The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

2000 • 15,583 citations

Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer

2004 • 4,315 citations

Epigenetics in human disease and prospects for epigenetic therapy

2004 • 3,142 citations

Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases

2004 • 2,355 citations

DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

2001 • 2,050 citations

Free DNA in the serum of cancer patients and the effect of therapy.

1977 • 1,708 citations

MethyLight: a high-throughput assay to measure DNA methylation

2000 • 1,382 citations

A Pooled Analysis of Bone Marrow Micrometastasis in Breast Cancer

2005 • 1,333 citations

Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer

2005 • 1,092 citations

Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.

1999 • 920 citations

Circulating tumor cells (CTC) detection: Clinical impact and future directions

2007 • 916 citations

Gene promoter hypermethylation in tumors and serum of head and neck cancer patients.

2000 • 540 citations

Detection of aberrant p16 methylation in the plasma and serum of liver cancer patients.

1999 • 507 citations

Detection and Clinical Importance of Micrometastatic Disease

1999 • 505 citations

Epigenetic patterns in the progression of esophageal adenocarcinoma.

2001 • 502 citations

DNA methylation and breast carcinogenesis

2002 • 452 citations

The Origin and Mechanism of Circulating DNA

2000 • 370 citations

DNA methylation in serum of breast cancer patients: an independent prognostic marker.

2003 • 319 citations

Association of Breast Cancer DNA Methylation Profiles with Hormone Receptor Status and Response to Tamoxifen

2004 • 308 citations

Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.

2002 • 301 citations

Fluorescent methylation-specific polymerase chain reaction for DNA-based detection of prostate cancer in bodily fluids.

2000 • 275 citations

Predictive and Prognostic Value of Peripheral Blood Cytokeratin-19 mRNA-Positive Cells Detected by Real-Time Polymerase Chain Reaction in Node-Negative Breast Cancer Patients

2006 • 267 citations

HER2-Positive Circulating Tumor Cells Indicate Poor Clinical Outcome in Stage I to III Breast Cancer Patients

2006 • 261 citations

Detection of Aberrant Methylation of Four Genes in Plasma DNA for the Detection of Breast Cancer

2006 • 244 citations

Circulating Tumor-Specific DNA: A Marker for Monitoring Efficacy of Adjuvant Therapy in Cancer Patients

2005 • 239 citations

Presence of tumor DNA in plasma of breast cancer patients: clinicopathological correlations.

1999 • 238 citations

Quantitative Assessment of Promoter Hypermethylation during Breast Cancer Development

2002 • 221 citations

Quantitative Detection of Promoter Hypermethylation of Multiple Genes in the Tumor, Urine, and Serum DNA of Patients With Renal Cancer

2005 • 190 citations

Detection of Promoter Hypermethylation of Multiple Genes in the Tumor and Bronchoalveolar Lavage of Patients with Lung Cancer

2004 • 169 citations

Correlation between CpG methylation profiles and hormone receptor status in breast cancers

2007 • 153 citations

Quantitative analysis of plasma circulating DNA at diagnosis and during follow-up of breast cancer patients

2006 • 138 citations

DNA Methylation in Serum and Tumors of Cervical Cancer Patients

2004 • 132 citations

Aberrant DNA methylation of the p16INK4a gene in plasma DNA of breast cancer patients

1999 • 131 citations

Methods for isolating circulating epithelial cells and criteria for their classification as carcinoma cells

2005 • 113 citations

Estrogen receptor and HER2/neu status affect epigenetic differences of tumor-related genes in primary breast tumors

2008 • 111 citations

Quantitation of circulating DNA in the serum of breast cancer patients by real-time PCR

2004 • 110 citations

Association of Circulating Tumor Cells with Serum Tumor-Related Methylated DNA in Peripheral Blood of Melanoma Patients

2006 • 100 citations

DNA methylation, nuclear structure, gene expression and cancer

2000 • 98 citations

Detection of Mammaglobin A-mRNA-positive circulating tumor cells in peripheral blood of patients with operable breast cancer with nested RT-PCR

2006 • 86 citations

Detection of hypermethylated genes in tumor and plasma of cervical cancer patients

2004 • 80 citations

Pitfalls in the detection of disseminated non-hematological tumor cells

2000 • 67 citations

Prognostic significance of circulating tumour cells enumerated after filtration enrichment in early and metastatic breast cancer patients

2006 • 66 citations

Detection and Characterization of Circulating Microsatellite‐DNA in Blood of Patients with Breast Cancer

2004 • 57 citations

Breast Cancer–Specific mRNA Transcripts Presence in Peripheral Blood After Adjuvant Chemotherapy Predicts Poor Survival Among High-Risk Breast Cancer Patients Treated With High-Dose Chemotherapy With Peripheral Blood Stem Cell Support

2006 • 39 citations

Methylated NEUROD1 Promoter is a Marker for Chemosensitivity in Breast Cancer

2008 • 38 citations

Prognostic Significance of Disseminated Tumor Cells as Detected by Quantitative Real-Time Reverse-Transcriptase Polymerase Chain Reaction in Patients with Breast Cancer

2006 • 30 citations

Microsatellite Alterations Detected in the Serum of Early Stage Breast Cancer Patients

2001 • 30 citations

Detection of circulating epithelial cells after surgery for benign breast disease.

2000 • 22 citations

CA 15-3 et cancers du sein

1994 • 7 citations