Inhibition of desmin expression blocks myoblast fusion and interferes with the myogenic regulators MyoD and myogenin

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Mechanotransduction Across the Cell Surface and Through the Cytoskeleton

1993 • 2,947 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Position-independent, high-level expression of the human β-globin gene in transgenic mice

1987 • 1,955 citations

The myoD Gene Family: Nodal Point During Specification of the Muscle Cell Lineage

1991 • 1,564 citations

MOLECULAR AND CELLULAR BIOLOGY OF INTERMEDIATE FILAMENTS

1988 • 1,395 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene

1993 • 1,314 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

Immunochemical analysis of myosin heavy chain during avian myogenesis in vivo and in vitro.

1982 • 932 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence

1989 • 914 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD1: A Nuclear Phosphoprotein Requiring a Myc Homology Region to Convert Fibroblasts to Myoblasts

1988 • 839 citations

Cytoplasmic activation of human nuclear genes in stable heterocaryons

1983 • 839 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

MyoD family: a paradigm for development?

1990 • 776 citations

Cyclic AMP-Responsive DNA-Binding Protein: Structure Based on a Cloned Placental cDNA

1988 • 772 citations

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1989 • 662 citations

Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analyses

1991 • 647 citations

Common DNA binding site for Fos protein complexesand transcription factor AP-1

1988 • 613 citations

A nuclear DNA attachment element mediates elevated and position-independent gene activity

1989 • 597 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1993 • 550 citations

Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition.

1984 • 545 citations

Analysis of FBJ-MuSV provirus and c-fos (mouse) gene reveals that viral and cellular fos gene products have different carboxy termini

1983 • 532 citations

fos-associated cellular p39 is related to nuclear transcription factor AP-1

1988 • 508 citations

Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.

1990 • 508 citations

Herculin, a fourth member of the MyoD family of myogenic regulatory genes.

1990 • 482 citations

Construction of plasmids that expressE.coli β-galactosidase in mammalian cells

1989 • 458 citations

The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.

1982 • 432 citations

Functional antagonism between c-Jun and MyoD proteins: A direct physical association

1992 • 424 citations

Immunological characterization of the subunit of the 100 A filaments from muscle cells.

1976 • 419 citations

Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease

1991 • 413 citations

Regulation of myogenic differentiation by type beta transforming growth factor.

1986 • 408 citations

MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes.

1990 • 393 citations

Reduction of polygalacturonase activity in tomato fruit by antisense RNA

1988 • 381 citations

Mutations in the Rod Domains of Keratins 1 and 10 in Epidermolytic Hyperkeratosis

1992 • 370 citations

The genetic basis of epidermolytic hyperkeratosis: A disorder of differentiation-specific epidermal keratin genes

1992 • 339 citations

Stable reduction of thymidine kinase activity in cells expressing high levels of anti-sense RNA

1985 • 334 citations

Desmin and vimentin coexist at the periphery of the myofibril Z disc

1979 • 327 citations

Binding of matrix attachment regions to lamin B1

1992 • 318 citations

The synthesis and distribution of desmin and vimentin during myogenesis in vitro

1980 • 312 citations

The organisation of chromatin loops: characterization of a scaffold attachment site

1986 • 308 citations

Lamin B constitutes an intermediate filament attachment site at the nuclear envelope.

1987 • 306 citations

Myogenesis in the mouse embryo: differential onset of expression of myogenic proteins and the involvement of titin in myofibril assembly.

1989 • 297 citations

A leucine→proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis

1992 • 284 citations

The matrix attachment regions of the chicken lysozyme gene co-map with the boundaries of the chromatin domain.

1988 • 280 citations

The chicken lysozyme 5' matrix attachment region increases transcription from a heterologous promoter in heterologous cells and dampens position effects on the expression of transfected genes.

1990 • 276 citations

Cyclic amplification and selection of targets (CASTing) for the myogenin consensus binding site.

1991 • 275 citations

The relationship between stress fiber-like structures and nascent myofibrils in cultured cardiac myocytes.

1984 • 264 citations

Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression.

1992 • 250 citations

Genetic complementation reveals a novel regulatory role for 3? untranslated regions in growth and differentiation

1993 • 245 citations

Redistribution of intermediate filament subunits during skeletal myogenesis and maturation in vitro.

1979 • 242 citations

Suppression by antisense mRNA demonstrates a requirement for the glial fibrillary acidic protein in the formation of stable astrocytic processes in response to neurons.

1991 • 241 citations

Intermediate Filaments

1982 • 236 citations

Two distinct attachment sites for vimentin along the plasma membrane and the nuclear envelope in avian erythrocytes: a basis for a vectorial assembly of intermediate filaments.

1987 • 227 citations

Nuclear scaffold attachment sites in the human globin gene complexes.

1988 • 225 citations

Replicating myoblasts express a muscle-specific phenotype.

1988 • 206 citations

Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis.

