A public health perspective

Disease control priorities in developing countries

2006 • 3,882 citations

The Epidemiologic Transition: A Theory of the Epidemiology of Population Change

2005 • 3,730 citations

Sudden Cardiac Death

1998 • 2,640 citations

A review of harmful algal blooms and their apparent global increase

1993 • 2,362 citations

World development report 1993 : investing in health

1993 • 2,311 citations

Thrombosis and Acute Coronary-Artery Lesions in Sudden Cardiac Ischemic Death

1984 • 1,700 citations

Sudden Cardiac Death in the United States, 1989 to 1998

2001 • 1,583 citations

Sudden Death Due to Cardiac Arrhythmias

2001 • 1,439 citations

Triggering of Acute Myocardial Infarction by Heavy Physical Exertion -- Protection against Triggering by Regular Exertion

1993 • 1,414 citations

Cardiopulmonary resuscitation of adults in the hospital: A report of 14 720 cardiac arrests from the National Registry of Cardiopulmonary Resuscitation

2003 • 1,232 citations

Contact force measurements and stress-induced anisotropy in granular materials

2005 • 1,115 citations

First Documented Rhythm and Clinical Outcome From In-Hospital Cardiac Arrest Among Children and Adults

2006 • 1,103 citations

Moderate Alcohol Intake, Increased Levels of High-Density Lipoprotein and Its Subfractions, and Decreased Risk of Myocardial Infarction

1993 • 1,044 citations

Drug induced QT prolongation and torsades de pointes

2003 • 918 citations

Immediate Coronary Angiography in Survivors of Out-of-Hospital Cardiac Arrest

1997 • 914 citations

The Fourth Stage of the Epidemiologic Transition: The Age of Delayed Degenerative Diseases

1986 • 797 citations

Current burden of sudden cardiac death: Multiple source surveillance versus retrospective death certificate-based review in a large U.S. community

2004 • 755 citations

Predicting Sudden Death in the Population

1999 • 624 citations

Reliability, validity, and classification accuracy of the South Oaks Gambling Screen (SOGS)

2002 • 564 citations

Effect of alcohol consumption on systemic markers of inflammation

2001 • 558 citations

Poisonous and venomous marine animals of the world

1988 • 558 citations

Gambling and the Health of the Public: Adopting a Public Health Perspective

1999 • 531 citations

Gambling and Related Mental Disorders: A Public Health Analysis

2002 • 530 citations

Adolescent Gambling Behavior: A Prevalence Study and Examination of the Correlates Associated with Problem Gambling

1998 • 486 citations

Population-Based Analysis of Sudden Cardiac Death With and Without Left Ventricular Systolic Dysfunction

2006 • 477 citations

Structures and configurations of ciguatoxin from the moray eel Gymnothorax javanicus and its likely precursor from the dinoflagellate Gambierdiscus toxicus

1990 • 466 citations

The Burden of Disease and Mortality by Condition: Data, Methods, and Results for 2001

2006 • 463 citations

Incidence of EMS-treated out-of-hospital cardiac arrest in the United States

2004 • 461 citations

What makes women sick: gender and the political economy of health

1995 • 432 citations

Ciguatera: recent advances but the risk remains

2000 • 423 citations

Report of a WHO workshop on the standardization and control of antivenoms

2003 • 421 citations

Internet Gambling: Issues, Concerns, and Recommendations

2003 • 405 citations

The Association between Hospital Volume and Survival after Acute Myocardial Infarction in Elderly Patients

1999 • 381 citations

Relationship of Hospital Teaching Status With Quality of Care and Mortality for Medicare Patients With Acute MI

2000 • 343 citations

Finding of a dinoflagellate as a likely culprit of ciguatera.

1977 • 336 citations

Out-of-hospital cardiac arrest-the relevance of heart failure. The Maastricht Circulatory Arrest Registry

2003 • 326 citations

A cumulative meta-analysis of the effectiveness of defibrillator-capable emergency medical services for victims of out-of-hospital cardiac arrest

1999 • 315 citations

Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes.

1986 • 313 citations

Structures of ciguatoxin and its congener

1989 • 310 citations

Ciguatoxin and brevetoxins share a common receptor site on the neuronal voltage‐dependent Na⁺ channel

1987 • 304 citations

Purification and characterization of ciguatoxins from moray eel (Lycodontis javanicus, Muraenidae)

1991 • 293 citations

Ciguatoxin: Isolation and Chemical Nature

1967 • 286 citations

Diabetes, glucose level, and risk of sudden cardiac death

2005 • 252 citations

The Thecal Structure of a Marine Toxic Dinoflagellate Gambierdiscus toxicus gen. et sp. nov. Collected in a Ciguatera-endemic Area

1979 • 246 citations

Ciguatoxin is a novel type of Na+ channel toxin.

