Acute pain and pain control: State of the art

Gender variations in clinical pain experience

1996 • 1,525 citations

Addiction Is a Brain Disease, and It Matters

1997 • 1,486 citations

Gabapentin for the Treatment of Postherpetic Neuralgia<SUBTITLE>A Randomized Controlled Trial</SUBTITLE>

1998 • 1,461 citations

COX-2 inhibitors

1999 • 1,177 citations

Ethnicity as a Risk Factor for Inadequate Emergency Department Analgesia

1993 • 845 citations

Opioid pseudoaddiction — an iatrogenic syndrome

1989 • 629 citations

Does the Clinically Significant Difference in Visual Analog Scale Pain Scores Vary with Gender, Age, or Cause of Pain?

1998 • 580 citations

Phantom limb pain in amputees during the first 12 months following limb amputation, after preoperative lumbar epidural blockade

1988 • 570 citations

Lidocaine patch: double-blind controlled study of a new treatment method for post-herpetic neuralgia

1996 • 543 citations

Opioid therapy for chronic nonmalignant pain: a review of the critical issues

1996 • 524 citations

Mapping of punctuate hyperalgesia around a surgical incision demonstrates that ketamine is a powerful suppressor of central sensitization to pain following surgery

1997 • 519 citations

Relief of post-herpetic neuralgia with the Symbol receptor antagonist ketamine: A double-blind, cross-over comparison with morphine and placebo

1994 • 483 citations

Transdermal fentanyl versussustained-release oral morphine in cancer pain: Preference, efficacy, and quality of life

1997 • 478 citations

Oligoanalgesia in the emergency department

1989 • 467 citations

Consequences of Inadequate Analgesia During Painful Procedures in Children

1998 • 458 citations

Analgesia and Sedation in Preterm Neonates Who Require Ventilatory Support

1999 • 425 citations

The Symbol receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man

1994 • 368 citations

High‐dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia

1997 • 357 citations

On the relation of injury to pain the John J. Bonica Lecture

1979 • 346 citations

Treatment of Acute Migraine With Subcutaneous Sumatriptan

1991 • 313 citations

Viscosupplementation with Hylan G-F 20: A 26-week controlled trial of efficacy and safety in the osteoarthritic knee

1998 • 297 citations

Viscosupplementation with hylan for the treatment of osteoarthritis: findings from clinical practice in Canada.

1996 • 297 citations

Mechanisms of touch-evoked pain (allodynia): a new model

1996 • 283 citations

Mid-clavicle Fractures in Adults: End Result Study After Conservative Treatment

1998 • 280 citations

Screening for Addiction in Patients with Chronic Pain and “Problematic” Substance Use

1998 • 269 citations

The effects of pre-emptive treatment ofpostherpetic neuralgia with amitriptyline: A randomized, double-blind, placebo-controlled trial

1997 • 268 citations

The Minimum Clinically Important Difference in Physician–assigned Visual Analog Pain Scores

1996 • 268 citations

Continuous subcutaneous administration of the N -methyl-D-aspartic acid (NMDA) receptor antagonist ketamine in the treatment of post-herpetic neuralgia

1995 • 263 citations

Does Gender Affect Appraisal of Pain and Pain Coping Strategies?

1999 • 242 citations

Comparison of patient and practitioner assessments of pain from commonly performed emergency department procedures

1999 • 241 citations

Treatment of clavicular fractures: Figure-of-elght bandage versus a slmple sling

1987 • 230 citations

Quality of life and cancer pain: satisfaction and side effects with transdermal fentanyl versus oral morphine.

1998 • 228 citations

Analgesic Drug Prescription and Use in Cognitively Impaired Nursing Home Residents

1998 • 227 citations

Randomized, Placebo-Controlled Evaluation of Prochlorperazine Versus Metoclopramide for Emergency Department Treatment of Migraine Headache

1995 • 223 citations

Safety of early pain relief for acute abdominal pain.

1992 • 215 citations

The Effect of Ethnicity on Physician Estimates of Pain Severity in Patients with Isolated Extremity Trauma

1994 • 203 citations

Paracetamol with and without codeine in acute pain: a quantitative systematic review

1997 • 196 citations

An intrusive impact of anchors in children's faces pain scales

1998 • 196 citations

Age as a risk factor for inadequate emergency department analgesia

1996 • 185 citations

Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design

1994 • 185 citations

Clinical Versus Statistical Significance in the Assessment of Pain Relief☆☆☆★

1996 • 184 citations

Analgesic effect of Salmon calcitonin in osteoporotic vertebral fractures: A double-blind placebo-controlled clinical study

1991 • 177 citations

Intravenous Morphine for Early Pain Relief in Patients with Acute Abdominal Pain

1996 • 176 citations

Chronic opioid therapy for nonmalignant pain in patients with a history of substance abuse: Report of 20 cases

1996 • 169 citations

Are Emergency Physicians Too Stingy With Analgesics?

