The Vaccinia Virus F1L Protein Interacts with the Proapoptotic Protein Bak and Inhibits Bak Activation

The biochemistry of apoptosis

2000 • 7,314 citations

Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy

2017 • 4,947 citations

Cleavage of BID by Caspase 8 Mediates the Mitochondrial Damage in the Fas Pathway of Apoptosis

1998 • 4,383 citations

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

2001 • 3,867 citations

BCL-2 family members and the mitochondria in apoptosis

1999 • 3,657 citations

The Pathophysiology of Mitochondrial Cell Death

2004 • 3,258 citations

Mitochondrial control of cell death

2000 • 3,098 citations

The expanding role of mitochondria in apoptosis.

2001 • 2,377 citations

Movement of Bax from the Cytosol to Mitochondria during Apoptosis

1997 • 1,805 citations

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

2005 • 1,751 citations

The Bcl-2 family: roles in cell survival and oncogenesis

2003 • 1,448 citations

Bid, Bax, and Lipids Cooperate to Form Supramolecular Openings in the Outer Mitochondrial Membrane

2002 • 1,443 citations

The Combined Functions of Proapoptotic Bcl-2 Family Members Bak and Bax Are Essential for Normal Development of Multiple Tissues

2000 • 1,427 citations

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

2000 • 1,245 citations

BH3 Domains of BH3-Only Proteins Differentially Regulate Bax-Mediated Mitochondrial Membrane Permeabilization Both Directly and Indirectly

2005 • 1,152 citations

Bid Induces the Oligomerization and Insertion of Bax into the Outer Mitochondrial Membrane

2000 • 1,150 citations

Viral Subversion of the Immune System

2000 • 833 citations

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

2003 • 789 citations

Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex

2004 • 748 citations

Mechanisms of cytochrome c release by proapoptotic BCL-2 family members

2003 • 705 citations

Bax Is Present as a High Molecular Weight Oligomer/Complex in the Mitochondrial Membrane of Apoptotic Cells

2001 • 676 citations

Poxviruses and Immune Evasion

2003 • 639 citations

The role of BH3-only proteins in the immune system

2005 • 608 citations

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

2003 • 588 citations

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

2003 • 586 citations

Apoptosis in the development and maintenance of the immune system

2003 • 524 citations

Cell Damage-induced Conformational Changes of the Pro-Apoptotic Protein Bak In Vivo Precede the Onset of Apoptosis

1999 • 485 citations

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2

1999 • 422 citations

Establishment of Monoclonal Anti-Nk-1.1 Antibody

1984 • 360 citations

The Genome of Fowlpox Virus

2000 • 326 citations

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

2003 • 307 citations

Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection

2002 • 280 citations

Vaccinia virus immune evasion

1997 • 242 citations

Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes

1998 • 196 citations

Cytomegalovirus cell death suppressor vMIA blocks Bax- but not Bak-mediated apoptosis by binding and sequestering Bax at mitochondria

2004 • 193 citations

The Genome of Canarypox Virus

2003 • 189 citations

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

2002 • 163 citations

Viral proteins targeting mitochondria: controlling cell death

2004 • 162 citations

Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosis

2003 • 151 citations

BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization

2003 • 144 citations

M11l

2000 • 131 citations

Deletion analysis of two tandemly arranged virulence genes in myxoma virus, M11L and myxoma growth factor

1992 • 127 citations

An Anti-apoptotic Viral Protein That Recruits Bax to Mitochondria

2004 • 123 citations

Tumor Necrosis Factor-α Induces Bax-Bak Interaction and Apoptosis, Which Is Inhibited by Adenovirus E1B 19K

2001 • 119 citations

NEW EMBO MEMBERS' REVIEW: Viral and bacterial proteins regulating apoptosis at the mitochondrial level

2001 • 117 citations

Expression of the Myxoma Virus Tumor Necrosis Factor Receptor Homologue and M11L Genes Is Required to Prevent Virus-Induced Apoptosis in Infected Rabbit T Lymphocytes

1996 • 116 citations

Generation of Recombinant Vaccinia Viruses

2015 • 114 citations

Kaposi's Sarcoma-Associated Herpesvirus Mitochondrial K7 Protein Targets a Cellular Calcium-Modulating Cyclophilin Ligand To Modulate Intracellular Calcium Concentration and Inhibit Apoptosis

2002 • 100 citations

The Myxoma Poxvirus Protein, M11L, Prevents Apoptosis by Direct Interaction with the Mitochondrial Permeability Transition Pore

2002 • 99 citations

Distinct Domains Control the Addressing and the Insertion of Bax into Mitochondria

2004 • 94 citations

Human cytomegalovirus proteins encoded by UL37 exon 1 protect infected fibroblasts against virus-induced apoptosis and are required for efficient virus replication

2004 • 88 citations

Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak

2001 • 86 citations

Myxoma Virus M11L Prevents Apoptosis through Constitutive Interaction with Bak

2004 • 86 citations

Bak and Bax Function To Limit Adenovirus Replication through Apoptosis Induction

2002 • 85 citations

Resistance to Granzyme B-mediated Cytochrome c Release in Bak-deficient Cells

2001 • 71 citations

Viral Bcl-2 homologs and their role in virus replication and associated diseases

2003 • 70 citations

Modified vaccinia virus Ankara protein F1L is a novel BH3-domain-binding protein and acts together with the early viral protein E3L to block virus-associated apoptosis

2005 • 68 citations

Poxviruses and apoptosis: a time to die

2002 • 65 citations

Vaccinia Virus F1L Protein Is a Tail-Anchored Protein That Functions at the Mitochondria To Inhibit Apoptosis

2004 • 64 citations

Viral versus cellular BCL-2 proteins

2003 • 57 citations

Vaccinia Virus Infection Disarms the Mitochondrion-Mediated Pathway of the Apoptotic Cascade by Modulating the Permeability Transition Pore

2001 • 53 citations

Apoptosis Regulator Genes Encoded by Poxviruses

2004 • 24 citations