CD4+CD25+FOXP3+ Regulatory T Cells Increase De Novo in Kidney Transplant Patients After Immunodepletion with Campath-1H

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

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Reshaping human antibodies for therapy

1988 • 1,555 citations

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2001 • 1,168 citations

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2007 • 836 citations

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2001 • 658 citations

Inhibition of CD4+CD25+ regulatory T-cell function by calcineurin-dependent interleukin-2 production

2006 • 497 citations

Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo

2006 • 474 citations

Immunocompetent T-Cells with a Memory-Like Phenotype are the Dominant Cell Type Following Antibody-Mediated T-Cell Depletion

2005 • 459 citations

Campath-1H Induction Plus Rapamycin Monotherapy for Renal Transplantation: Results of a Pilot Study

2003 • 379 citations

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

2005 • 378 citations

CD25− T Cells Generate CD25+Foxp3+ Regulatory T Cells by Peripheral Expansion

2004 • 373 citations

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2006 • 365 citations

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2006 • 333 citations

CAMPATH IH ALLOWS LOW-DOSE CYCLOSPORINE MONOTHERAPY IN 31 CADAVERIC RENAL ALLOGRAFT RECIPIENTS

1999 • 306 citations

Sequential development of interleukin 2–dependent effector and regulatory T cells in response to endogenous systemic antigen

2005 • 296 citations

De novogeneration of antigen-specific CD4⁺CD25⁺regulatory T cells from human CD4⁺CD25^–cells

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Role of IFN-g in induction of Foxp3 and conversion of CD4+CD25- T cells to CD4+ Tregs

2006 • 271 citations

Conversion of CD4+ CD25− cells into CD4+ CD25+ regulatory T cells in vivo requires B7 costimulation, but not the thymus

2005 • 271 citations

Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells

2005 • 248 citations

Calcineurin Inhibitors, but not Rapamycin, Reduce Percentages of CD4+CD25+FOXP3+ Regulatory T Cells in Renal Transplant Recipients

2006 • 245 citations

Regulatory T Cells and T Cell Depletion

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2004 • 227 citations

Alemtuzumab (CAMPATH 1H) Induction Therapy in Cadaveric Kidney Transplantation―Efficacy and Safety at Five Years

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Differential Effect of Calcineurin Inhibitors, Anti-CD25 Antibodies and Rapamycin on the Induction of FOXP3 in Human T Cells

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2006 • 189 citations

Wiskott-Aldrich syndrome protein is required for regulatory T cell homeostasis

2007 • 186 citations

Alemtuzumab Induction and Prednisone‐Free Maintenance Immunotherapy in Kidney Transplantation: Comparison with Basiliximab Induction—Long‐Term Results

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In vitro expanded human CD4+CD25+ regulatory T cells suppress effector T cell proliferation

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Use of Alemtuzumab and Tacrolimus Monotherapy for Cadaveric Liver Transplantation: With Particular Reference to Hepatitis C Virus

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2004 • 148 citations

Naturally Arising Foxp3-Expressing CD25+CD4+ Regulatory T Cells in Self-Tolerance and Autoimmune Disease

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Peripheral blood but not tissue dendritic cells express CD52 and are depleted by treatment with alemtuzumab

2002 • 135 citations

Alemtuzumab Induction and Prednisone-Free Maintenance Immunotherapy in Simultaneous Pancreas-Kidney Transplantation Comparison With Rabbit Antithymocyte Globulin Induction – Long-Term Results

2005 • 135 citations

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Alemtuzumab induces caspase-independent cell death in human chronic lymphocytic leukemia cells through a lipid raft-dependent mechanism

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Following Anti-CD25 Treatment, A Functional CD4+CD25+ Regulatory T-Cell Pool Is Present in Renal Transplant Recipients

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2002 • 50 citations

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2001 • 48 citations

Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?

2002 • 43 citations

Prope tolerance with induction using Campath 1H and low-dose cyclosporin monotherapy in 31 cadaveric renal allograft recipients.

2000 • 29 citations

Campath-1H immunosuppressive therapy reduces incidence and intensity of acute rejection in intestinal and multivisceral transplantation

2004 • 29 citations

Non-specific immunosuppressants in the treatment of multiple sclerosis

2004 • 27 citations

A Novel Costimulation Pathway Via the 4C8 Antigen for the Induction of CD4+ Regulatory T Cells

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Different glycoforms of the human GPI-anchored antigen CD52 associate differently with lipid microdomains in leukocytes and sperm membranes

2005 • 22 citations

Treatment of refractory autoimmune diseases with ablative immunotherapy

2003 • 20 citations

Impaired TCR-Mediated Induction of Ki67 by Naive CD4+ T Cells Is Only Occasionally Corrected by Exogenous IL-2 in HIV-1 Infection

2003 • 20 citations

Competition controls the rate of transition between the peripheral pools of CD4+CD25- and CD4+CD25+ T cells

2006 • 19 citations

CD4⁺CD25⁺regulatory T cell therapy for the induction of donor-specific clinical transplantation tolerance

2006 • 6 citations

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