The Retinoid X Receptor Agonist 9-cis-Retinoic Acid and the 24-Hydroxylase Inhibitor Ketoconazole Increase Activity of 1,25-Dihydroxyvitamin D3 in Human Skin In Vivo

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

A transcriptional co-repressor that interacts with nuclear hormone receptors

1995 • 1,744 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids.

1993 • 738 citations

1,25-DIHYDROXYVITAMIN D₃AND MALIGNANT MELANOMA: THE PRESENCE OF RECEPTORS AND INHIBITION OF CELL GROWTH IN CULTURE

1981 • 560 citations

Two nuclear signalling pathways for vitamin D

1993 • 559 citations

Effect of 1α,25-Dihydroxyvitamin D3 on the Morphologic and Biochemical Differentiation of Cultured Human Epidermal Keratinocytes Grown in Serum-Free Conditions

1986 • 460 citations

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1989 • 409 citations

1α,25-Dihydroxycholecalciferol and a human myeloid leukaemia cell line (HL-60)

1982 • 398 citations

Application of Retinol to Human Skin In Vivo Induces Epidermal Hyperplasia and Cellular Retinoid Binding Proteins Characteristic of Retinoic Acid but Without Measurable Retinoic Acid Levels or Irritation

1995 • 328 citations

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.

1993 • 272 citations

The Response of Intestinal Calcium Transport to 25-Hydroxy and 1,25-Dihydroxy Vitamin D in Nephrectomized Rats

1972 • 241 citations

Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene.

1994 • 231 citations

1,24,25-Trihydroxyvitamin D3

1973 • 224 citations

Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP). Retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro.

1991 • 200 citations

Immunocytochemical Detection of 1,25-Dihydroxyvitamin D Receptors in Normal Human Tissues*

1988 • 196 citations

Identification of a 1,25-dihydroxyvitamin D3-response element in the 5'-flanking region of the rat calbindin D-9k gene.

1992 • 191 citations

Two Vitamin D Response Elements Function in the Rat 1,25-Dihydroxyvitamin D 24-Hydroxylase Promoter

1995 • 190 citations

Immunological identification and functional quantitation of retinoic acid and retinoid X receptor proteins in human skin.

1994 • 179 citations

1,25-Dihydroxycholecalciferol: Metabolite of Vitamin D ₃ Active on Bone in Anephric Rats

1972 • 171 citations

Expression of 1,25-Dihydroxyvitamin D3 Receptors in Normal and Psoriatic Skin

1991 • 160 citations

Human skin levels of retinoic acid and cytochrome P-450-derived 4-hydroxyretinoic acid after topical application of retinoic acid in vivo compared to concentrations required to stimulate retinoic acid receptor-mediated transcription in vitro.

1992 • 126 citations

Isolation and characterization of a cytochrome P-450 from rat kidney mitochondria that catalyzes the 24-hydroxylation of 25-hydroxyvitamin D3

1991 • 107 citations

RESPONSE OF SCALP PSORIASIS TO ORAL KETOCONAZOLE

1985 • 94 citations

Treatment of seborrhoeic dermatitis with ketoconazole: II. Response of seborrhoeic dermatitis of the face, scalp and trunk to topical ketoconazole

1987 • 93 citations

Antiproliferative responses to two human colon cancer cell lines to vitamin D3 are differently modified by 9-cis-retinoic acid.

1996 • 87 citations

Current therapy of dermatophytosis

1994 • 83 citations

Ketoconazole and liarozole in the treatment of advanced prostatic cancer

1993 • 82 citations

Selective Effects of Ligands on Vitamin D₃ Receptor- and Retinoid X Receptor-Mediated Gene Activation In Vivo

1996 • 79 citations

Inhibition of Human T Lymphocyte Proliferation and Cytokine Production by 1,25-Dihydroxyvitamin D₃. Differential Effects on Cd45Ra+ and Cd45R0+ Cells

1993 • 73 citations

Protooncogene Expression in Normal and Psoriatic Skin

1990 • 73 citations

Retinoic Acid Isomers Applied to Human Skin in Vivo Each Induce a 4-Hydroxylase That Inactivates Only Trans Retinoic Acid

1996 • 58 citations

Immunosuppressive effects of 1,2 5-dihydroxyvitamin D3 and its analogue calcipotriol on epidermal cells

1994 • 57 citations

Comparison of CD271 (Adapalene) and All-Trans Retinoic Acid in Human Skin: Dissociation of Epidermal Effects and CRABP-II mRNA Expression

1993 • 52 citations

Transcriptional Activity of a Fluorinated Vitamin D Analog on VDR-RXR-Mediated Gene Expression

1995 • 51 citations

Retinoid X Receptor Acts as a Hormone Receptor in Vivo to Induce a Key Metabolic Enzyme for 1,25-Dihydroxyvitamin D3

1995 • 50 citations

Liarozole Inhibits Human Epidermal Retinoic Acid 4-Hydroxylase Activity and Differentially Augments Human Skin Responses to Retinoic Acid and Retinol In Vivo

1996 • 38 citations

Retinoid X receptor isotype identity directs human vitamin D receptor heterodimer transactivation from the 24-hydroxylase vitamin D response elements in yeast.

1996 • 38 citations

Expression of 25-Hydroxyvitamin D3-24-Hydroxylase mRNA in Cultured Human Keratinocytes

1994 • 37 citations

Retinoid X Receptor-Specific Ligands Synergistically Upregulate 1, 25-Dihydroxyvitamin D3-Dependent Transcription in Epidermal Keratinocytes In Vitro and In Vivo

1997 • 35 citations

Vitamin D3 and skin diseases

1992 • 34 citations

Retinoid Induction of CRABP II mRNA in Human Dermal Fibroblasts: Use as a Retinoid Bioassay

1996 • 24 citations