1984 • 245 citations

IMPACT OF SNAKE BITES AND DETERMINANTS OF FATAL OUTCOMES IN SOUTHEASTERN NEPAL

2004 • 234 citations

Detection of Sodium Channel Toxins: Directed Cytotoxicity Assays of Purified Ciguatoxins, Brevetoxins, Saxitoxins, and Seafood Extracts

1995 • 234 citations

Prediction, prevention, and mechanism of early (anaphylactic) antivenom reactions in victims of snake bites.

1986 • 232 citations

Ciguatera in Australia: Occurrence, clinical features, pathophysiology and management

1986 • 221 citations

Origin and transfer of toxins involved in ciguatera

1993 • 220 citations

Neurology of ciguatera

2001 • 219 citations

Dynamics of a Projectile Penetrating Sand

1957 • 215 citations

Acute Psychological Disturbances Preceding Life-Threatening Ventricular Arrhythmias

1981 • 212 citations

Origins of ciguatera fish poisoning: a new dinoflagellate, Gambierdiscus toxicus Adachi and Fukuyo, definitively involved as a causal agent

1980 • 212 citations

Structure and pharmacology of elapid cytotoxins

1988 • 208 citations

Pharmacokinetic-Pharmacodynamic Relationships of Immunoglobulin Therapy for Envenomation

2003 • 200 citations

Factors associated with survival to hospital discharge among patients hospitalised alive after out of hospital cardiac arrest: change in outcome over 20 years in the community of Goteborg, Sweden

2002 • 194 citations

Population Policy and Women's Rights: Transforming Reproductive Choice.

1994 • 194 citations

OBSERVATION OF SAND‐DWELLING TOXIC DINOFLAGELLATES (DINOPHYCEAE) FROM WIDELY DIFFERING SITES, INCLUDING TWO NEW SPECIES

1995 • 192 citations

Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom

1998 • 190 citations

Physical Exertion, Exercise, and Sudden Cardiac Death in Women

2006 • 185 citations

Foodborne Disease Handbook

2000 • 183 citations

Incidence of Out-of-Hospital cardiac arrest

2004 • 182 citations

Successful Treatment of Ciguatera Fish Poisoning With Intravenous Mannitol

1988 • 180 citations

Structural Elucidation of Ciguatoxin Congeners by Fast-Atom Bombardment Tandem Mass Spectroscopy

2000 • 177 citations

Monitoring adolescent gambling in Minnesota

1995 • 166 citations

Effectiveness of Emergency Medical Services for Victims of Out-of-Hospital Cardiac Arrest: A Metaanalysis

1996 • 161 citations

Ciguatera fish poisoning

2002 • 156 citations

Identification of peptide components of the brevetoxin receptor site of rat brain sodium channels.

1994 • 148 citations

Isolation and characterisation of Caribbean ciguatoxins from the horse-eye jack (Caranx latus)

1997 • 147 citations

Disordered gambling among university-based medical and dental patients: A focus on Internet gambling.

2002 • 146 citations

Ciguatera Fish Poisoning

1982 • 146 citations

Using Admission Characteristics to Predict Short-term Mortality From Myocardial Infarction in Elderly Patients

1996 • 145 citations

Ciguatera: Australian perspectives on a global problem

2006 • 145 citations

Ciguatera Fish Poisoning in Miami

1980 • 143 citations

Primary production and the global epidemic of phytoplankton blooms in the sea: A linkage?

1989 • 143 citations

Quality of Care for Acute Myocardial Infarction in Rural and Urban US Hospitals

2004 • 142 citations

Strain dependent production of ciguatoxin precursors (gambiertoxins) by Gambierdiscus toxicus (Dinophyceae) in culture

1991 • 142 citations

Granular drag on a discrete object: Shape effects on jamming

2001 • 142 citations

Isolation and structures of new ciguatoxin analogs, 2,3-dihydroxyCTX3C and 51-hydroxyCTX3C, accumulated in tropical reef fish

1998 • 137 citations

Creating a dry variety of quicksand

2004 • 130 citations

Ciguatoxins: Cyclic Polyether Modulators of Voltage-gated Iion Channel Function

2006 • 129 citations

Harmful algal bloom causative collected from Hong Kong waters

2004 • 127 citations

Toxicity of the surgeonfishes. II. Properties of the principal water-soluble toxin.

