Hepcidin and anaemia

Anemia of Chronic Disease

2005 • 3,522 citations

Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver

2001 • 2,140 citations

Anemia and Blood Transfusion in Critically Ill Patients

2002 • 1,756 citations

A New Mouse Liver-specific Gene, Encoding a Protein Homologous to Human Antimicrobial Peptide Hepcidin, Is Overexpressed during Iron Overload

2001 • 1,673 citations

Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation

2003 • 1,516 citations

The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation

2002 • 1,414 citations

Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein

2003 • 1,392 citations

LEAP‐1, a novel highly disulfide‐bonded human peptide, exhibits antimicrobial activity

2000 • 1,313 citations

Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 ( USF2 ) knockout mice

2001 • 1,212 citations

Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis

2002 • 872 citations

Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease

2002 • 638 citations

Progress in understanding the pathogenesis of the anemia of chronic disease [see comments]

1992 • 612 citations

Nutritional deficiencies and blunted erythropoietin response as causes of the Amemia of critical illness

2001 • 280 citations

Hepcidin: A putative iron-regulatory hormone relevant to hereditary hemochromatosis and the anemia of chronic disease

2001 • 271 citations

Expression of hepcidin in hereditary hemochromatosis: evidence for a regulation in response to the serum transferrin saturation and to non-transferrin-bound iron

2003 • 246 citations

Cachectin/tumor necrosis factor‐α alters red blood cell kinetics and induces anemia in vivo

1989 • 230 citations

Advances in the anemia of chronic disease.

1999 • 198 citations

Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor.

1989 • 195 citations

Pathogenesis of the anemia of chronic disease: A cytokine‐mediated anemia

1995 • 194 citations

Recent developments in the anemia of chronic disease.

2003 • 192 citations

Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13.

1997 • 181 citations

Role of IL-10 for Induction of Anemia During Inflammation

2002 • 172 citations

Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.

1986 • 155 citations

Iron metabolism and erythropoiesis after surgery

1998 • 148 citations

Inhibition of human erythroid colony‐forming units by interleukin‐1 is mediated by gamma interferon

1992 • 147 citations

Inhibition of human erythroid colony-forming units by tumor necrosis factor requires beta interferon.

1993 • 145 citations

The anemia of chronic disease: Spectrum of associated diseases in a series of unselected hospitalized patients

1989 • 144 citations

Serum immunoreactive erythropoietin in rheumatoid arthritis: impaired response to anemia

1988 • 139 citations

Nitric Oxide–Mediated Induction of Ferritin Synthesis in J774 Macrophages by Inflammatory Cytokines: Role of Selective Iron Regulatory Protein-2 Downregulation

1998 • 137 citations

Serum hepcidin in clinical specimens

2003 • 117 citations

The pathogenesis of anemia in rheumatoid arthritis: A clinical and laboratory analysis

1990 • 113 citations

Anemia of chronic disorders in systemic autoimmune diseases.

1997 • 96 citations

Measurements of serum ferritin used to predict concentrations of iron in bone marrow in anemia of chronic disease

1991 • 80 citations

Serum soluble transferrin receptor and the prediction of marrow aspirate iron results in a heterogeneous group of patients

1999 • 77 citations

Correlation between neopterin, interferon‐gamma and haemoglobin in patients with haematological disorders

1990 • 77 citations

Some Observations on Anemia in Rheumatoid Arthritis

1953 • 68 citations

Prediction of iron deficiency in chronic inflammatory rheumatic disease anaemia

1995 • 67 citations

Effect of nitric oxide on expression of transferrin receptor and ferritin and on cellular iron metabolism in K562 human erythroleukemia cells

1995 • 65 citations

The Role of Cytokines in the Regulation of Ferritin Expression

1994 • 58 citations

Inhibition of erythroid colony formation by autologous bone marrow adherent cells from patients with the anemia of chronic disease

1983 • 47 citations

The Role of Nitric Oxide in the Regulation of Cellular Iron Metabolism

1997 • 40 citations

Serum transferrin receptor levels in patients undergoing evaluation of iron stores: correlation with other parameters and observed versus predicted results

1997 • 39 citations

Normal Response to Erythropoietin or Hypoxia in Rats Made Anemic with Turpentine Abscess.

1963 • 31 citations

Examination of the mechanism of action of nitrogen monoxide on iron uptake from transferrin

2000 • 16 citations

Unlocking the mysteries of iron homeostasis and of the anemia of chronic disease: is hepcidin the key?

2003 • 8 citations

Action of blood serum from rats with turpentine sterile inflammation on the development of CFU erythrocyte colonies. Possible role of erythropoietin.

1989 • 1 citations