Self-Inactivating Lentivirus Vector for Safe and Efficient In Vivo Gene Delivery

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

1996 • 4,854 citations

A Third-Generation Lentivirus Vector with a Conditional Packaging System

1998 • 3,175 citations

Multiply attenuated lentiviral vector achieves efficient gene delivery in vivo

1997 • 1,977 citations

Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector.

1996 • 1,516 citations

Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector

1997 • 732 citations

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

1997 • 614 citations

Self-inactivating retroviral vectors designed for transfer of whole genes into mammalian cells.

1986 • 533 citations

Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesis

1984 • 368 citations

Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation

1986 • 312 citations

Alternative Mechanisms for Activation of Human Immunodeficiency Virus Enhancer in T Cells

1988 • 265 citations

kat: a high-efficiency retroviral transduction system for primary human T lymphocytes

1994 • 225 citations

Inhibition of HMGI-C Protein Synthesis Suppresses Retrovirally Induced Neoplastic Transformation of Rat Thyroid Cells

1995 • 195 citations

The human immunodeficiency virus type 1 polyadenylylation signal: a 3' long terminal repeat element upstream of the AAUAAA necessary for efficient polyadenylylation.

1991 • 136 citations

Cooperative interaction of Ets-1 with USF-1 required for HIV-1 enhancer activity in T cells

1998 • 133 citations

Gene expression from transcriptionally disabled retroviral vectors.

1987 • 120 citations

A human cell factor is essential for HIV-1 Rev action.

1990 • 120 citations

A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing.

1987 • 100 citations

Promoter interactions in retrovirus vectors introduced into fibroblasts and embryonic stem cells

1991 • 95 citations

Involvement of long terminal repeat U3 sequences overlapping the transcription control region in human immunodeficiency virus type 1 mRNA 3' end formation.

1991 • 79 citations

A human binding site for transcription factor USF/MLTF mimics the negative regulatory element of human immunodeficiency virus type 1

1992 • 75 citations

Handicapped retroviral vectors efficiently transduce foreign genes into hematopoietic stem cells.

1987 • 73 citations

Elements upstream of the AAUAAA within the human immunodeficiency virus polyadenylation signal are required for efficient polyadenylation in vitro.

1992 • 73 citations

Naturally occurring genotypes of the human immunodeficiency virus type 1 long terminal repeat display a wide range of basal and Tat-induced transcriptional activities

1994 • 71 citations

Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes

1994 • 65 citations

Quantitative evaluation of liver-specific promoters from retroviral vectors after in vivo transduction of hepatocytes

1994 • 62 citations

Involvement of Long Terminal Repeat U3 Sequences Overlapping the Transcription Control Region in Human Immunodeficiency Virus Type 1 mRNA 3′ End Formation

1991 • 43 citations

Unusually high frequency of reconstitution of long terminal repeats in U3-minus retrovirus vectors by DNA recombination or gene conversion

1992 • 38 citations

Elements Upstream of the AAUAAA within the Human Immunodeficiency Virus Polyadenylation Signal Are Required for Efficient Polyadenylation In Vitro

1992 • 30 citations

Improved self-inactivating retroviral vectors derived from spleen necrosis virus

1994 • 30 citations

Retroviral Vector Sequences May Interact with Some Internal Promoters and Influence Expression

1996 • 27 citations

The pattern of integration of viral DNA sequences in the adenovirus 5-transformed human cell line 293

1983 • 22 citations

A conditional self-inactivating retrovirus vector that uses a tetracycline-responsive expression system

1997 • 21 citations

Importance of 3' non-coding sequences for efficient retrovirus-mediated gene transfer in avian cells revealed by self-inactivating vectors

1993 • 13 citations

Improved gene expression by a U3-based retroviral vector

1992 • 9 citations