Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

A model for p53-induced apoptosis

1997 • 2,502 citations

Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.

1995 • 1,556 citations

Mitochondrial control of apoptosis

1997 • 1,500 citations

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

1997 • 1,389 citations

Mitochondrial control of nuclear apoptosis.

1996 • 1,363 citations

Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

1995 • 1,179 citations

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.

1996 • 1,143 citations

JC‐1, but not DiOC₆(3) or rhodamine 123, is a reliable fluorescent probe to assess ΔΨ changes in intact cells: implications for studies on mitochondrial functionality during apoptosis

1997 • 982 citations

Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

1986 • 782 citations

Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA

1993 • 758 citations

The Central Executioner of Apoptosis: Multiple Connections between Protease Activation and Mitochondria in Fas/APO-1/CD95- and Ceramide-induced Apoptosis

1997 • 625 citations

Alterations in mitochondrial structure and function are early events of dexamethasone-induced thymocyte apoptosis.

1995 • 598 citations

Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis

1996 • 440 citations

Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.

1996 • 353 citations

Selective targeting of bioactive compounds to mitochondria

1997 • 344 citations

Mitochondrial permeability transition in hepatocytes induced by t-BuOOH: NAD(P)H and reactive oxygen species

1997 • 336 citations

10N‐Nonyl acridine orange interacts with cardiolipin and allows the quantification of this phospholipid in isolated mitochondria

1992 • 320 citations

Protective Effect of N-Acetylcysteine in Tumor Necrosis Factor-α-Induced Apoptosis in U937 Cells: The Role of Mitochondria

1995 • 274 citations

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.

1997 • 259 citations

Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body.

1992 • 246 citations

A mitochondrial membrane protein defined by a novel monoclonal antibody is preferentially detected in apoptotic cells.

1996 • 229 citations

Loss of Function of Cytochrome c in Jurkat Cells Undergoing Fas-mediated Apoptosis

1996 • 225 citations

Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.

1996 • 202 citations

Release of Cytochrome c from Liver Mitochondria during Permeability Transition

1997 • 197 citations

Establishment of a Cell-Free System of Neuronal Apoptosis: Comparison of Premitochondrial, Mitochondrial, and Postmitochondrial Phases

1997 • 188 citations

Chloromethyl-X-rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis

1996 • 178 citations

High Density Distribution of Endoplasmic Reticulum Proteins and Mitochondria at Specialized Ca2+ Release Sites in Oligodendrocyte Processes

1997 • 167 citations

Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria

1984 • 132 citations

Selective damage to carcinoma mitochondria by the rhodacyanine MKT-077.

1996 • 123 citations

Cellular Events in Fas/APO-1-Mediated Apoptosis in JURKAT T Lymphocytes

1995 • 105 citations

A fast kinetic method for assessing mitochondrial membrane potential in isolated hepatocytes with rhodamine 123 and flow cytometry

1994 • 84 citations

Relationships between rhodamine 123 transport, cell volume, and ion-channel function of P-glycoprotein.

1994 • 59 citations

A critical evaluation of in situ measurement of mitochondrial electrical potentials in single hepatocytes

1996 • 44 citations

The effects of mitochondrial energetics inhibitors on the fluorescence of potential-sensitive dyes rhodamine 123 and DiS-C3-(5) in lymphocyte suspensions

1986 • 8 citations