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Progress in understanding the pathogenesis of the anemia of chronic disease [see comments]

Data up to Jan 2025

Published1992
Citations612
References75

Total Citations Per Year

Abstract

References (75)

Anemia of Chronic Disease

2005 • 3,522 citations

Correction of the Anemia of End-Stage Renal Disease with Recombinant Human Erythropoietin

1987 • 2,006 citations

Immune Interferon in the Circulation of Patients with Autoimmune Disease

1979 • 907 citations

Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1

1986 • 781 citations

Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome

1988 • 739 citations

Neopterin as a marker for activated cell-mediated immunity: Application in HIV infection

1988 • 573 citations

The suppressive influences of human tumor necrosis factors on bone marrow hematopoietic progenitor cells from normal donors and patients with leukemia: synergism of tumor necrosis factor and interferon-gamma.

1986 • 492 citations

CORRELATION OF PLASMA INTERLEUKIN 1 LEVELS WITH DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS

1988 • 490 citations

Erythropoietin Treatment of Anemia Associated with Multiple Myeloma

1990 • 459 citations

Elevated tumor necrosis factor alpha and interleukin-6 serum levels as markers for complicated plasmodium falciparum malaria

1989 • 438 citations

Phase I study of recombinant tumor necrosis factor in cancer patients.

1987 • 430 citations

Interferon-Gamma, the Activated Macrophage, and Host Defense Against Microbial Challenge

1988 • 428 citations

EVIDENCE FOR TUMOUR NECROSIS FACTOR/CACHECTIN PRODUCTION IN CANCER

1987 • 425 citations

Anemia of Chronic Disorders

1984 • 419 citations

Serum transferrin receptor distinguishes the anemia of chronic disease from iron deficiency anemia.

1992 • 383 citations

Comparative analysis of the influences of human gamma, alpha and beta interferons on human multipotential (CFU-GEMM), erythroid (BFU-E) and granulocyte-macrophage (CFU-GM) progenitor cells.

1983 • 373 citations

Neopterin as Marker for Activation of Cellular Immunity: Immunologic Basis and Clinical Application

1989 • 373 citations

Circulating Activated Suppressor T Lymphocytes in Aplastic Anemia

1985 • 349 citations

Recombinant Human Erythropoietin for Patients with AIDS Treated with Zidovudine

1990 • 347 citations

In vivo effects of recombinant human interleukin-6 in primates: stimulated production of platelets

1990 • 280 citations

Interleukin 1 stimulates fibroblasts to synthesize granulocyte-macrophage and granulocyte colony-stimulating factors. Mechanism for the hematopoietic response to inflammation.

1988 • 247 citations

Multicenter study of recombinant human erythropoietin in correction of anemia in rheumatoid arthritis

1990 • 237 citations

Cachectin/tumor necrosis factor‐α alters red blood cell kinetics and induces anemia in vivo

1989 • 230 citations

Purification of human erythroid colony-forming units and demonstration of specific binding of erythropoietin.

1987 • 225 citations

Blunted erythropoietin response to anaemia in rheumatoid arthritis

1987 • 221 citations

Monokines inhibiting erythropoietin production in human hepatoma cultures and in isolated perfused rat kidneys

1992 • 209 citations

Studies of interferon as a regulator of hematopoietic cell proliferation.

1985 • 195 citations

Induction of hypoferremia and modulation of macrophage iron metabolism by tumor necrosis factor.

1989 • 195 citations

Interferon is the suppressor of hematopoiesis generated by stimulated lymphocytes in vitro.

1984 • 180 citations

Erythropoietin for the treatment of anemia of malignancy associated with neoplastic bone marrow infiltration.

1990 • 162 citations

Inhibition of human erythroid colony-forming units by gamma interferon can be corrected by recombinant human erythropoietin [see comments]

1991 • 158 citations

Tumor necrosis factor-alpha and hematopoietic progenitors: effects of tumor necrosis factor on the growth of erythroid progenitors CFU-E and BFU-E and the hematopoietic cell lines K562, HL60, and HEL cells.

1987 • 155 citations

Inhibition of human erythroid colony‐forming units by interleukin‐1 is mediated by gamma interferon

1992 • 147 citations

Inhibition of human erythroid colony-forming units by tumor necrosis factor requires beta interferon.

1993 • 145 citations

The anemia of chronic disease: Spectrum of associated diseases in a series of unselected hospitalized patients

1989 • 144 citations

In vivo hematopoietic effects of recombinant interleukin-1 alpha in mice: stimulation of granulocytic, monocytic, megakaryocytic, and early erythroid progenitors, suppression of late-stage erythropoiesis, and reversal of erythroid suppression with erythropoietin

1989 • 141 citations

Immune activation and the anaemia associated with chronic inflammatory disorders

1991 • 141 citations

Inhibition by interleukin-1 of the action of erythropoietin on erythroid precursors and its possible role in the pathogenesis of hypoplastic anaemias

1987 • 140 citations

Serum immunoreactive erythropoietin in rheumatoid arthritis: impaired response to anemia

1988 • 139 citations

Suppression of normal human erythropoiesis by gamma interferon in vitro. Role of monocytes and T lymphocytes.