1994 • 169 citations

Prospective, Randomized Comparison of Epidural Versus Parenteral Opioid Analgesia in Thoracic Trauma

1999 • 168 citations

Reassessment of verbal and visual analog ratings in analgesic studies

1985 • 166 citations

Discussion

1998 • 165 citations

Blockade of peripheral neuronal barrage reduces postoperative pain

1997 • 157 citations

Prolonged Intercostal Nerve Blockade in Sheep Using Controlled-release of Bupivacaine and Dexamethasone from Polymer Microspheres

1998 • 152 citations

Prolonged Treatment with Transdermal Fentanyl in Neuropathic Pain

1998 • 147 citations

Pain: The Science of Suffering

2000 • 142 citations

Analgesic efficacy and safety of paracetamol-codeine combinations versus paracetamol alone: a systematic review

1996 • 140 citations

Gender-Associated Differences in Emergency Department Pain Management

1995 • 140 citations

Pain relief from nasal salmon calcitonin in osteoporotic vertebral crush fractures

1997 • 138 citations

Pain Measurement in Persons with Intellectual Disabilities

1999 • 133 citations

Pain—the Science of Suffering

1999 • 133 citations

Local treatment with the N-methyl-d-aspartate receptor antagonist ketamine, inhibit development of secondary hyperalgesia in man by a peripheral action

1997 • 131 citations

Postherpetic Neuralgia: Impact of Famciclovir, Age, Rash Severity, and Acute Pain in Herpes Zoster Patients

1998 • 130 citations

One-Week Survey of Pain Intensity on Admission to and Discharge from the Emergency Department: A Pilot Study

1998 • 128 citations

A prospective blinded study on emergency pain assessment and therapy

1995 • 126 citations

Venipuncture Is More Effective and Less Painful Than Heel Lancing for Blood Tests in Neonates

1998 • 125 citations

The use of analgesics in patients with acute abdominal pain

1997 • 121 citations

Femoral nerve block in extracapsular femoral neck fractures

1995 • 112 citations

Analgesia in the acute abdomen.

1986 • 108 citations

Acute Appendicitis: Influence of Early Pain Relief on the Accuracy of Clinical and US Findings in the Decision to Operate—A Randomized Trial

1999 • 107 citations

Subcutaneous Sumatriptan for Treatment of Acute Migraine in Patients Admitted to the Emergency Department: A Multicenter Study

1995 • 105 citations

Nitrous Oxide—Oxygen Sedation for Minor Surgery

1981 • 103 citations

Nitrous oxide analgesia in a pediatric emergency department

1990 • 102 citations

Comparison of Intravenous Ketorolac, Meperidine, and Both (Balanced Analgesia) for Renal Colic

1996 • 94 citations

Transdermal fentanyl in children with cancer pain: Feasibility, tolerability, and pharmacokinetic correlates

1999 • 93 citations

A randomized, controlled trial of the use of music during laceration repair

1991 • 92 citations

Transdermal fentanyl as treatment for chronic low back pain

1997 • 91 citations

Topical lidocaine reduces pain in post-herpetic neuralgia

1989 • 84 citations

Emergency pain management: A Canadian Association of emergency Physicians (CAEP) consensus document

1994 • 82 citations

Psychological Barriers to Optimal Pain Management in Infants and Children

1996 • 75 citations

Pain Management and Chemical Dependency

1997 • 70 citations

Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy

1998 • 66 citations

Ineffectiveness of Dextromethorphan in Cancer Pain

1998 • 65 citations

Preoperative Dextromethorphan Reduces Intraoperative but Not Postoperative Morphine Requirements After Laparotomy

1998 • 63 citations

Building blocks of pain: the regulation of key molecules in spinal sensory neurones during development and following peripheral axotomy

1999 • 62 citations

Preoperative Oral Dextromethorphan Does Not Reduce Pain or Analgesic Consumption in Children After Adenotonsillectomy

1999 • 59 citations

A protocol to improve analgesia use in the accident and emergency department.

