Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes.

Universal control mechanism regulating onset of M-phase

1990 • 2,882 citations

G ₁ Events and Regulation of Cell Proliferation

1989 • 2,203 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1991 • 1,190 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

Contingent Genetic Regulatory Events in T Lymphocyte Activation

1989 • 1,108 citations

Formation and Activation of a Cyclin E-cdk2 Complex During the G ₁ Phase of the Human Cell Cycle

1992 • 1,046 citations

The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element

1989 • 931 citations

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

1989 • 920 citations

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1992 • 906 citations

Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast

1991 • 846 citations

Activation of cdc2 protein kinase during mitosis in human cells: Cell cycle-dependent phosphorylation and subunit rearrangement

1988 • 786 citations

Dominoes and Clocks: the Union of Two Views of the Cell Cycle

1989 • 750 citations

Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B

1990 • 730 citations

Human D-type cyclin

1991 • 712 citations

Role of the CD28 receptor in T-cell activation

1990 • 684 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

cdc2 protein kinase is complexed with both cyclin A and B: Evidence for proteolytic inactivation of MPF

1989 • 666 citations

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family

1991 • 656 citations

An essential G1 function for cyclin-like proteins in yeast

1989 • 574 citations

Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

1991 • 541 citations

The cell biology of transforming growth factor β

1990 • 537 citations

T-Cell Proliferation Involving the CD28 Pathway Is Associated witH Cyclosporine-Resistant Interleukin 2 Gene Expression

1987 • 522 citations

The cell cycle control gene cdc2+ of fission yeast encodes a protein kinase potentially regulated by phosphorylation

1986 • 502 citations

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

1991 • 475 citations

G1-specific cyclins of S. cerevisiae: Cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase

1990 • 449 citations

Expression and function of Drosophila cyclin a during embryonic cell cycle progression

1989 • 399 citations

Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.

1985 • 370 citations

Characterization of a candidate bcl-1 gene.

1991 • 357 citations

Retinoblastoma cancer suppressor gene product is a substrate of the cell cycle regulator cdc2 kinase.

1991 • 304 citations

Selective translation of mRNA controls the pattern of protein synthesis during early development of the surf clam, Spisula solidissima

1980 • 281 citations

Deferoxamine: a reversible S-phase inhibitor of human lymphocyte proliferation

1984 • 281 citations

The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression.

1992 • 239 citations

cdc2 Gene Expression at the G ₁ to S Transition in Human T Lymphocytes

1990 • 220 citations

Hydroxyurea

1967 • 198 citations

Evidence for the involvement of three distinct signals in the induction of IL-2 gene expression in human T lymphocytes.

1989 • 117 citations

Differential regulation of the tumor suppressor molecules, retinoblastoma susceptibility gene product (Rb) and p53, during cell cycle progression of normal human T cells.

1991 • 71 citations

Differential expression of nuclear proto-oncogenes in T cells triggered with mitogenic and nonmitogenic T3 and T11 activation signals.

1987 • 53 citations

Comparison of phorbol ester/calcium ionophore and phytohemagglutinin-induced signaling in human T lymphocytes. Demonstration of interleukin 2-independent transferrin receptor gene expression.

1988 • 47 citations

Human Cell Division: The Involvement of Cyclins A and B1, and Multiple cdc2s

1991 • 26 citations

A Dubious Battle to Save the Kemp's Ridley Sea Turtle

1992 • 23 citations