Preincisional Dextromethorphan Treatment Decreases Postoperative Pain and Opioid Requirement After Laparoscopic Cholecystectomy

Preemptive Analgesia—Treating Postoperative Pain by Preventing the Establishment of Central Sensitization

1993 • 1,661 citations

Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following c fibre stimulation.

1987 • 836 citations

Evidence for involvement ofN-methylaspartate receptors in ‘wind-up’ of class 2 neurones in the dorsal horn of the rat

1987 • 666 citations

RECENT ADVANCES IN THE PATHOPHYSIOLOGY OF ACUTE PAIN

1989 • 389 citations

The Symbol receptor antagonist dextromethorphan selectively reduces temporal summation of second pain in man

1994 • 368 citations

High‐dose oral dextromethorphan versus placebo in painful diabetic neuropathy and postherpetic neuralgia

1997 • 357 citations

METABOLIC AND RESPIRATORY CHANGES AFTER CHOLECYSTECTOMY PERFORMED VIA LAPAROTOMY OR LAPAROSCOPY

1992 • 352 citations

A cure for wind up: NMDA receptor antagonists as potential analgesics

1990 • 327 citations

Differential effects of excitatory amino acid antagonists on dorsal horn nociceptive neurones in the rat

1990 • 310 citations

Pain After Laparoscopic Cholecystectomy

1995 • 299 citations

Dextromethorphan An Overview of Safety Issues

1992 • 221 citations

Dextromethorphan for the treatment of neuropathic pain: a double-blind randomised controlled crossover trial with integral n-of-1 design

1994 • 185 citations

Dextrorphan relieves neuropathic heat-evoked hyperalgesia in the rat

1993 • 151 citations

Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons

1993 • 140 citations

Residual pneumoperitoneum: a cause of postoperative pain after laparoscopic cholecystectomy.

1994 • 140 citations

Effect of systemic N-methyl-D-aspartate receptor antagonist (dextromethorphan) on primary and secondary hyperalgesia in humans

1997 • 139 citations

Pre-emptive analgesia with ketamine, morphine and epidural lidocaine prior to total knee replacement

1997 • 86 citations

Effects of Ketorolac on Postoperative Analgesia and Ventilatory Function After Laparoscopic Cholecystectomy

1993 • 85 citations

Dextromethorphan suppresses both formalin-induced nociceptive behavior and the formalin-induced increase in spinal cord c- fos mRNA

1995 • 75 citations

Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy

1998 • 66 citations

Preoperative Dextromethorphan Reduces Intraoperative but Not Postoperative Morphine Requirements After Laparotomy

1998 • 63 citations

Dextromethorphan and pain after total abdominal hysterectomy

1998 • 53 citations

An attempt to attenuate experimental pain in humans by dextromethorphan, an NMDA receptor antagonist

1995 • 52 citations

Premedication with Oral Dextromethorphan Reduces Postoperative Pain After Tonsillectomy

1998 • 46 citations

The estimation of solubility in binary solvents: application of the reduced 3-suffix solubility equation to ethanol-water mixtures.

1988 • 32 citations