Inducing differentiation of transformed cells with hybrid polar compounds: a cell cycle-dependent process.

The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

1989 • 3,036 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

Mammalian G1 cyclins

1993 • 1,990 citations

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1988 • 1,490 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1991 • 1,190 citations

Formation and Activation of a Cyclin E-cdk2 Complex During the G ₁ Phase of the Human Cell Cycle

1992 • 1,046 citations

Association of human cyclin E with a periodic G1-S phase protein kinase

1992 • 900 citations

Growth inhibition by TGF-β linked to suppression of retinoblastoma protein phosphorylation

1990 • 812 citations

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

1990 • 730 citations

Erythroleukemic Differentiation

1978 • 694 citations

Negative Regulation of G1 in Mammalian Cells: Inhibition of Cyclin E-Dependent Kinase by TGF-β

1993 • 578 citations

TGFβ inhibition of Cdk4 synthesis is linked to cell cycle arrest

1993 • 544 citations

A new group of potent inducers of differentiation in murine erythroleukemia cells.

1976 • 379 citations

The cell cycle and the retinoblastoma protein family

1994 • 309 citations

Differentiation of malignant to benign cells

1971 • 306 citations

Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts.

1992 • 277 citations

Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes.

1993 • 247 citations

The retinoblastoma protein and the regulation of cell cycling

1992 • 198 citations

Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.

1977 • 193 citations

Stimulation of differentiated functions in human melanoma cells by tumor-promoting agents and dimethyl sulfoxide.

1979 • 175 citations

DP and E2F proteins: components of a heterodimeric transcription factor implicated in cell cycle control

1994 • 152 citations

Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRAD1/cyclin D1 proto-oncogene.

1992 • 150 citations

Chemically induced murine erythroleukemic differentiation

1980 • 128 citations

Hexamethylene bisacetamide in myelodysplastic syndrome and acute myelogenous leukemia: a phase II clinical trial with a differentiation- inducing agent

1992 • 124 citations

Cell differentiation and bypassing of genetic defects in the suppression of malignancy.

1987 • 118 citations

Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle.

1975 • 104 citations

Suppression of cyclin-dependent kinase 4 during induced differentiation of erythroleukemia cells.

1994 • 102 citations

Effects of differentiation‐inducing agents on maturation of human MCF‐7 breast cancer cells

1990 • 101 citations

Protein kinase C activity and hexamethylenebisacetamide-induced erythroleukemia cell differentiation.

1987 • 101 citations

Phase I clinical and pharmacokinetic study of hexamethylene bisacetamide (NSC 95580) administered as a five-day continuous infusion.

1987 • 77 citations

Murine erythroleukemia cell differentiation: relationship of globin gene expression and of prolongation of G1 to inducer effects during G1/early S.

1979 • 64 citations

Cloning of a D-type cyclin from murine erythroleukemia cells.

1992 • 64 citations

Potent cytodifferentiating agents related to hexamethylenebisacetamide.

1991 • 63 citations

Phase I trial and clinical pharmacological evaluation of hexamethylene bisacetamide administration by ten-day continuous intravenous infusion at twenty-eight-day intervals.

1988 • 60 citations

Expression and phosphorylation of the retinoblastoma protein during induced differentiation of murine erythroleukemia cells.

1992 • 54 citations

Polar/apolar compounds induce leukemia cell differentiation by modulating cell-surface potential.

1993 • 51 citations

Molecular and cellular mechanisms of leukemic hemopoietic cell differentiation: an analysis of the Friend system.

1985 • 41 citations

Erythroid colony induction without erythropoietin by Friend leukemia virus in vitro.

1975 • 40 citations

Synthesis of globin mRNA in relation to the cell cycle during induced murine erythroleukemia differentiation.

1978 • 40 citations

Differential modulation of protein kinase C isoforms in erythroleukemia during induced differentiation.

1993 • 34 citations

Polar/apolar chemical inducers of differentiation of transformed cells: strategies to improve therapeutic potential.

1989 • 29 citations

Differentiation modifiers

1984 • 27 citations

A rise and fall in 1,2-diacylglycerol content signal hexamethylene bisacetamide-induced erythropoiesis.

1992 • 22 citations