Tea polyphenols for health promotion

Tea Catechins and Polyphenols: Health Effects, Metabolism, and Antioxidant Functions

2003 • 1,796 citations

Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

1995 • 1,769 citations

Antioxidant Capacity of Tea and Common Vegetables

1996 • 1,332 citations

Tea and Cancer

1993 • 1,012 citations

Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans

1999 • 929 citations

Tea polyphenols: prevention of cancer and optimizing health

2000 • 893 citations

Chemoprevention of Human Prostate Cancer by Oral Administration of Green Tea Catechins in Volunteers with High-Grade Prostate Intraepithelial Neoplasia: A Preliminary Report from a One-Year Proof-of-Principle Study

2006 • 805 citations

Targeting Multiple Signaling Pathways by Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate

2006 • 792 citations

Blood and urine levels of tea catechins after ingestion of different amounts of green tea by human volunteers.

1998 • 570 citations

Risk factors for hip fracture in european women: The MEDOS study

1995 • 561 citations

Modulation of Endocrine Systems and Food Intake by Green Tea Epigallocatechin Gallate*

2000 • 513 citations

Beneficial effects of tea catechins on diet-induced obesity: stimulation of lipid catabolism in the liver

2002 • 512 citations

Inhibition of prostate carcinogenesis in TRAMP mice by oral infusion of green tea polyphenols

2001 • 492 citations

Mechanisms of Cancer Prevention by Tea Constituents

2003 • 483 citations

Green tea and thermogenesis: interactions between catechin-polyphenols, caffeine and sympathetic activity

2000 • 436 citations

Antioxidants in tea

1997 • 428 citations

Preventive effects of drinking green tea on cancer and cardiovascular disease: Epidemiological evidence for multiple targeting prevention

2000 • 416 citations

Epigallocatechin gallate attenuates diet-induced obesity in mice by decreasing energy absorption and increasing fat oxidation

2005 • 415 citations

Flavonoid intake and long-term risk of coronary heart disease and cancer in the seven countries study

1995 • 394 citations

Effect of EGCG on lipid absorption and plasma lipid levels in rats

2003 • 393 citations

Protective effect of green tea against prostate cancer: A case‐control study in southeast China

2003 • 378 citations

Prevention of collagen-induced arthritis in mice by a polyphenolic fraction from green tea

1999 • 374 citations

Does Tea Affect Cardiovascular Disease? A Meta-Analysis

2001 • 363 citations

Inhibition of tobacco-specific nitrosamine-induced lung tumorigenesis in A/J mice by green tea and its major polyphenol as antioxidants

1993 • 356 citations

A single dose of tea with or without milk increases plasma antioxidant activity in humans

2000 • 353 citations

Risk Factors for Hip Fracture in Men from Southern Europe: The MEDOS Study

1999 • 348 citations

(−)-Epigallocatechin Gallate and Polyphenon E Inhibit Growth and Activation of the Epidermal Growth Factor Receptor and Human Epidermal Growth Factor Receptor-2 Signaling Pathways in Human Colon Cancer Cells

2005 • 346 citations

Cancer chemopreventive activity and bioavailability of tea and tea polyphenols

2003 • 343 citations

L-theanine—a unique amino acid of green tea and its relaxation effect in humans

1999 • 341 citations

Multifunctional Activities of Green Tea Catechins in Neuroprotection

2005 • 338 citations

Tea, obesity, and diabetes

2006 • 319 citations

Role of p53 and NF-κB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells

2003 • 317 citations

Black and Green Tea Polyphenols Attenuate Blood Pressure Increases in Stroke-Prone Spontaneously Hypertensive Rats

2004 • 317 citations

Influence of Drinking Green Tea on Breast Cancer Malignancy among Japanese Patients

1998 • 308 citations

Chemistry and Applications of Green Tea

1997 • 307 citations

Molecular pathway for (−)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells

2003 • 302 citations

Mechanisms of hypolipidemic and anti‐obesity effects of tea and tea polyphenols

2006 • 300 citations

Oral Consumption of Green Tea Polyphenols Inhibits Insulin-Like Growth Factor-I–Induced Signaling in an Autochthonous Mouse Model of Prostate Cancer

2004 • 296 citations

Tea drinking and bone mineral density in older women

2000 • 288 citations

Antioxidative properties of black tea

2004 • 286 citations

Green tea catechins as brain‐permeable, natural iron chelators‐antioxidants for the treatment of neurodegenerative disorders

2006 • 280 citations

Structural Identification of Two Metabolites of Catechins and Their Kinetics in Human Urine and Blood after Tea Ingestion

2000 • 275 citations

Molecular Targets for Green Tea in Prostate Cancer Prevention

2003 • 259 citations

Green tea and risk of breast cancer in Asian Americans

2003 • 244 citations

Coffee and Tea Intake and the Risk of Myocardial Infarction

1999 • 241 citations

Tea Flavonoids May Protect Against Atherosclerosis

1999 • 240 citations

Anti-proliferative and proapoptotic effects of (?)-epigallocatechin-3-gallate on human melanoma: Possible implications for the chemoprevention of melanoma

2004 • 236 citations

The role of tea and tea flavonoids in cardiovascular health

2006 • 235 citations

Plasma and Tissue Levels of Tea Catechins in Rats and Mice During Chronic Consumption of Green Tea Polyphenols

2000 • 234 citations

Green tea consumption and the risk of pancreatic and colorectal cancers

1997 • 231 citations

Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies

2005 • 228 citations

Green tea extracts decrease carcinogen‐induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture

2001 • 226 citations

Effectiveness of moderate green tea consumption on antioxidative status and plasma lipid profile in humans

2005 • 218 citations

Inhibition of Intestinal Tumorigenesis in Apcmin/+ Mice by (−)-Epigallocatechin-3-Gallate, the Major Catechin in Green Tea

2005 • 215 citations

Epigallocatechin-3-gallate induces mitochondrial membrane depolarization and caspase-dependent apoptosis in pancreatic cancer cells

2005 • 212 citations

Combined Inhibitory Effects of Green Tea Polyphenols and Selective Cyclooxygenase-2 Inhibitors on the Growth of Human Prostate Cancer Cells Both In vitro and In vivo

2007 • 202 citations

Suppression of Wnt Signaling by the Green Tea Compound (–)-Epigallocatechin 3-Gallate (EGCG) in Invasive Breast Cancer Cells

2006 • 201 citations

A New Function of Green Tea: Prevention of Lifestyle‐related Diseases

2001 • 196 citations

Tea Consumption and Mortality After Acute Myocardial Infarction

2002 • 195 citations

Modulation of Endocrine Systems and Food Intake by Green Tea Epigallocatechin Gallate

2000 • 183 citations

Green, oolong and black tea extracts modulate lipid metabolism in hyperlipidemia rats fed high-sucrose diet

2001 • 182 citations

Protection against polycyclic aromatic hydrocarbon-induced skin tumor initiation in mice by green tea polyphenols

1989 • 180 citations

Scavenging mechanisms of (-)-epigallocatechin gallate and (-)-epicatechin gallate on peroxyl radicals and formation of superoxide during the inhibitory action

1999 • 175 citations

Ablation of either p21 or Bax prevents p53‐dependent apoptosis induced by green tea polyphenol epigallocatechin‐3‐gallate

2005 • 170 citations

Tea intake, COMT genotype, and breast cancer in Asian-American women.

