BMP-2 induces ectopic expression of cardiac lineage markers and interferes with somite formation in chicken embryos

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Requirement of the transcription factor GATA4 for heart tube formation and ventral morphogenesis.

1997 • 1,138 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation.

1997 • 1,031 citations

Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development

1996 • 959 citations

The gene tinman is required for specification of the heart and visceral muscles in Drosophila

1993 • 790 citations

Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

1995 • 784 citations

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer

1996 • 757 citations

MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways

1996 • 710 citations

A role for bone morphogenetic proteins in the induction of cardiac myogenesis.

1997 • 687 citations

GATA-4/5/6, a subfamily of three transcription factors transcribed in developing heart and gut.

1994 • 567 citations

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

1994 • 553 citations

Cloning and characterization of a human type II receptor for bone morphogenetic proteins.

1995 • 551 citations

A New Technique for the Cultivation of the Chick Embryo in vitro

1955 • 530 citations

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.

1995 • 510 citations

Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells

1994 • 495 citations

Maternal Rescue of Transforming Growth Factor-β 1 Null Mice

1994 • 494 citations

Molecular Pathways Controlling Heart Development

1996 • 485 citations

Induction of avian cardiac myogenesis by anterior endoderm

1995 • 475 citations

Evidence for Involvement of Activin A and Bone Morphogenetic Protein 4 in Mammalian Mesoderm and Hematopoietic Development

1995 • 464 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

Induction of visceral and cardiac mesoderm by ectodermal Dpp in the early Drosophila embryo

1995 • 419 citations

Lateral and Axial Signals Involved in Avian Somite Patterning: A Role for BMP4

1996 • 416 citations

Pax-3 expression in segmental mesoderm marks early stages in myogenic cell specification

1994 • 372 citations

Primitive-Streak Origin of the Cardiovascular System in Avian Embryos

1993 • 362 citations

Control of cell pattern in the neural tube: Regulation of cell differentiation by dorsalin-1, a novel TGFβ family member

1993 • 320 citations

Features of embryonic induction

1988 • 271 citations

The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation

1997 • 253 citations

An inductive role for the endoderm in Xenopus cardiogenesis

1995 • 234 citations

Combined BMP-2 and FGF-4, but Neither Factor Alone, Induces Cardiogenesis in Non-Precardiac Embryonic Mesoderm

1996 • 224 citations

Embryonic Patterning: To BMP or Not to BMP, That Is the Question

1997 • 221 citations

Heart Development in Drosophila Requires the Segment Polarity Gene wingless

1995 • 221 citations

TheXenopusGATA-4/5/6 Genes Are Associated with Cardiac Specification and Can Regulate Cardiac-Specific Transcription during Embryogenesis

1996 • 202 citations

The Wingless Signaling Pathway Is Directly Involved inDrosophilaHeart Development

1996 • 193 citations

Mesodermal subdivision along the mediolateral axis in chicken controlled by different concentrations of BMP-4

1997 • 183 citations

Heart development in Drosophila and its relationship to vertebrates

1995 • 173 citations

MASH1 maintains competence for BMP2-induced neuronal differentiation in post-migratory neural crest cells

1997 • 166 citations

Mesoderm Induction by BMP-4 and -7 Heterodimers

1997 • 147 citations

Anterior endoderm is a specific effector of terminal cardiac myocyte differentiation of cells from the embryonic heart forming region

1994 • 145 citations

Regulation ofparaxisExpression and Somite Formation by Ectoderm- and Neural Tube-Derived Signals

1997 • 142 citations

Induction of cardiac myogenesis in avian pregastrula epiblast: the role of the hypoblast and activin

1997 • 134 citations

Migration patterns of the precardiac mesoderm in the early chick embryo

1963 • 132 citations

Activation of Fgf-4 and HoxD gene expression by BMP-2 expressing cells in the developing chick limb

1996 • 130 citations

The specification of heart mesoderm occurs during gastrulation in Xenopus laevis

1989 • 125 citations

Location and movements of cardiogenic cells in the chick embryo: The heart-forming portion of the primitive streak

1970 • 122 citations

Activin and Its Receptors during Gastrulation and the Later Phases of Mesoderm Development in the Chick Embryo

1995 • 117 citations

Wnt-11 is expressed in early avian mesoderm and required for the differentiation of the quail mesoderm cell line QCE-6

1997 • 109 citations

Identification and characterization of a ventricular-specific avian myosin heavy chain, VMHC1: Expression in differentiating cardiac and skeletal muscle

1991 • 107 citations

The role of the dorsal lip in the induction of heart mesoderm in Xenopus laevis

1990 • 106 citations

Precardiac mesoderm is specified during gastrulation in quail

1994 • 104 citations

Short-Range Signaling by Candidate Morphogens of the TGFβ Family and Evidence for a Relay Mechanism of Induction

1996 • 104 citations

Bone morphogenetic protein 2 in the early development of Xenopus laevis

1995 • 103 citations

Cardiac Troponin I Is a Heart-Specific Marker in the Xenopus Embryo: Expression during Abnormal Heart Morphogenesis

1994 • 102 citations

In vitro analysis of cardiac progenitor cell differentiation

1990 • 102 citations

Initiation of cardiac differentiation occurs in the absence of anterior endoderm

1995 • 101 citations

Induction of cardiac muscle differentiation in isolated animal pole explants of Xenopus laevis embryos

1993 • 96 citations

Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeo☐ gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development

1996 • 81 citations

Staging of Commitment and Differentiation of Avian Cardiac Myocytes

1994 • 67 citations

Well-defined growth factors promote cardiac development in axolotl mesodermal explants

1991 • 65 citations

Onset of expression and regional deposition of alpha‐smooth and sarcomeric actin during avian heart development

1992 • 59 citations

Chicken NKx2–8, a novel homeobox gene expressed during early heart and foregut development

1997 • 55 citations

Transforming Growth Factor-β Signal Transduction

1996 • 38 citations

Endoderm and Cardiogenesis

1996 • 37 citations

Hypoblastic tissue and fibroblast growth factor induce blood tissue (haemoglobin) in the early chick embryo

1994 • 31 citations

Some observations on the growth and function of heteroplastic heart grafts

1939 • 19 citations