Retinoid X receptor isotype identity directs human vitamin D receptor heterodimer transactivation from the 24-hydroxylase vitamin D response elements in yeast.

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

1995 • 2,059 citations

Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

1991 • 1,725 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

RXRβ: A coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements

1991 • 1,241 citations

The Role of the Vitamin D Endocrine System in Health and Disease

1989 • 1,041 citations

Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors

1992 • 966 citations

Cloning and expression of full-length cDNA encoding human vitamin D receptor.

1988 • 961 citations

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1995 • 629 citations

Polarity-specific activities of retinoic acid receptors determined by a co-repressor

1995 • 569 citations

DMSO-enhanced whole cell yeast transformation

1991 • 534 citations

The vitamin D story: a collaborative effort of basic science and clinical medicine ¹

1988 • 531 citations

Identification of a DNA sequence responsible for binding of the 1,25-dihydroxyvitamin D3 receptor and 1,25-dihydroxyvitamin D3 enhancement of mouse secreted phosphoprotein 1 (SPP-1 or osteopontin) gene expression.

1990 • 467 citations

1,25-Dihydroxyvitamin D-Responsive Element and Glucocorticoid Repression in the Osteocalcin Gene

1989 • 418 citations

Sequence elements in the human osteocalcin gene confer basal activation and inducible response to hormonal vitamin D3.

1989 • 409 citations

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

1990 • 313 citations

RARs and RXRs: evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo.

1993 • 305 citations

Retinoid X receptors stimulate and 9-cis retinoic acid inhibits 1,25-dihydroxyvitamin D3-activated expression of the rat osteocalcin gene.

1993 • 272 citations

Identification of a vitamin D-responsive element in the 5'-flanking region of the rat 25-hydroxyvitamin D3 24-hydroxylase gene.

1994 • 231 citations

The Vitamin D Receptor Interacts with General Transcription Factor IIB

1995 • 166 citations

Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast.

1992 • 116 citations

Genetic dissection of the signaling domain of a mammalian steroid receptor in yeast.

1992 • 105 citations

Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae.

1989 • 101 citations

Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells.

1994 • 92 citations

Response element selectivity for heterodimerization of vitamin D receptors with retinoic acid and retinoid X receptors

1994 • 64 citations

Highly potent transcriptional activation by 16-ene derivatives of 1,25-dihydroxyvitamin D3. Lack of modulation by 9-cis-retinoic acid of response to 1,25-dihydroxyvitamin D3 or its derivatives.

1994 • 61 citations

Homo- and heterodimers of the retinoid X receptor (RXR) activate transcription in yeast

1994 • 55 citations

The mouse Rxrb gene encoding RXRβ: genomic organization and two mRNA isoforms generated by alternative splicing of transcripts initiated from CpG island promoters

1994 • 45 citations

Isolation of a full-length cDNA clone encoding a N-terminally variant form of the human retinoid X receptor β

1992 • 43 citations