1976 • 124 citations

Isolation and Structure of Ciguatoxin-4A, a New Ciguatoxin Precursor, from Cultures of DinoflagellateGambierdiscus toxicusand ParrotfishScarus gibbus

1996 • 121 citations

Effects of Statin Therapy on Arrhythmic Events and Survival in Patients With Nonischemic Dilated Cardiomyopathy

2006 • 120 citations

Seawater temperature, Gambierdiscus spp. variability and incidence of ciguatera poisoning in French Polynesia

2005 • 117 citations

Ciguatera in Réunion Island (SW Indian Ocean): Epidemiology and clinical patterns

1996 • 113 citations

High incidence of bites and stings by snakes and other animals among rubber tappers and amazonian indians of the Juruá Valley, Acre State, Brazil

1996 • 109 citations

Nodal swelling produced by ciguatoxin-induced selective activation of sodium channels in myelinated nerve fibers

1996 • 109 citations

GAMBIERDISCUS YASUMOTOI SP. NOV. (DINOPHYCEAE), A TOXIC BENTHIC DINOFLAGELLATE FROM SOUTHEASTERN ASIA

1998 • 107 citations

HPLC/Tandem Electrospray Mass Spectrometry for the Determination of Sub-ppb Levels of Pacific and Caribbean Ciguatoxins in Crude Extracts of Fish

1998 • 106 citations

Seasonal abundance and toxicity of the dinoflagellate Gambierdiscus spp. (Dinophyceae), the causative agent of ciguatera in Tahiti, French Polynesia

1999 • 105 citations

Ciguatera and mannitol: experience with a new treatment regimen

1989 • 105 citations

Use of two detection methods to discriminate ciguatoxins from brevetoxins: Application to great barracuda from Florida Keys

2005 • 104 citations

Effects of ciguatoxin on current and voltage clamped frog myelinated nerve fibre

1986 • 103 citations

Regional variation in the treatment and outcomes of myocardial infarction: investigating New England’s advantage

2003 • 102 citations

Monitoring brevetoxins during a Gymnodinium breve red tide: comparison of sodium channel specific cytotoxicity assay and mouse bioassay for determination of neurotoxic shellfish toxins in shellfish extracts

1999 • 100 citations

Trends in treated ventricular fibrillation out-of-hospital cardiac arrest: A 17-year population-based study

2004 • 99 citations

Multiple ciguatoxins present in Indian Ocean reef fish

2002 • 97 citations

Differential actions of pacific ciguatoxin-1 on sodium channel subtypes in mammalian sensory neurons.

1999 • 95 citations

A radioimmunoassay for the detection of ciguatoxin

1977 • 94 citations

Environmental studies on a toxic dinoflagellate responsible for Ciguatera.

1980 • 87 citations

Sudden cardiac death in Hispanic Americans and African Americans.

1997 • 85 citations

Epidemiologic transition in the United States: the health factor in population change.

1977 • 84 citations

Poisoning, envenomation, and trauma from marine creatures.

2004 • 83 citations

Multiple ciguatoxins in the flesh of fish

1992 • 82 citations

Ciguatoxins are potent ichthyotoxins

1992 • 82 citations

Identification of Caribbean ciguatoxins as the cause of an outbreak of fish poisoning among U.S. soldiers in Haiti

1997 • 82 citations

Electrophysiological studies on ciguatera poisoning in man (Part II)

1991 • 80 citations

Block of voltage-gated potassium channels by Pacific ciguatoxin-1 contributes to increased neuronal excitability in rat sensory neurons

2004 • 77 citations

Clinical features of ciguatera fish poisoning: a study of the disease in the US Virgin Islands.

1982 • 75 citations

A rapid, simplified enzyme immunoassay stick test for the detection of ciguatoxin and related polyethers from fish tissues

1985 • 75 citations

Ciguatoxin enhances quantal transmitter release from frog motor nerve terminals

1990 • 74 citations

Pacific ciguatoxin‐1b effect over Na⁺ and K⁺ currents, inositol 1,4,5‐triphosphate content and intracellular Ca²⁺ signals in cultured rat myotubes

2002 • 72 citations

Travel and Ciguatera Fish Poisoning

1992 • 70 citations

Serum Sickness Following Administration of Antivenin (Crotalidae) Polyvalent in 181 Cases of Presumed Rattlesnake Envenomation☆

2003 • 70 citations

The Basis of the Paradoxical Disturbance of Temperature Perception in Ciguatera Poisoning

1993 • 69 citations

Traditional remedies used in the Western Pacific for the treatment of ciguatera poisoning

1992 • 68 citations

Born Unwanted: Developmental Effects of Denied Abortion

1989 • 68 citations

Study of an outbreak of ciguatera fish poisoning in Hong Kong

2005 • 67 citations

Effects of early maternal employment on toddlers, mothers, and fathers.