1985 • 139 citations

Radioimmunoassay of tumor necrosis factor in serum.

1987 • 138 citations

Plasma erythropoietin in health and disease.

1980 • 135 citations

Quantitation of specific binding of erythropoietin to human erythroid colony‐forming cells

1988 • 129 citations

Treatment of the anemia of rheumatoid arthritis with recombinant human erythropoietin: Clinical and in vitro studies

1989 • 126 citations

Phase I trial of recombinant interferon gamma in cancer patients.

1986 • 121 citations

The pathogenesis of anemia in rheumatoid arthritis: A clinical and laboratory analysis

1990 • 113 citations

In vivo suppression of erythropoiesis by tumor necrosis factor-alpha (TNF-alpha): reversal with exogenous erythropoietin (EPO).

1990 • 111 citations

Tumor necrosis factor: immunologic, antitumor, metabolic, and cardiovascular activities.

1990 • 104 citations

Inhibition of human colony-forming-unit erythroid by tumor necrosis factor requires accessory cells.

1990 • 81 citations

Effects of type β transforming growth factors on haematopoietic progenitor cells

1988 • 70 citations

Effects of recombinant human tumor necrosis factor alpha, recombinant human gamma-interferon, and prostaglandin E on colony formation of human hematopoietic progenitor cells stimulated by natural human pluripotent colony-stimulating factor, pluripoietin alpha, and recombinant erythropoietin in serum-free cultures.

1986 • 69 citations

Serum erythropoietin in rheumatoid arthritis and other inflammatory arthritides: relationship to anaemia and the effect of anti‐inflammatory treatment

1987 • 68 citations

DEFECTIVE REUTILIZATION OF IRON IN THE ANEMIA OF INFLAMMATION.

1965 • 62 citations

In vitro suppression of erythropoiesis by bone marrow adherent cells from some patients with fungal infection

1982 • 59 citations

The Anaemia of Chronic Disorders

1983 • 55 citations

Effects of recombinant human tumor necrosis factor (rhtnf) on normal human and mouse hemopoietic progenitor cells

1987 • 48 citations

In vivo hematopoietic effects of tumor necrosis factor-alpha in normal and erythroleukemic mice: characterization and therapeutic applications

1988 • 48 citations

Anaemia of chronic disease in rheumatoid arthritis

1990 • 45 citations

The Anaemia of Chronic Disorders: Studies of Iron Reutilization in the Anaemia of Experimental Malignancy and Chronic Inflammation

1977 • 41 citations

Transforming Growth Factor‐β in Rheumatoid Arthritis

1990 • 39 citations

Erythropoietin fails to reverse the anemia in mice continuously exposed to tumor necrosis factor-alpha in vivo.

1990 • 33 citations

Normal Response to Erythropoietin or Hypoxia in Rats Made Anemic with Turpentine Abscess.

1963 • 31 citations

The mechanism of the anaemia in rheumatoid arthritis: effects of bone marrow adherent cells and of serum on in‐vitro erythropoiesis

1984 • 29 citations

Lymphocytes and lymphokines in aplastic anemia: pathogenic role and implications for pathogenesis.

1987 • 26 citations

Anaemia in Rheumatoid Arthritis: Role of Cytokines

1989 • 25 citations

Erythropoietin in Patients with Anaemia in Rheumatoid Arthritis

1979 • 21 citations

Role of the reticuloendothelial system in the anaemia of rheumatoid arthritis. A study using the 59Fe-labelled dextran model.

1974 • 21 citations

Anemia of Chronic Inflammatory Arthritides: Treatment with Recombinant Human Erythropoietin

2015 • 18 citations

Two Forms of Transforming Growth Factor‐β Are Equally Potent Selective Growth Inhibitors of Early Murine Hematopoiesisab

1990 • 18 citations

Different haematopoietic growth factors have different capacity in overcoming the in vitro interferon gamma-induced suppression of bone marrow progenitor cells

1990 • 16 citations

Immunological aspects of the anemia of rheumatoid arthritis

1987 • 14 citations

In-vitro studies of ineffective erythropoiesis in rheumatoid arthritis

1982 • 14 citations

Interferon production by human marrow stromal cells

1983 • 13 citations

Effects of erythropoietin injection on the anemic rats with different serum erythropoietin titer.

1987 • 7 citations

Recombinant Human Erythropoietin, but Not Iron Supplementation, Improved Anemia in Rats with Adjuvant-Induced Arthritis.

1991 • 4 citations

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Progress in understanding the pathogenesis of the anemia of chronic disease [see comments] (1992) – Blood | Metascience Observatory Explorer