Activation of histamine H2 receptors ameliorates experimental allergic encephalomyelitis

Anti—tumor necrosis factor therapy abrogates autoimmune demyelination

1991 • 434 citations

Experimental Autoimmune Encephalomyelitis Is Exacerbated in Mice Lacking theNOS2Gene

1998 • 226 citations

Lymphotoxin

1988 • 205 citations

Histamine suppresses gene expression and synthesis of tumor necrosis factor alpha via histamine H2 receptors.

1991 • 165 citations

Elevated secretion of reactive nitrogen and oxygen intermediates by inflammatory leukocytes in hyperacute experimental autoimmune encephalomyelitis: enhancement by the soluble products of encephalitogenic T cells.

1992 • 136 citations

Nitric oxide and T helper cell immunity

2001 • 134 citations

Inhibition of autoimmune neuropathological process by treatment with an iron-chelating agent.

1984 • 120 citations

Astrocyte-Targeted Expression of IL-12 Induces Active Cellular Immune Responses in the Central Nervous System and Modulates Experimental Allergic Encephalomyelitis

2000 • 96 citations

Hydroxyzine inhibits experimental allergic encephalomyelitis (EAE) and associated brain mast cell activation

2000 • 93 citations

Superoxide Prevents Nitric Oxide-Mediated Suppression of Helper T Lymphocytes: Decreased Autoimmune Encephalomyelitis in Nicotinamide Adenine Dinucleotide Phosphate Oxidase Knockout Mice

2000 • 93 citations

Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat.

1997 • 93 citations

In vitro study of mediators of inflammation in multiple sclerosis

1989 • 91 citations

Chemical Analysis of Multiple Sclerosis Lesions by FT-IR Microspectroscopy

1998 • 76 citations

Anti-IL-12 antibody prevents the development and progression of multiple sclerosis-like relapsing–remitting demyelinating disease in NOD mice induced with myelin oligodendrocyte glycoprotein peptide

2000 • 66 citations

Histamine inhibits chemotaxis, phagocytosis, superoxide anion production, and the production of TNFα and IL-12 by macrophages via H2-receptors

2001 • 57 citations

A double-blind pilot study of the effect of Prokarin™ on fatigue in multiple sclerosis

2002 • 46 citations

Characterization of histamine H2-receptors in human neutrophils with a series of guanidine analogues of impromidine

1990 • 35 citations

Hydrogen Peroxide Localization in Experimental Optic Neuritis

1990 • 33 citations

Evidence of free radical damage in the central nervous system of guinea-pigs at the prolonged acute and early relapse stages of chronic relapsing experimental allergic encephalomyelitis

1993 • 31 citations

Tumor necrosis factor alpha but not lymphotoxin is overproduced by blood mononuclear cells in multiple sclerosis.

1995 • 25 citations

TNF-receptor 1 deficiency fails to alter the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice) but affords protection following LPS challenge

2000 • 19 citations

Effect of H1 and H2 agonists on the chemiluminescence of human blood mononuclear cells induced by phytohaemagglutinin

1985 • 9 citations

Effect of histamine on delayed-type hypersensitivity in mice

1986 • 9 citations

Regulation of Antibody-Dependent Cellular Cytotoxicity in Multiple Sclerosis by Central Nervous System Hormones

1987 • 7 citations