2003 • 169 citations

Tea and Health: The Underlying Mechanisms

1999 • 166 citations

Growth Inhibitory and Antimetastatic Effect of Green Tea Polyphenols on Metastasis-Specific Mouse Mammary Carcinoma 4T1 Cells In vitro and In vivo Systems

2005 • 156 citations

Glucuronidation and Sulfation of the Tea Flavonoid (−)-Epicatechin by the Human and Rat Enzymes

2002 • 155 citations

Orally Administered Green Tea Polyphenols Prevent Ultraviolet Radiation-Induced Skin Cancer in Mice through Activation of Cytotoxic T Cells and Inhibition of Angiogenesis in Tumors

2005 • 150 citations

Protective effect of epigallocatechin gallate on brain damage after transient middle cerebral artery occlusion in rats

2004 • 143 citations

Relation between Green Tea Consumption and the Severity of Coronary Atherosclerosis among Japanese Men and Women

2000 • 139 citations

Cancer Chemoprevention: Future Holds in Multiple Agents

1999 • 138 citations

Effects of black tea, green tea and wine extracts on intestinal carcinogenesis induced by azoxymethane in F344 rats

2000 • 138 citations

Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice

2003 • 134 citations

Soy Phytochemicals and Tea Bioactive Components Synergistically Inhibit Androgen-Sensitive Human Prostate Tumors in Mice

2003 • 133 citations

A Population-Based Case-Control Study of Lung Cancer and Green Tea Consumption among Women Living in Shanghai, China

2001 • 117 citations

Effect of a Thermogenic Beverage on 24‐Hour Energy Metabolism in Humans

2007 • 117 citations

Inhibitory effects and toxicity of green tea polyphenols for gastrointestinal carcinogenesis

1996 • 117 citations

Hypolipidemic Effect of Green Tea Leaves through Induction of Antioxidant and Phase II Enzymes Including Superoxide Dismutase, Catalase, and Glutathione S-Transferase in Rats

1998 • 104 citations

Absorption of Tea Catechins into Rat Portal Vein.

1996 • 102 citations

The Effect of Tea Consumption on Oxidative Stress in Smokers and Nonsmokers

1999 • 99 citations

Inhibitory effect of black tea on the growth of established skin tumors in mice: effects on tumor size, apoptosis, mitosis and bromodeoxyuridine incorporation into DNA

1997 • 99 citations

Combination cancer chemoprevention with green tea extract and sulindac shown in intestinal tumor formation in Min mice

2001 • 95 citations

Inhibition of spontaneous formation of lung tumors and rhabdomyosarcomas in A/J mice by black and green tea

1998 • 95 citations

Inhibition of lung carcinogenesis by black tea in Fischer rats treated with a tobacco-specific carcinogen: caffeine as an important constituent.

1998 • 94 citations

Green tea extract decreases plasma malondialdehyde concentration but does not affect other indicators of oxidative stress, nitric oxide production, or hemostatic factors during a high-linoleic acid diet in healthy females

1999 • 94 citations

Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis model with A/J mice.

1997 • 89 citations

Prostate carcinoma and green tea: PSA‐triggered basement membrane degradation and MMP‐2 activation are inhibited by (−)epigallocatechin‐3‐gallate

2004 • 77 citations

Inhibitory Effect of Green and Black Tea on Tumor Growth

1999 • 72 citations

Inhibition of CWR22Rν1 tumor growth and PSA secretion in athymic nude mice by green and black teas

2005 • 72 citations

Consumption of tea and coffee and the risk of lung cancer in cigarette-smoking men: a case-control study in Uruguay

1998 • 70 citations

Protection against induction of mouse skin papillomas with low and high risk of conversion to malignancy by green tea polyphenols

1997 • 70 citations

Japanese Green Tea as a Cancer Preventive in Humans

2009 • 68 citations

Suppression of Human Pancreatic Carcinoma Cell Growth and Invasion by Epigallocatechin-3-Gallate

2002 • 67 citations

Dietary habits and lung cancer risk among non-smoking women

2004 • 66 citations

Is green tea good for HIV-1 infection?

