Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: Genetic and functional analyses

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

PCR protocols — A guide to methods and applications

1990 • 10,078 citations

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is

1975 • 4,443 citations

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Changes in keratin gene expression during terminal differentiation of the keratinocyte

1980 • 1,059 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

The mesothelial keratins: A new family of cytoskeletal proteins identified in cultured mesothelial cells and nonkeratinizing epithelia

1982 • 523 citations

Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa

1991 • 511 citations

Keratin filaments of cultured human epidermal cells. Formation of intermolecular disulfide bonds during terminal differentiation.

1978 • 501 citations

AMPLIFICATION OF RNA

1990 • 486 citations

Mutant keratin expression in transgenic mice causes marked abnormalities resembling a human genetic skin disease

1991 • 413 citations

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.

1988 • 359 citations

The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies.

1983 • 355 citations

The cDNA sequence of a human epidermal keratin: Divergence of sequence but conservation of structure among intermediate filament proteins

1982 • 298 citations

A new small (40 kd) keratin filament protein made by some cultured human squamous cell carcinomas

1981 • 254 citations

Elucidating the early stages of keratin filament assembly.

1990 • 243 citations

The expression of mutant epidermal keratin cDNAs transfected in simple epithelial and squamous cell carcinoma lines.

1987 • 237 citations

Expression of mutant keratin cDNAs in epithelial cells reveals possible mechanisms for initiation and assembly of intermediate filaments.

1989 • 210 citations

Expression of keratin K14 in the epidermis and hair follicle: insights into complex programs of differentiation.

1989 • 196 citations

Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins

1987 • 187 citations

Assembly properties of dominant and recessive mutations in the small mouse neurofilament (NF-L) subunit.

1990 • 173 citations

Remarkable conservation of structure among intermediate filament genes

1984 • 169 citations

Retrovirus-mediated transgenic keratin expression in cultured fibroblasts: Specific domain functions in keratin stabilization and filament formation

1990 • 165 citations

Structure of a gene for the human epidermal 67-kDa keratin.

1985 • 160 citations

Type I and type II keratins have evolved from lower eukaryotes to form the epidermal intermediate filaments in mammalian skin.

1983 • 146 citations

Protein complexes of intermediate-sized filaments: melting of cytokeratin complexes in urea reveals different polypeptide separation characteristics.

1983 • 143 citations

A group of type I keratin genes on human chromosome 17: characterization and expression.

1988 • 142 citations

Deletions in epidermal keratins leading to alterations in filament organization in vivo and in intermediate filament assembly in vitro.

1990 • 135 citations

Structure of an invertebrate gene encoding cytoplasmic intermediate filament (IF) proteins: implications for the origin and the diversification of IF proteins.

1990 • 127 citations

Unifying principles in intermediate filament (IF) structure and assembly

1988 • 124 citations

Primary and secondary structure of hamster vimentin predicted from the nucleotide sequence.

1983 • 121 citations

Characterization of dominant and recessive assembly-defective mutations in mouse neurofilament NF-M.

1990 • 116 citations

Modulation of keratin intermediate filament assembly by single amino acid exchanges in the consensus sequence at the C-terminal end of the rod domain

1991 • 109 citations

Genetically Induced Abnormalities of Epidermal Differentiation and Ultrastructure in Ichthyoses and Epidermolyses: Pathogenesis, heterogeneity, Fetal Manifestation, and Prenatal Diagnosis

1983 • 101 citations

Dermatology in General Medicine

1972 • 82 citations

Abnormal organization of keratin intermediate filaments in cultured keratinocytes of epidermolysis bullosa simplex

1989 • 74 citations

Ultrastructure of Blister Formation in Epidermolysis Bullosa Hereditaria: V. Epidermolysis Bullosa Simplex Localisata Type Weber-Cockayne

1982 • 67 citations

Three epidermal and one simple epithelial type II keratin genes map to human chromosome 12

1991 • 62 citations

Tailless keratins assemble into regular intermediate filaments in vitro

1990 • 62 citations

Deficiency of Galactosylhydroxylysyl Glucosyltransferase, an Enzyme of Collagen Synthesis, in a Family with Dominant Epidermolysis Bullosa Simplex

1981 • 55 citations

Generalized Dominant Epidermolysis Bullosa Simplex: Decreased Activity of a Gelatinolytic Protease in Cultured Fibroblasts as a Phenotypic Marker

1983 • 36 citations

Epidermolysis Bullosa Simplex (Koebner) Is a Keratin Disorder

1991 • 34 citations

Inactivation of human keratin genes: the spectrum of mutations in the sequence of an acidic keratin pseudogene.

1988 • 29 citations

A Specific Defect in Glycosylation of Epidermal Cell Membranes

1985 • 21 citations

Epidermolysis Bullosa Simplex: Identification of a Kindred with Autosomal Recessive Transmission of the Weher‐Cockayne Variety

1989 • 18 citations

Epidermolysis bullosa simplex (Koebner) is a keratin disorder. Ultrastructural and immunohistochemical study

1991 • 8 citations

A specific defect in glycosylation of epidermal cell membranes. Definition in skin from patients with epidermolysis bullosa simplex

1985 • 8 citations