1996 • 59 citations

Early Ankle Mobilization, Part I: The Immediate Effect on Acute, Lateral Ankle Sprains (A Randomized Clinical Trial)

1994 • 59 citations

Music Does Not Reduce Alfentanil Requirement During Patient-Controlled Analgesia (PCA) Use in Extracorporeal Shock Wave Lithotripsy for Renal Stones

1998 • 58 citations

A Controlled Clinical Trial of Local Anesthesia for Lumbar Punctures in Newborns

1991 • 57 citations

Comparison of patient-controlled sedation with either methohexitone or propofol

1996 • 56 citations

Emergency Management of Migraine: Is the Headache Really Over?

1998 • 56 citations

Preincisional Dextromethorphan Treatment Decreases Postoperative Pain and Opioid Requirement After Laparoscopic Cholecystectomy

1999 • 56 citations

Indomethacin Suppositories Versus Intravenously Titrated Morphine for the Treatment of Ureteral Colic

1994 • 56 citations

Mechanisms of Central Hypersensitivity: Excitatory Amino Acid Mechanisms and Their Control

1997 • 55 citations

Analgesic Practice for Acute Orthopedic Trauma Pain in Costa Rican Emergency Departments

1996 • 53 citations

An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist

1995 • 52 citations

Viscosupplementation: A new concept in the treatment of sacroiliac joint syndrome: A preliminary report of four cases

1999 • 51 citations

Comparison of Topical Anesthetics and Vasoconstrictors vs Lubricants Prior to Nasogastric Intubation: A Randomized, Controlled Trial

1999 • 49 citations

Pain and Fear Ratings

1998 • 49 citations

In Search of a New Ethic for Treating Patients with Chronic Pain: What Can Medical Boards Do?

1998 • 47 citations

Intradermal normal saline solution, self-selected music, and insertion difficulty effects on intravenous insertion pain

1999 • 47 citations

Preincisional Dextromethorphan Treatment Decreases Postoperative Pain and Opioid Requirement After Laparoscopic Cholecystectomy

1999 • 47 citations

Ketamine Infusion for Postoperative Analgesia in Asthmatics

1993 • 47 citations

Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy

1998 • 46 citations

Nsaid Use and Efficacy in the Emergency Department: Single Doses of Oral Ibuprofen versus Intramuscular Ketorolac

1994 • 46 citations

Canadian Pain Society Position Statement on Pain Relief

1999 • 43 citations

The medical and surgical management of trigeminal neuralgia

1995 • 42 citations

Acute herpes zoster and postherpetic neuralgia: effects of acyclovir and outcome of treatment with amitriptyline.

1992 • 41 citations

Intravenous ondansetron for the control of opioid-induced nausea and vomiting

1999 • 40 citations

A study of pain management: patient controlled analgesia versus intramuscular analgesia.

1989 • 40 citations

Postoperative use of pediatric pain scales: children's self-report versus nurse assessment of pain intensity and affect

1996 • 37 citations

Effects of dextromethorphan in clinical doses on capsaicin-induced ongoing pain and mechanical hypersensitivity

1997 • 35 citations

Preoperative Oral Dextromethorphan Does Not Reduce Pain or Analgesic Consumption in Children After Adenotonsillectomy

1999 • 34 citations

Preoperative traction for hip fractures in the elderly: a clinical trial

1993 • 31 citations

Pain and its control in patients with fractures of the femoral neck while awaiting surgery

1994 • 28 citations

Parental perception of the adequacy of pain control in their child after discharge from the emergency department

1998 • 27 citations

Patient empowerment and feedback did not decrease pain in seriously ill hospitalized adults

1998 • 27 citations

Safety of a nurse‐managed, titrated analgesia protocol for the management of severe pain in the emergency department

1999 • 25 citations

Do patients receive adequate pain control after discharge from the ED?

1998 • 24 citations

Trauma Management: An Emergency Medicine Approach

2001 • 22 citations

From electrical wiring to plastic neurons: evolving approaches to the study of pain

1999 • 19 citations

Oral indomethacin for acute renal colic

1991 • 19 citations

Pharmacology of Pain and Analgesia

1980 • 18 citations

A new approach to chronic pain in the ED

1996 • 18 citations

Studying Emergency Patients Outside the Emergency Department☆☆☆★

1996 • 14 citations

Practical implications of cyclooxygenase-2--specific inhibitors in orthopedics.

1999 • 13 citations

Management of blunt chest injury.

1996 • 11 citations

Preference for Comfort Care Does Not Affect the Pain Experience of Seriously Ill Patients

1998 • 11 citations

Clinical applications of hypnotherapy.

1990 • 10 citations

Pharmacology of pain and analgesia

1981 • 2 citations