Conformation and model membrane interactions of diphtheria toxin fragment A.

Solubilization of membranes by detergents

1975 • 2,909 citations

Fluorescence quenching studies with proteins

1981 • 1,700 citations

Exposure of tryptophanyl residues in proteins. Quantitative determination by fluorescence quenching studies

1976 • 1,020 citations

Diphtheria Toxin

1977 • 780 citations

Membrane fusion proteins of enveloped animal viruses

1983 • 670 citations

Proteinase K from Tritirachium album Limber

1974 • 607 citations

Diphtheria toxin: mode of action and structure

1975 • 552 citations

Diphtheria toxin entry into cells is facilitated by low pH.

1980 • 467 citations

CRYSTALLINE PAPAIN

1954 • 456 citations

The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement.

1980 • 372 citations

Diphtheria toxin fragment forms large pores in phospholipid bilayer membranes.

1981 • 341 citations

Channels formed by botulinum, tetanus, and diphtheria toxins in planar lipid bilayers: relevance to translocation of proteins across membranes.

1985 • 309 citations

Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.

1983 • 307 citations

Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule.

1981 • 291 citations

Diphtheria toxin forms transmembrane channels in planar lipid bilayers.

1981 • 281 citations

Lipid selectivity of the calcium and magnesium ion dependent adenosine triphosphatase, studied with fluorescence quenching by a brominated phospholipid

1982 • 265 citations

Fluorescence quenching of model membranes. 3. Relationship between calcium adenosinetriphosphatase enzyme activity and the affinity of the protein for phosphatidylcholines with different acyl chain characteristics

1981 • 232 citations

Effect of pH on the conformation of diphtheria toxin and its implications for membrane penetration

1985 • 188 citations

Mutations in Diphtheria Toxin Separate Binding from Entry and Amplify Immunotoxin Selectivity

1987 • 173 citations

Observations on the Structure of Diphtheria Toxin

1971 • 169 citations

Interaction of Fragment A from Diphtheria Toxin with Nicotinamide Adenine Dinucleotide

1974 • 147 citations

Binding of triton X-100 to diphtheria toxin, crossreacting material 45, and their fragments.

1976 • 139 citations

Tetanus toxin fragment forms channels in lipid vesicles at low pH.

1982 • 138 citations

Adp-Ribosylation Reactions: Biology and Medicine

1982 • 132 citations

Nucleotide Sequence and Expression of the Diphtheria tox 228 Gene in Escherichia coli

1983 • 120 citations

The complete nucleotide sequence of the gene coding for diphtheria toxin in the corynephage omega (tox⁺) genome

1983 • 110 citations

pH-dependence of the phospholipid interaction of diphtheria-toxin fragments

1985 • 89 citations

Evidence for direct insertion of fragments A and B of diphtheria toxin into model membranes.

1984 • 87 citations

Corrections for inner-filter effects in fluorescence quenching measurements via right-angle and front-surface illumination

1978 • 85 citations

Determination of the topography of cytochrome b5 in lipid vesicles by fluorescence quenching

1985 • 83 citations

Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane

1984 • 80 citations

Primary structure of diphtheria toxin fragment B: structural similarities with lipid-binding domains.

1980 • 77 citations

Mechanism of insertion of diphtheria toxin: peptide entry and pore size determinations.

1984 • 77 citations

Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH.

1986 • 71 citations

Protein Engineering: Applications In Science, Medicine, and Industry

1986 • 68 citations

Acidic pH requirement for insertion of colicin E1 into artificial membrane vesicles: relevance to the mechanism of action of colicins and certain toxins.

1985 • 58 citations

Mechanism of exchange of cytochrome b5 between phosphatidylcholine vesicles

1980 • 53 citations

Amino-acid sequence of fragment A, an enzymically active fragment from diphtheria toxin.

1976 • 52 citations

Similarity of the conformation of diphtheria toxin at high temperature to that in the membrane-penetrating low-pH state.

1986 • 51 citations

Requirements for the translocation of diphtheria toxin fragment A across lipid membranes.

1985 • 50 citations

Localization in diphtheria toxin fragment B of a region that induces pore formation in planar lipid bilayers at low pH

1983 • 48 citations

Diphtheria toxin induces fusion of small unilamellar vesicles at low pH

1984 • 45 citations

Fluorescence characterization of the low pH-induced change in diphtheria toxin conformation: Effect of salt

1984 • 41 citations

Quantal entry of diphtheria toxin to the cytosol.

1985 • 37 citations

A fluorescence-based detergent binding assay for protein hydrophobicity

1986 • 36 citations

Interaction of Diphtheria Toxin Fragments A, B and Protein crm 45 with Liposomes

1979 • 35 citations

Occurrence of tryptophan in the enzymically active site of diphtheria toxin fragment a

1977 • 34 citations

Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport.

1986 • 33 citations

The Harvey Lectures. Series 51. (1955-56)

1957 • 31 citations

Interaction of diphtheria toxin with model membranes

1988 • 30 citations

Localization of the active site of diphtheria toxin

1988 • 30 citations

Immunotoxins

1984 • 30 citations

Interactions of diphtheria toxin with lipid vesicles: determinants of ion channel formation

1987 • 29 citations

Pseudomonas exotoxin A. Membrane binding, insertion, and traversal.

1986 • 27 citations

The complete amino acid sequence of diphtheria toxin fragment B. Correlation with its lipid-binding properties

1985 • 27 citations

Single mutation in the A domain of diphtheria toxin results in a protein with altered membrane insertion behavior

1987 • 26 citations

A CNBR peptide located in the middle region of diphtheria toxin fragment B induces conductance change in lipid bilayers

1981 • 25 citations

Diphtheria Toxin Fragment Channels in Lipid Bilayer Membranes

1984 • 25 citations

The Diphtheria Toxin Structural Gene

1985 • 20 citations

Circular dichroism of diphtheria toxin, Pseudomonas aeruginosa exotoxin A, and various derivatives

1985 • 18 citations

Aggregation and fusion of lipid vesicles induced by diphtheria toxin at low pH: Possible involvement of the P site and the NAD+ binding site

1985 • 14 citations

Mutant with diphtheria toxin receptor and acidification function but defective in entry of toxin

1987 • 8 citations

Thermal stability of different forms of diphtheria toxin

1984 • 6 citations

Reply from ward

1987 • 4 citations