1992 • 178 citations

Functions of intermediate filaments

1989 • 178 citations

Intermediate Filaments: A Review

2011 • 169 citations

Intermediate Filaments: Possible Functions as Cytoskeletal Connecting Links Between the Nucleus and the Cell Surface^a

1985 • 160 citations

Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.

1991 • 159 citations

Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor.

1984 • 155 citations

Distributions of vimentin and desmin in developing chick myotubes in vivo. I. Immunofluorescence study.

1984 • 153 citations

Binding of two desmin derivatives to the plasma membrane and the nuclear envelope of avian erythrocytes: evidence for a conserved site-specificity in intermediate filament-membrane interactions.

1987 • 146 citations

Titin and myosin, but not desmin, are linked during myofibrillogenesis in postmitotic mononucleated myoblasts.

1986 • 142 citations

Structural associations of synemin and vimentin filaments in avian erythrocytes revealed by immunoelectron microscopy

1982 • 139 citations

Overexpression of the vimentin gene in transgenic mice inhibits normal lens cell differentiation.

1989 • 139 citations

Desmin is present in proliferating rat muscle satellite cells but not in bovine muscle satellite cells

1991 • 124 citations

Tissue-specific expression of two mRNA species transcribed from a single vimentin gene

1983 • 123 citations

Molecular biology of neuronal intermediate filaments

1993 • 123 citations

Localized maternal mRNA related to transforming growth factor beta mRNA is concentrated in a cytokeratin-enriched fraction from Xenopus oocytes.

1988 • 123 citations

Myogenesis and developmental control genes

1990 • 121 citations

MyoD, myogenin independent differentiation of primordial myoblasts in mouse somites.

1992 • 115 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

Intermediate-size Filaments: Changes in Synthesis and Distribution in Cells of the Myogenic and Neurogenic Lineages

1982 • 111 citations

Aberrant regulation of MyoD1 contributes to the partially defective myogenic phenotype of BC3H1 cells [published erratum appears in J Cell Biol 1990 Jun;110(6):2231]

1990 • 109 citations

Desmin and titin expression in early postimplantation mouse embryos

1989 • 107 citations

The cellular and molecular biology of keratins: beginning a new era

1993 • 107 citations

Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments

1991 • 106 citations

Regulation of the mouse desmin gene: transactivation by MyoD, myogenin, MRF4 and Myf5

1993 • 104 citations

Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development

1989 • 103 citations

Immunocytochemical analysis of intermediate filaments in embryonic heart cells with monoclonal antibodies to desmin.

1984 • 99 citations

Desmin/vimentin intermediate filaments are dispensable for many aspects of myogenesis.

1991 • 96 citations

Desmin- and Vimentin-containing Filaments and Their Role in the Assembly of the Z Disk in Muscle Cells

1982 • 95 citations

Cyclic Amplification and Selection of Targets (CASTing) for the Myogenin Consensus Binding Site

1991 • 77 citations

The Chicken Lysozyme 5′ Matrix Attachment Region Increases Transcription from a Heterologous Promoter in Heterologous Cells and Dampens Position Effects on the Expression of Transfected Genes

1990 • 75 citations

Expression of intermediate filament proteins during development of Xenopus laevis: II. Identification and molecular characterization of desmin

1989 • 62 citations

Characterization and regulation in the expression of a gene coding for the intermediate filament protein desmin.

1984 • 61 citations

Plasma membrane-cytoskeleton damage in eye lenses of transgenic mice expressing desmin.

1990 • 59 citations

The binding in vitro of the intermediate filament protein vimentin to synthetic oligonucleotides containing telomere sequences.

1988 • 55 citations

Nucleus-associated intermediate filaments from chicken erythrocytes.

1980 • 55 citations

Definition and identification of homology domains

1988 • 46 citations

Mouse vimentin: structural relationship to fos, jun, CREB and tpr.

1990 • 39 citations

Intermediate Filaments in Striated Muscle

1983 • 36 citations

Developmental regulation of intermediate filament and actin mRNAs during myogenesis is disrupted by oncogenic ras genes.

1989 • 35 citations

Intermediate filaments in striated muscle. A review of structural studies in embryonic and adult skeletal and cardiac muscle.

1983 • 33 citations

Tissue-specific expression of a vimentin-desmin hybrid gene in transgenic mice.

1988 • 32 citations

Identification of attachment proteins for DNA in Chinese hamster ovary cells.

1988 • 29 citations

Monoclonal Antibodies to Desmin: Evidence for Stage‐dependent Intermediate Filament Immunoreactivity during Cardiac and Skeletal Muscle Development^a

1985 • 27 citations

Expression of the chicken vimentin gene in transgenic mice: efficient assembly of the avian protein into the cytoskeleton.

1989 • 24 citations

The Role of Intermediate (10-nm) Filaments in the Development and Integration of the Myofibrillar Contractile Apparatus in the Embryonic Mammalian Heart

1981 • 22 citations

Antisense RNA inhibition of HPRT synthesis

1990 • 15 citations