Cell differentiation and bypassing of genetic defects in the suppression of malignancy.

Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences

1984 • 2,564 citations

THE GROWTH OF MOUSE BONE MARROW CELLS IN VITRO

1966 • 1,944 citations

CELLULAR ONCOGENES AND RETROVIRUSES

1983 • 1,671 citations

Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus

1983 • 1,657 citations

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1

1985 • 1,590 citations

Simian Sarcoma Virus onc Gene, v- sis , Is Derived from the Gene (or Genes) Encoding a Platelet-Derived Growth Factor

1983 • 1,550 citations

Recombinant Human Granulocyte Colony-Stimulating Factor: Effects on Normal and Leukemic Myeloid Cells

1986 • 1,260 citations

Cellular Oncogenes and Multistep Carcinogenesis

1983 • 1,154 citations

The Granulocyte-Macrophage Colony-Stimulating Factors

1985 • 1,007 citations

The cloning of normal “Mast” cells in tissue culture

1965 • 886 citations

Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor

1986 • 831 citations

Survival of mononuclear phagocytes depends on a lineage-specific growth factor that the differentiated cells selectively destroy

1982 • 671 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

Induction of differentiation of human acute myelogenous leukemia cells: therapeutic implications

1983 • 585 citations

Molecular Cloning of a Complementary DNA Encoding Human Macrophage-Specific Colony-Stimulating Factor (CSF-1)

1985 • 542 citations

Retinoblastoma: Clues to Human Oncogenesis

1984 • 495 citations

Molecular cloning of cDNA for murine interleukin-3

1984 • 485 citations

Molecular cloning of cDNA encoding a murine haematopoietic growth regulator, granulocyte—macrophage colony stimulating factor

1984 • 451 citations

<italic>In Vitro</italic> Transformation of Normal Cells to Tumor Cells by Carcinogenic Hydrocarbons<xref ref-type="fn" rid="FN2">2</xref>

1965 • 400 citations

Chemotaxis and inflammation

1974 • 397 citations

In vitro control of the development of macrophage and granulocyte colonies.

1966 • 385 citations

Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells.

1984 • 365 citations

The induction of clones of normal mast cells by a substance from conditioned medium

1966 • 358 citations

Human Cell Hybrids: Analysis of Transformation and Tumorigenicity

1982 • 349 citations

Purification and some characteristics of human T-cell growth factor from phytohemagglutinin-stimulated lymphocyte-conditioned media.

1980 • 291 citations

Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes.

1983 • 221 citations

Different Blocks in the Differentiation of Myeloid Leukemic Cells

1974 • 191 citations

Constitutive uncoupling of pathways of gene expression that control growth and differentiation in myeloid leukemia: a model for the origin and progression of malignancy.

1980 • 189 citations

In Vitro Cell Transformation by X-Irradiation

1966 • 185 citations

Formation of Pure Suspensions of Mast Cells in Tissue Culture by Differentiation of Lymphoid Cells From the Mouse Thymus<xref ref-type="fn" rid="FN2">2</xref>

1963 • 147 citations

Control of the Reversion of Properties in Transformed Cells

1970 • 133 citations

Tumorigenicity of human HT1080 fibrosarcoma X normal fibroblast hybrids: chromosome dosage dependency.

1984 • 130 citations

Chromosome mapping of the genes that control differentiation and malignancy in myeloid leukemic cells.

1977 • 129 citations

Reversion of Properties in Cells transformed by Polyoma Virus

1968 • 128 citations

Successive generations of mice produced from an established culture line of euploid teratocarcinoma cells

1981 • 128 citations

In vivo inhibition of the development of myeloid leukemia by injection of macrophage‐and granulocyte‐inducing protein

1981 • 110 citations

Participation of myeloid leukaemic cells injected into embryos in haematopoietic differentiation in adult mice

1982 • 110 citations

Identification of the Chromosomes that Control Malignancy

1973 • 106 citations

Isolation and characterization of a T lymphocyte-derived differentiation inducing factor for the myeloid leukemic cell line HL- 60

1984 • 100 citations

Regulation of membrane changes, differentiation, and malignancy in carcinogenesis.

1974 • 100 citations

The analysis of malignancy by cell fusion IX.* Re-examination and clarification of the cytogenetic problem

1982 • 94 citations

Suppression of tumorigenicity in hybrids of normal and oncogene-transformed CHEF cells.

1985 • 91 citations

Growth, Differentiation and the Reversal of Malignancy

1986 • 89 citations

Cell susceptibility to transformation by x-irradiation and fixation of the transformed state.

1967 • 88 citations

Mechanisms that uncouple growth and differentiation in myeloid leukemia cells: restoration of requirement for normal growth-inducing protein without restoring induction of differentiation-inducing protein.

1982 • 77 citations

Tumorigenicity of embryonal carcinoma as an assay to study control of malignancy by the murine blastocyst.

1979 • 62 citations

Developmental potential of myeloid leukemia cells injected into midgestation embryos

1984 • 60 citations

Coupling of growth and differentiation in normal myeloid precursors and the breakdown of this coupling in leukemia

1983 • 59 citations

In vitro differentiation of Rauscher‐virus‐induced myeloid leukemia cells

1976 • 53 citations

Chromosome balance and the control of malignancy

1976 • 49 citations

The phenomenon of differentiation in murine erythroleukemic cells.

1978 • 47 citations

Regulation of cell surface receptors for different hematopoietic growth factors on myeloid leukemic cells.

1986 • 42 citations

The formation of variants with a reversion of properties of transformed cells. V. Reversion to a limited life‐span

1970 • 41 citations

Constitutive gene expression in myeloid leukemia and cell competence for induction of differentiation by the steroid dexamethasone.

1981 • 36 citations

Autoinduction of differentiation in myeloid leukemic cells: restoration of normal coupling between growth and differentiation in leukemic cells that constitutively produce their own growth-inducing protein.

1982 • 30 citations

DNA-binding protein that induces cell differentiation.

1983 • 28 citations

Genetic analysis of tumorigenesis: X. Chromosome studies of transformed mutants and tumor-derived CHEF/18 cells

1982 • 20 citations

Activation of normal genes in malignant cells: Activation of chemotaxis in relation to other stages of normal differentiation in myeloid leukemia

1979 • 19 citations

Protein that induces cell differentiation causes nicks in double‐stranded DNA

1986 • 16 citations

Control of in-vivo differentiation of myeloid leukemic cells— V. Regulation by response to antigen

1985 • 15 citations

Synchrony of gene expression and the differentiation of myeloid leukemic cells: reversion from constitutive to inducible protein synthesis.

1983 • 15 citations

Cell competence for industion of differentiation by insulin and other compounds in myeloid leukemic clones continuously cultured in serum- free medium

1982 • 11 citations

Multimeric complexes of differentiation-inducing protein bound to DNA.

1985 • 9 citations