2003 • 66 citations

Risk of melanoma and vitamin A, coffee and alcohol: a case–control study from Italy

2004 • 65 citations

In Vitro and in Vivo Antimicrobial Action of Tea: The Commonest Beverage of Asia

2005 • 65 citations

Modulation of N-methyl-N-nitrosourea induced mammary tumors in Sprague–Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract

2005 • 65 citations

Profiles of Potentially Antiallergic Flavonoids in 27 Kinds of Health Tea and Green Tea Infusions

1997 • 64 citations

Inhibitory effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ), green tea catechins and other antioxidants on 2-amino-6-methyldipyrido[l,2-a: 3′ ,2′ -d]imidazole (Glu-P-1)-induced rat hepatocarcinogenesis and dose-dependent inhibition by HTHQ of lesion induction by Glu-P-1 or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)

1995 • 63 citations

Comparison of green tea intake in Japanese patients with and without angiographic coronary artery disease

2002 • 62 citations

Prognostic Significance of Metastasis-Associated Protein S100A4 (Mts1) in Prostate Cancer Progression and Chemoprevention Regimens in an Autochthonous Mouse Model

2005 • 62 citations

Prevention of dual promoting effects of pentachlorophenol, an environmental pollutant, on diethylnitrosamine-induced hepato- and cholangiocarcinogenesis in mice by green tea infusion

2003 • 61 citations

Black tea polyphenols suppress cell proliferation and induce apoptosis during benzo(a)pyrene-induced lung carcinogenesis

2005 • 60 citations

Inhibitory Effects of Tea Catechins, Black Tea Extract and Oolong Tea Extract on Hepatocarcinogenesis in Rat

1996 • 57 citations

Tea Preparations Protect Against DMBA-Induced Oral Carcinogenesis in Hamsters

1999 • 57 citations

Administration of green tea or caffeine enhances the disappearance of UVB-induced patches of mutant p53 positive epidermal cells in SKH-1 mice

2005 • 52 citations

Inhibitory Effects of β-Carotene, Palm Carotene, and Green Tea Polyphenols on Pancreatic Carcinogenesis Initiated by N-Nitrosobis(2-oxopropy1)amine in Syrian Golden Hamsters

1998 • 51 citations

Joint effects of citrus peel use and black tea intake on the risk of squamous cell carcinoma of the skin

2001 • 50 citations

Can teatime increase one’s lifetime?

2002 • 47 citations

[A case-control study on drinking green tea and decreasing risk of cancers in the alimentary canal among cigarette smokers and alcohol drinkers].

2003 • 47 citations

Inhibition of urinary bladder tumors induced by N‐butyl‐N‐(4‐hydroxybutyl)‐nitrosamine in rats by green tea

1999 • 44 citations

[A case-control study on the dietary risk factors of upper digestive tract cancer].

1999 • 43 citations

Inhibitory effects and toxicity of green tea polyphenols for gastrointestinal carcinogenesis

1996 • 42 citations

Effects of tea on preneoplastic lesions and cell cycle regulators in rat liver.

2002 • 38 citations

A Gene Expression Signature that Can Predict Green Tea Exposure and Chemopreventive Efficacy of Lung Cancer in Mice

2006 • 36 citations

Insulin-Like Growth Factor-I Axis as a Pathway for Cancer Chemoprevention

2006 • 35 citations

Glucose-lowering effect of powder formulation of African black tea extract in KK-Ay/TaJcl diabetic mouse

2006 • 33 citations

Inhibitory Effect of Green Tea Extract on the Process of Pancreatic Carcinogenesis Induced by N-Nitrosobis-(2-oxypropyl)amine (BOP) and on Tumor Promotion After Transplantation of N-Nitrosobis-(2-hydroxypropyl)amine (BHP)-Induced Pancreatic Cancer in Syrian Hamsters

1997 • 30 citations

Potential therapeutic applications of tea in dermatology

1999 • 29 citations

Dietary green tea intake preserves and improves arterial compliance and endothelial function

2003 • 10 citations

Proconvulsive effect of tea (Camellia sinensis) in mice

1999 • 10 citations

Proconvulsive effect of tea (Camellia sinensis) in mice

1999 • 10 citations