Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol.

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

An Efficient mRNA‐Dependent Translation System from Reticulocyte Lysates

1976 • 3,994 citations

The scanning model for translation: an update.

1989 • 3,525 citations

Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma.

1975 • 3,026 citations

The epitopes of influenza nucleoprotein recognized by cytotoxic T lymphocytes can be defined with short synthetic peptides

1986 • 1,723 citations

Antigen Recognition by Class I-Restricted T Lymphocytes

1989 • 1,207 citations

Introduction of soluble protein into the class I pathway of antigen processing and presentation

1988 • 1,105 citations

Transfer of Proteins Across Membranes

1981 • 894 citations

The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology

1986 • 861 citations

One molecule of diphtheria toxin fragment a introduced into a cell can kill the cell

1978 • 744 citations

Multiple Mechanisms of Protein Insertion into and Across Membranes

1985 • 720 citations

Cytotoxic T cells recognize fragments of the influenza nucleoprotein

1985 • 669 citations

Diphtheria Toxin-dependent Adenosine Diphosphate Ribosylation of Aminoacyl Transferase II and Inhibition of Protein Synthesis

1968 • 536 citations

Transcending the impenetrable: How proteins come to terms with membranes

1988 • 471 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

Cytotoxic T lymphocytes recognize a fragment of influenza virus matrix protein in association with HLA-A2

1987 • 429 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.

1983 • 307 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.

1990 • 267 citations

How do polypeptides cross the mitochondrial membranes?

1990 • 246 citations

The binary logic of antigen processing and presentation to T cells

1990 • 235 citations

Structure and Activity of Diphtheria Toxin

1971 • 229 citations

Fine-tuning the topology of a polytopic membrane protein: Role of positively and negatively charged amino acids

1990 • 221 citations

The role of charged amino acids in the localization of secreted and membrane proteins

1990 • 219 citations

Cells Process Exogenous Proteins for Recognition by Cytotoxic T Lymphocytes

1988 • 217 citations

Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration

1985 • 188 citations

Reconstitution of Diphtheria Toxin from Two Nontoxic Cross-Reacting Mutant Proteins

1972 • 177 citations

Alteration of the amino terminus of the mature sequence of a periplasmic protein can severely affect protein export in Escherichia coli.

1988 • 163 citations

Transport and routing of proteins into chloroplasts

1989 • 155 citations

Cloning and structural characterization of a human non-erythroid band 3-like protein.

1986 • 155 citations

Signals guiding proteins to their correct locations in mitochondria

1987 • 145 citations

Secondary Structure of Diphtheria Toxin and Its Fragments Interacting with acidic Liposomes Studied by Polarized Infrared Spectroscopy

1989 • 134 citations

Low pH-induced release of diphtheria toxin A-fragment in Vero cells. Biochemical evidence for transfer to the cytosol.

1988 • 85 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Insertion of diphtheria toxin B-fragment into the plasma membrane at low pH. Characterization and topology of inserted regions

1991 • 78 citations

Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH.

1987 • 75 citations

Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments.

1984 • 71 citations

The pH-dependent conformational change of diphtheria toxin.

1988 • 58 citations

Diphtheria toxin entry: protein translocation in the reverse direction

1988 • 57 citations

Expression of a mutant, full-length form of diphtheria toxin in Escherichia coli

1987 • 50 citations

Entry of Polypeptide Toxins into Animal Cells

1985 • 47 citations

Conformation and model membrane interactions of diphtheria toxin fragment A.

1988 • 46 citations

Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane.

1988 • 45 citations

Membrane interactions of diphtheria toxin analyzed using in vitro synthesized mutants.

1989 • 41 citations

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