The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology

Three-dimensional model of purple membrane obtained by electron microscopy

1975 • 2,259 citations

Intracellular protein topogenesis

1980 • 1,378 citations

TnphoA: a transposon probe for protein export signals.

1985 • 1,030 citations

The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis

1981 • 868 citations

Sequence of the lactose permease gene

1980 • 501 citations

Nucleotide sequence of the filamentous bacteriophage M13 DNA genome: comparison with phage fd

1980 • 405 citations

The membrane dipole potential in a total membrane potential model. Applications to hydrophobic ion interactions with membranes

1986 • 362 citations

Hypothesis about the function of membrane-buried proline residues in transport proteins.

1986 • 334 citations

Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium

1982 • 322 citations

Sequence of the leader peptidase gene of Escherichia coli and the orientation of leader peptidase in the bacterial envelope.

1983 • 307 citations

The ‘light’ and ‘medium’ subunits of the photosynthetic reaction centre from Rhodopseudomonas viridis : isolation of the genes, nucleotide and amino acid sequence

1986 • 298 citations

Thespcrtbosomal protein operon ofEschenchia coli:sequence and cotranscriptlon of the rlbosomal protein genes and a protein export gene

1983 • 258 citations

The bacteriorhodopsin gene.

1981 • 240 citations

Translocation of domains of nascent periplasmic proteins across the cytoplasmic membrane is independent of elongation

1983 • 234 citations

The atp operon: nucleotide sequence of the promoter and the genes for the membrane proteins, and the δ subunit of Escherichia coli ATP-synthase

1981 • 229 citations

Phosphate-specific transport system of Escherichia coli: nucleotide sequence and gene-polypeptide relationships

1985 • 219 citations

Sensory transducers of E. coli are composed of discrete structural and functional domains

1983 • 212 citations

Sequence of gene malG in E. coli K12: homologies between integral membrane components from binding protein-dependent transport systems.

1985 • 210 citations

ATP is essential for protein translocation into Escherichia coli membrane vesicles.

1985 • 163 citations

The nucleotide sequence of the gene for malF protein, an inner membrane component of the maltose transport system of Escherichia coli. Repeated DNA sequences are found in the malE-malF intercistronic region.

1984 • 141 citations

The structure of the lactose permease derived from Raman spectroscopy and prediction methods.

1985 • 134 citations

Structure and functional organization of light-harvesting complexes and photochemical reaction centers in membranes of phototrophic bacteria

1985 • 131 citations

M13 procoat inserts into liposomes in the absence of other membrane proteins.

1985 • 121 citations

Nucleotide sequence of the genes for β and ε subunits of proton-translocating ATPase from Escherichia coli

1982 • 119 citations

The ‘heavy’ subunit of the photosynthetic reaction centre from Rhodopseudomonas viridis : isolation of the gene, nucleotide and amino acid sequence

1985 • 116 citations

Overlap between ampC and frd operons on the Escherichia coli chromosome.

1982 • 113 citations

Structure of the Trg protein: Homologies with and differences from other sensory transducers of Escherichia coli.

1984 • 109 citations

Peptide-specific antibody locates the COOH terminus of the lactose carrier of Escherichia coli on the cytoplasmic side of the plasma membrane.

1983 • 103 citations

Molecular cloning and sequencing of the gene for CDP-diglyceride hydrolase of Escherichia coli.

1985 • 82 citations

Anti-peptide antibodies and proteases as structural probes for the lactose/proton transporter of Escherichia coli: a loop around amino acid residue 130 faces the cytoplasmic side of the membrane

1986 • 69 citations

Topological Studies of Lactose Permease ofEscherichia coliby Protein Sequence Analysis^a

1985 • 41 citations

Cloning and characterization of livH, the structural gene encoding a component of the leucine transport system in Escherichia coli

1986 • 27 citations