 166 citations

Modulation of the formation of the amplification convertase of complement, C3b, Bb, by native and commercial heparin.

1978 • 165 citations

C5a and Thromboxane Generation Associated with Pulmonary Vaso- and Broncho-constriction during Protamine Reversal of Heparin

1987 • 163 citations

Increased risk of severe protamine reactions in NPH insulin-dependent diabetics undergoing cardiac catheterization.

1984 • 154 citations

Complement Activation by Interaction of Polyanions and Polycations

1975 • 151 citations

Radioimmunoassay for anaphylatoxins: A sensitive method for determining complement activation products in biological fluids

1984 • 142 citations

Evidence for complement activation by protamine-heparin interaction after cardiopulmonary bypass.

1985 • 136 citations

Granulocyte Collection by Continuous-flow Filtration Leukapheresis

1972 • 134 citations

Complement Activation by Interaction of Polyanions and Polycations

1977 • 120 citations

Mode of interaction of different polyanions with the first () the second (C2) and the fourth (C4) component of complement—I

1976 • 117 citations

Anaphylaxis to protamine sulfate mediated by a complement-dependent IgG antibody

1978 • 86 citations

Noncardiogenic Pulmonary Edema and Peripheral Vascular Collapse Following Cardiopulmonary Bypass: Rare Protamine Reaction?

1980 • 86 citations

An Anaphylactic Reaction to Protamine in a Patient Allergic to Fish

1981 • 82 citations

Mode of interaction of different polyanions with the first (), the second (C2) and the fourth (C4) component of complement—II

1976 • 78 citations

Protamine-induced fatal anaphylaxis

1985 • 75 citations

Serious adverse reactions to protamine sulfate: Are alternatives needed?

1985 • 72 citations

Increased risk of severe protamine reactions in NPH insulin-dependent diabetics undergoing cardiac catheterization.

1984 • 65 citations

Complement Activation in Cardiopulmonary Bypass, with Special Reference to Anaphylatoxin Production in Membrane and Bubble Oxygenators

1988 • 64 citations

Protamine-induced fatal anaphylaxis. Prevalence of antiprotamine immunoglobulin E antibody.

1985 • 64 citations

Severe Circulatory Shock following Protamine (An Anaphylactic Reaction)

1980 • 61 citations

Reactive Hypoglycemia: Fact or Fiction?

1976 • 61 citations

Adverse reactions to protamine sulfate following cardiac surgery

1984 • 58 citations

COMPLEMENT ACTIVATION DURING CARDIOPULMONARY BYPASS BY HEPARIN-PROTAMINE INTERACTION

1984 • 57 citations

Protamine Sulfate and Fish Allergy

1976 • 42 citations

In vivo complement activation by polyanion-polycation complexes: Evidence that C5a is generated intravascularly during heparin-protamine interaction

1983 • 39 citations

Shock due to protamine hypersensitivity

1982 • 38 citations

Anaphylactic shock following protamine administration.

1982 • 34 citations

Complement Activation in Extracorporeal Circulation: Physiological and Pathological Implications

1986 • 33 citations

Cardiac arrest following protamine administration

1984 • 30 citations

Allergic reaction to protamine: A late complication of elective vasectomy?

1983 • 27 citations

Sustained Hypotension Secondary To Protamine Sulfate

1970 • 23 citations

Polyions regulate the alternative amplification pathway of complement

1983 • 15 citations

Hypertension associated with protamine sulfate administration

1981 • 10 citations

Cardiopulmonary Bypass-induced Complement Activation. Evidence for C5a Participation

1982 • 8 citations