1985 • 67 citations

CIGUATERA IN THE PACIFIC: A LINK WITH MILITARY ACTIVITIES

1989 • 67 citations

Interaction of a granular stream with an obstacle

1998 • 66 citations

Ciguatera poisoning: a global issue with common management problems

2001 • 66 citations

Emergence of Cardiovascular Diseases in Developing Countries

1988 • 65 citations

Neurotoxin-Specific Immunoglobulins Accelerate Dissociation of the Neurotoxin-Acetylcholine Receptor Complex

1982 • 65 citations

Experimental Induction of Ciguatera Toxicity in Fish through Diet

1963 • 63 citations

A Simple Membrane Immunobead Assay for Detecting Ciguatoxin and Related Polyethers from Human Ciguatera Intoxication and Natural Reef Fishes

1998 • 63 citations

Neurotoxins targetting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons

1999 • 60 citations

Binding of brevetoxins and ciguatoxin to the voltage-sensitive sodium channel and conformational analysis of brevetoxin B

1992 • 59 citations

Isolation of two toxins from a parrotfish Scarus gibbus

1977 • 58 citations

Disease and development: Coguatera fish poisoning

1986 • 56 citations

Postpartum and Postabortion Psychotic Reactions

1981 • 55 citations

Review and Assessment of In Vitro Detection Methods for Algal Toxins

2001 • 55 citations

Dynamics of a Projectile Penetrating Sand. Part II

1957 • 54 citations

Treatment of Ciguatera Fish Poisoning with Amttriptyline and Nifedipine

1987 • 53 citations

Ciguatoxin reduces larval survivability in finfish

1999 • 53 citations

Ciguatera and mannitol: In Vivo and In Vitro assessment in mice

1993 • 51 citations

RECENT DEVELOPMENTS IN THE MOLECULAR STRUCTURE OF CIGUATOXIN

1987 • 50 citations

Allosteric modulation of neurotoxin binding to voltage-sensitive sodium channels by Ptychodiscus brevis toxin 2.

1987 • 50 citations

Assessment of efficacy of bothropic antivenom therapy on microcirculatory effects induced by Bothrops jararaca snake venom

2003 • 49 citations

Characterization of the developmental toxicity of Caribbean ciguatoxins in finfish embryos

2004 • 49 citations

Ability of some plant extracts, traditionally used to treat ciguatera fish poisoning, to prevent the in vitro neurotoxicity produced by sodium channel activators

2005 • 48 citations

Species selective resistance of cardiac muscle voltage gated sodium channels: Characterization of brevetoxin and ciguatoxin binding sites in rats and fish

2006 • 47 citations

Interobserver discordance in the classification of mechanisms of death in studies of heart failure

1995 • 47 citations

Recovery of ciguatoxin from fish flesh

1993 • 47 citations

Direct and indirect effects of ciguatoxin on guinea-pig atria and papillary muscles

1986 • 46 citations

Study of factors that influence the clinical response to ciguatera fish poisoning

1993 • 46 citations

Ciguatoxin (CTX-1) modulates single tetrodotoxin-sensitive sodium channels in rat parasympathetic neurones

1998 • 44 citations

Role of very low density lipoproteins in the accumulation of o,p′-DDT in fish ovaries during gonadal recrudescence

1996 • 43 citations

A pilot study of the cognitive and psychological correlates of chronic ciguatera poisoning

2003 • 42 citations

Chronic fatigue syndrome: chronic ciguatera poisoning as a differential diagnosis

1997 • 42 citations

Comparison of alfentanil and morphine in the prehospital treatment of patients with acute ischaemic-type chest pain

2001 • 42 citations

A Treatment Approach for Adolescents with Gambling Problems

2006 • 42 citations

Ciguatera Toxins Adversely Affect Piscivorous Fishes

1988 • 42 citations

Symptomatic improvement with amitriptyline in ciguatera fish poisoning.

1986 • 41 citations

Ciguatoxin‐induced oscillations in membrane potential and action potential firing in rat parasympathetic neurons

2002 • 41 citations

Trends in treated ventricular fibrillation in out-of-hospital cardiac arrest: Ischemic compared to non-ischemic heart disease

2005 • 39 citations

International Resuscitation Network Registry: design, rationale and preliminary results

2005 • 39 citations

Neuroprotectant effects of iso-osmolar d-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: A comparison with other osmotic agents and free radical scavengers

2005 • 37 citations

Effects of Ciguatera Toxins on the Bluehead

1986 • 37 citations

Ciguatera fish poisoning: a review

2001 • 37 citations

Reproductive Behavior, Central and Eastern European Experience

1982 • 36 citations

Mild ciguatera poisoning: Case reports with neurophysiological evaluations

2000 • 35 citations

Caribbean ciguatera: a changing paradigm.

