Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis.

Bone: Formation by Autoinduction

1965 • 5,498 citations

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms.

1994 • 1,950 citations

Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

1995 • 1,782 citations

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

1988 • 1,690 citations

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

1990 • 1,531 citations

Expression cloning of the TGF-β type II receptor, a functional transmembrane serine/threonine kinase

1992 • 1,071 citations

Teratocarcinomas and embryonic stem cells : a practical approach

1987 • 878 citations

Requirement for LIml in head-organizer function

1995 • 801 citations

Cloning of a TGF$beta; type I receptor that forms a heteromeric complex with the TGF$beta; type II receptor

1993 • 779 citations

A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

1994 • 769 citations

Expression cloning of an activin receptor, a predicted transmembrane serine kinase

1991 • 760 citations

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.

1994 • 737 citations

The bone morphogenetic protein family and osteogenesis

1992 • 686 citations

Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo

1993 • 680 citations

Identification of human activin and TGFβ type I receptors that form heteromeric kinase complexes with type II receptors

1993 • 656 citations

Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

1991 • 646 citations

Different phenotypes for mice deficient in either activins or activin receptor type II

1995 • 598 citations

Dissociative extraction and reconstitution of extracellular matrix components involved in local bone differentiation.

1981 • 585 citations

Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development

1992 • 573 citations

Disruption of the HNF-4 gene, expressed in visceral endoderm, leads to cell death in embryonic ectoderm and impaired gastrulation of mouse embryos.

1994 • 550 citations

Novel activin receptors: Distinct genes and alternative mRNA splicing generate a repertoire of serine/threonine kinase receptors

1992 • 495 citations

Maternal Rescue of Transforming Growth Factor-β 1 Null Mice

1994 • 494 citations

DVR-4 (Bone Morphogenetic Protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction

1992 • 488 citations

The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFβ superfamily

1992 • 483 citations

Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo

1992 • 467 citations

Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb

1994 • 465 citations

Evidence for Involvement of Activin A and Bone Morphogenetic Protein 4 in Mammalian Mesoderm and Hematopoietic Development

1995 • 464 citations

Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo

1994 • 463 citations

A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo.

1994 • 449 citations

Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development.

1989 • 440 citations

Cloning of a Type I TGF-β Receptor and Its Effect on TGF-β Binding to the Type II Receptor

1993 • 401 citations

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

1994 • 396 citations

Bone and cartilage differentiation

1994 • 389 citations

Gastrulation in the mouse: The role of the homeobox gene goosecoid

1992 • 378 citations

Characterization and Cloning of a Receptor for BMP-2 and BMP-4 from NIH 3T3 Cells

1994 • 368 citations

The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans dauer larva development

1993 • 368 citations

Activin receptor-like kinases: a novel subclass of cell-surface receptors with predicted serine/threonine kinase activity.

1993 • 354 citations

Expression pattern of the Brachyury gene in whole-mount T WIS/T WIS mutant embryos

1991 • 350 citations

Gastrulation in the mouse : Growth and regionalization of the epiblast

1977 • 340 citations

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

1995 • 326 citations

Characterization and relationship of dpp receptors encoded by the saxophone and thick veins genes in Drosophila

1994 • 317 citations

An absolute requirement for both the type II and type I receptors, punt and thick veins, for Dpp signaling in vivo

1995 • 312 citations

What do BMPs do in mammals? Clues from the mouse short-ear mutation

1994 • 300 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

Cloning, expression, and alternative splicing of the receptor for anti-Müllerian hormone.

1994 • 279 citations

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family

1995 • 275 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor

1994 • 254 citations

The control of cell fate along the dorsal-ventral axis of the Drosophila embryo

1991 • 246 citations

Embryonic Expression of Lim-1, the Mouse Homolog of Xenopus XLim-1, Suggests a Role in Lateral Mesoderm Differentiation and Neurogenesis

1994 • 215 citations

A pheromone-induced developmental switch in Caenorhabditis elegans: Temperature-sensitive mutants reveal a wild-type temperature-dependent process.

1984 • 210 citations

The screw gene encodes a ubiquitously expressed member of the TGF-beta family required for specification of dorsal cell fates in the Drosophila embryo.

1994 • 199 citations

Production and analysis of chimeric mice

1987 • 175 citations

A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm.

1994 • 162 citations

The Drosophila saxophone Gene: a Serine-Threonine Kinase Receptor of the TGF-β Superfamily

1994 • 131 citations

[10] Isolation and culture of whole postimplantation embryos and germ layer derivatives

1993 • 111 citations

Effects of fixation time and enzymatic digestion on immunohistochemical demonstration of bromodeoxyuridine in formalin-fixed, paraffin-embedded tissue.

1988 • 108 citations

Cloning, expression, and alternative splicing of the receptor for anti- Mullerian hormone

1994 • 103 citations

Onset of gastrulation, morphogenesis and somitogenesis in mouse embryos displaying compensatory growth

1993 • 97 citations

Cartilage homeoprotein 1, a homeoprotein selectively expressed in chondrocytes.

1993 • 89 citations

A Mammalian Serine/Threonine Kinase Receptor Specifically Binds BMP-2 and BMP-4

1994 • 86 citations

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis

1995 • 70 citations

msd is required for mesoderm induction in mice

1994 • 39 citations

Genomic Organization and Chromosomal Location of the Mouse Type I BMP-2/4 Receptor

1995 • 27 citations

Morphological stages of postimplantation Embryonic development

1990 • 22 citations

Cloning of a Drosophila melanogaster homologue of the mouse type-I bone morphogenetic proteins-2/-4 receptor: a potential decapentaplegic receptor

1994 • 17 citations

[11] Histogenetic potency of embryonic tissues in ectopic sites

1993 • 10 citations