Chick NKx-2.3 represents a novel family member of vertebrate homologues to the Drosophila homeo☐ gene tinman: differential expression of cNKx-2.3 and cNKx-2.5 during heart and gut development

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

A series of normal stages in the development of the chick embryo

1951 • 12,226 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.

1995 • 1,130 citations

A tissue-specific transcription factor containing a homeodomain specifies a pituitary phenotype

1988 • 998 citations

The gene tinman is required for specification of the heart and visceral muscles in Drosophila

1993 • 790 citations

tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila.

1993 • 719 citations

Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart.

1993 • 708 citations

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

1994 • 553 citations

Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.

1990 • 545 citations

Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut

1995 • 531 citations

Requirement of MADS Domain Transcription Factor D-MEF2 for Muscle Formation in Drosophila

1995 • 502 citations

Pax-3 is required for the development of limb muscles: a possible role for the migration of dermomyotomal muscle progenitor cells

1994 • 495 citations

Induction of avian cardiac myogenesis by anterior endoderm

1995 • 475 citations

Drosophila MEF2, a transcription factor that is essential for myogenesis.

1995 • 426 citations

Variations of cervical vertebrate after expression of a Hox-1.1 transgene in mice

1990 • 371 citations

Homeosis in the mouse induced by a null mutation in the Hox-3.1 gene

1992 • 364 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development

1994 • 299 citations

Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain

1992 • 291 citations

Identification of Novel DNA Binding Targets and Regulatory Domains of a Murine Tinman Homeodomain Factor, nkx-2.5

1995 • 289 citations

GATA-4 is a novel transcription factor expressed in endocardium of the developing heart

1993 • 250 citations

A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila

1990 • 237 citations

hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors.

1993 • 234 citations

Human Hox-4.2 and Drosophila Deformed encode similar regulatory specificities in Drosophila embryos and larvae

1990 • 225 citations

XNkx-2.5, a Xenopus Gene Related to Nkx-2.5 and tinman: Evidence for a Conserved Role in Cardiac Development

1994 • 219 citations

HNF1, a homeoprotein member of the hepatic transcription regulatory network

1992 • 210 citations

The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle

1994 • 200 citations

Origin and differentiation of cardiac muscle cells in the mouse

1973 • 186 citations

Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae

1990 • 182 citations

The development of the myocardium and endocardium in mouse embryos

1992 • 179 citations

Heart development in Drosophila and its relationship to vertebrates

1995 • 173 citations

Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene

1992 • 160 citations

Expression of bone morphogenetic protein-4 (BMP-4), bone morphogenetic protein-7 (BMP-7), fibroblast growth factor-8 (FGF-8) and sonic hedgehog (SHH) during branchial arch development in the chick

1995 • 151 citations

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

1991 • 133 citations

tinman, a Drosophila homeobox gene required for heart and visceral mesoderm specification, may be represented by a family of genes in vertebrates: XNkx-2.3, a second vertebrate homologue of tinman

1995 • 126 citations

Altering the boundaries of Hox3.1 expression: Evidence for antipodal gene regulation

1992 • 125 citations

A human HOX4B regulatory element provides head-specific expression in Drosophila embryos

1992 • 100 citations

The RSRF/MEF2 protein SL1 regulates cardiac muscle-specific transcription of a myosin light-chain gene in Xenopus embryos.

1994 • 94 citations

Intimations of a creature

1994 • 92 citations

Deformed autoregulatory element from Drosophila functions in a conserved manner in transgenic mice

1992 • 71 citations

Axial patterning and the establishment of polarity in the frog embryo

1990 • 63 citations

The myogenin gene is activated during myocyte differentiation by pre-existing, not newly synthesized transcription factor MEF-2.

1994 • 63 citations

Morphogenesis of the Vertebrate Heart

2007 • 44 citations