Gene therapy of apolipoprotein E–deficient mice using a novel macrophage-specific retroviral vector

Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease

2000 • 2,632 citations

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo

2000 • 2,366 citations

Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

1998 • 1,775 citations

The Basic Science of Gene Therapy

1993 • 1,767 citations

Development of a Self-Inactivating Lentivirus Vector

1998 • 1,169 citations

Episomal Vectors Rapidly and Stably Produce High-Titer Recombinant Retrovirus

1996 • 768 citations

Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin

2000 • 567 citations

Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

1996 • 565 citations

Correction of Sickle Cell Disease in Transgenic Mouse Models by Gene Therapy

2001 • 563 citations

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.

1986 • 533 citations

Prevention of Atherosclerosis in Apolipoprotein E-Deficient Mice by Bone Marrow Transplantation

1995 • 467 citations

Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism

1984 • 440 citations

Atherosclerosis and Coronary Artery Disease

1996 • 438 citations

Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo.

1994 • 415 citations

Inflammatory Cells and Cancer

2001 • 394 citations

Improved Methods of Retroviral Vector Transduction and Production for Gene Therapy

1994 • 382 citations

Serial Analysis of Gene Expression in Human Monocytes and Macrophages

1999 • 241 citations

Toso, a Cell Surface, Specific Regulator of Fas-Induced Apoptosis in T Cells

1998 • 224 citations

Oxford textbook of pathology

2013 • 220 citations

Oxford Textbook of Pathology

1994 • 210 citations

Treatment of severe hypercholesterolemia in apolipoprotein E-deficient mice by bone marrow transplantation.

1995 • 208 citations

Self-Inactivating Lentiviral Vectors with U3 and U5 Modifications

1999 • 185 citations

Progress in Transcriptionally Targeted and Regulatable Vectors for Genetic Therapy

1997 • 180 citations

Gene silencing as a threat to the success of gene therapy

2000 • 178 citations

Autocrine Deactivation of Macrophages in Transgenic Mice Constitutively Overexpressing IL-10 Under Control of the Human CD68 Promoter

2002 • 175 citations

Cells expressing human glucocerebrosidase from a retroviral vector repopulate macrophages and central nervous system microglia after murine bone marrow transplantation

1994 • 166 citations

Analysis of Macrophage Scavenger Receptor (SR-A) Expression in Human Aortic Atherosclerotic Lesions

1999 • 136 citations

High-level erythroid-specific gene expression in primary human and murine hematopoietic cells with self-inactivating lentiviral vectors

2001 • 119 citations

Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny

2000 • 115 citations

Retroviral Gene Therapy in ApoE-Deficient Mice

1999 • 103 citations

High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters

1984 • 96 citations

The use of human CD68 transcriptional regulatory sequences to direct high‐level expression of class A scavenger receptor in macrophages in vitro and in vivo

2001 • 95 citations

Long-term cure of the photosensitivity of murine erythropoietic protoporphyria by preselective gene therapy

1999 • 88 citations

Preselective gene therapy for Fabry disease

2001 • 74 citations

GENE TRANSFER TO HEMATOPOIETIC STEM CELLS: Implications for Gene Therapy of Human Disease

1996 • 72 citations

Functional Comparison of the Murine Macrosialin and Human CD68 Promoters in Macrophage and Nonmacrophage Cell Lines

1998 • 47 citations

Gene therapy for the hemoglobin disorders: Past, present, and future

2000 • 36 citations

Inactivation of a GFP retrovirus occurs at multiple levels in long-term repopulating stem cells and their differentiated progeny

2000 • 27 citations

Effects of CD2 locus control region sequences on gene expression by retroviral and lentiviral vectors

2001 • 25 citations

The Linked Human Elongation Initiation Factor 4A1 (EIF4A1) and CD68 Genes Map to Chromosome 17p13

1998 • 15 citations