2004 • 34 citations

Neuroexcitatory actions of ciguatoxin on brain regions associated with thermoregulation

1995 • 34 citations

United States and Denmark: Different Approaches to Health Care and Family Planning

1990 • 32 citations

The clinical utility of QT interval assessment in diabetes.

2000 • 32 citations

Characterization of mice antisera elicited with a ciguatoxin tetracyclic synthetic ring fragment (JKLM) conjugated to carrier proteins

2000 • 31 citations

Ciguatoxin extracted from poisonous moray eels Gymnothorax javanicus triggers acetylcholine release from Torpedo cholinergic synaptosomes via reversed Na+ –Ca2+ exchange

1993 • 30 citations

Sodium channel toxins and neurotransmitter release.

2003 • 27 citations

The origin of ciguatera in Platypus Bay, Australia

1994 • 27 citations

Ciguatera I: Brine Shrimp (Artemia salina L.) Larval Assay for Ciguatera Toxins

1976 • 27 citations

Electrical activity in rat tail artery during asynchronous activation of postganglionic nerve terminals by ciguatoxin‐1

1995 • 25 citations

[Evaluation of the efficacy of mannitol in the treatment of ciguatera in French Polynesia].

1992 • 25 citations

Three clusters of ciguatera poisoning: clinical manifestations and public health implications

2000 • 25 citations

Progress on chemical knowledge of ciguatoxins.

1992 • 24 citations

Negative inotropic and arrhythmic effects of high doses of ciguatoxin on guinea-pig atria and papillary muscles

1988 • 24 citations

Brevetoxin augments NMDA receptor signaling in murine neocortical neurons

2004 • 22 citations

Documented case of ciguatera on the Mexican Pacific Coast

1995 • 22 citations

Toxicological biotest on Diptera larvae to detect ciguatoxins and various other toxic substances

1996 • 22 citations

Improvements in the sensitivity of inverse-detected heteronuclear correlation spectra using micro inverse probes and micro cells: HMQC and HMBC spectra of caribbean ciguatoxin — preliminary structural inferences

1995 • 22 citations

Thermal stability studies of hyperimmune horse antivenoms

1999 • 21 citations

Reversal of pacific ciguatoxin-1B effects on myelinated axons by agents used in ciguatera treatment

2000 • 21 citations

Ciguatera: Current concepts

1995 • 20 citations

Measuring survival rates from sudden cardiac arrest: the elusive definition

2004 • 20 citations

The Iowa Department of Public Health Gambling Treatment Services: Four Years of Evidence

2002 • 20 citations

A rapid assay for the brevetoxin group of sodium channel activators based on fluorescence monitoring of synaptoneurosomal membrane potential

2003 • 20 citations

Chronic Ciguatera

1996 • 20 citations

Les modes de prévention des naissances en Europe de l'Est

1991 • 19 citations

Marine toxins from the Pacific—IX

1971 • 19 citations

Reconsidering population policies: ethics development and strategies for change.

1994 • 19 citations

Youth and technology: the case of gambling, video-game playing and the Internet

2004 • 19 citations

Effects of marine algal toxins on thermoregulation in mice

2005 • 18 citations

Epidemiology of Seafood Poisoning

2018 • 16 citations

Inhibition of Toxic Activities ofVenom and Other Crotalid Snake Venoms by a Novel Neutralizing Mixture

1997 • 15 citations

Chronic phase lipids in sera of chronic fatigue syndrome (CFS), chronic ciguatera fish poisoning (CCFP), hepatitis B, and cancer with antigenic epitope resembling ciguatoxin, as assessed with MAb‐CTX

2003 • 13 citations

CIGUATERA POISONING IN VANUATU

2003 • 13 citations

Seafood Toxins and Seafood Products

1993 • 12 citations

Ultrastructural alterations of cabrilla sea bass Serranus cabrilla liver related to experimental Gambierdlscus toxicus (dinoflagellate) ingestion

1994 • 11 citations

Biological activity of the functional epitope of ciguatoxin fragment AB on the neuroblastoma sodium channel in tissue culture

2006 • 11 citations

Chronic Phase Lipids in Sera of Several Chronic Diseases Reacting with MAB–CTX (Antibody to Ciguatoxin)

2003 • 7 citations

Recent Developments in Abortion Law in Industrialized Countries

1990 • 4 citations

Czechoslovakia 1991: abortion and contraception.

1991 • 2 citations

Deleted Work

1955 • 0 citations