Differential kinetics of effector and regulatory T cells in patients on calcineurin inhibitor–based drug regimens

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

2006 • 2,516 citations

A function for interleukin 2 in Foxp3-expressing regulatory T cells

2005 • 1,744 citations

Regulatory T cells in transplantation tolerance

2003 • 1,323 citations

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells

2005 • 1,090 citations

Transient expression of FOXP3 in human activated nonregulatory CD4⁺ T cells

2006 • 973 citations

Deregulated T Cell Activation and Autoimmunity in Mice Lacking Interleukin-2 Receptor β

1995 • 868 citations

Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

2007 • 836 citations

Tolerance, not immunity, crucially depends on IL-2

2004 • 826 citations

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

2001 • 799 citations

CD4 Regulatory T Cells Prevent Lethal Autoimmunity in IL-2Rβ-Deficient Mice

2002 • 783 citations

CD4+CD25+ T Cells Regulate Virus-specific Primary and Memory CD8+ T Cell Responses

2003 • 531 citations

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

2006 • 497 citations

Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling

2005 • 473 citations

T Cells with a CD4⁺CD25⁺Regulatory Phenotype Suppress In Vitro Proliferation of Virus-Specific CD8⁺T Cells during Chronic Hepatitis C Virus Infection

2005 • 403 citations

Molecular Mechanisms Underlying FOXP3 Induction in Human T Cells

2006 • 394 citations

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

2005 • 378 citations

Multiparameter Immune Profiling of Operational Tolerance in Liver Transplantation

2007 • 357 citations

Regulatory T cells and cancer

2007 • 325 citations

Contrasting CD25hiCD4+T Cells/FOXP3 Patterns in Chronic Rejection and Operational Drug-Free Tolerance

2006 • 269 citations

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location.

1993 • 264 citations

Regulatory T cells in virus infections

2006 • 254 citations

Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells

2005 • 248 citations

LEVELS OF VIRUS-SPECIFIC CD4 T CELLS CORRELATE WITH CYTOMEGALOVIRUS CONTROL AND PREDICT VIRUS-INDUCED DISEASE AFTER RENAL TRANSPLANTATION1

2001 • 247 citations

Calcineurin Inhibitors, but not Rapamycin, Reduce Percentages of CD4+CD25+FOXP3+ Regulatory T Cells in Renal Transplant Recipients

2006 • 245 citations

The complementary roles of deletion and regulation in transplantation tolerance

2003 • 238 citations

Regulatory T Cells and T Cell Depletion

2007 • 229 citations

The Effect of Costimulatory and Interleukin 2 Receptor Blockade on Regulatory T Cells in Renal Transplantation

2008 • 226 citations

Differential Effect of Calcineurin Inhibitors, Anti-CD25 Antibodies and Rapamycin on the Induction of FOXP3 in Human T Cells

2005 • 220 citations

Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART

2006 • 207 citations

CD4+CD25+FOXP3+ Regulatory T Cells Increase De Novo in Kidney Transplant Patients After Immunodepletion with Campath-1H

2008 • 169 citations

Infectious tolerance and the long‐term acceptance of transplanted tissue

2006 • 168 citations

PD-1 Expression and IL-2 Loss of Cytomegalovirus- Specific T Cells Correlates with Viremia and Reversible Functional Anergy

2008 • 161 citations

Differences in CMV-Specific T-Cell Levels and Long-Term Susceptibility to CMV Infection after Kidney, Heart and Lung Transplantation

2005 • 150 citations

CD4⁺CD25⁺T Cells Regulate Vaccine-Generated Primary and Memory CD8⁺T-Cell Responses against Herpes Simplex Virus Type 1

2004 • 148 citations

Impact of Immunosuppressive Drugs on CD4+CD25+FOXP3+ Regulatory T Cells: Does In Vitro Evidence Translate to the Clinical Setting?

2008 • 102 citations

Following Anti-CD25 Treatment, A Functional CD4+CD25+ Regulatory T-Cell Pool Is Present in Renal Transplant Recipients

2006 • 90 citations

Age‐Related Decrease in Adenovirus‐Specific T Cell Responses

2002 • 67 citations

Improved efficiency in detecting cellular immunity towards M. tuberculosis in patients receiving immunosuppressive drug therapy

2006 • 48 citations

Effect of Anti‐IL‐2Rα Antibody on IL‐2‐induced Jak/STAT Signaling

2002 • 32 citations

Regulatory T Cells in Transplantation Tolerance

2005 • 17 citations