Regulation of the mouse desmin gene: transactivation by MyoD, myogenin, MRF4 and Myf5

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Expression of a single transfected cDNA converts fibroblasts to myoblasts

1987 • 3,373 citations

Basic Methods in Molecular Biology

1986 • 3,284 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins

1989 • 2,706 citations

Serial passaging and differentiation of myogenic cells isolated from dystrophic mouse muscle

1977 • 2,070 citations

DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells.

1979 • 1,339 citations

Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD

1989 • 1,286 citations

Intermediate Filaments: A Chemically Heterogeneous, Developmentally Regulated Class of Proteins

1982 • 1,021 citations

Differences and Similarities in DNA-Binding Preferences of MyoD and E2A Protein Complexes Revealed by Binding Site Selection

1990 • 957 citations

A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts.

1989 • 919 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

A gene with homology to the myc similarity region of MyoD1 is expressed during myogenesis and is sufficient to activate the muscle differentiation program.

1989 • 863 citations

MyoD is a sequence-specific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer

1989 • 861 citations

Cytoplasmic activation of human nuclear genes in stable heterocaryons

1983 • 839 citations

The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation

1990 • 794 citations

Identification of MRF4: a new member of the muscle regulatory factor gene family.

1989 • 779 citations

MyoD family: a paradigm for development?

1990 • 776 citations

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

1989 • 662 citations

A new myocyte-specific enhancer-binding factor that recognizes a conserved element associated with multiple muscle-specific genes.

1989 • 605 citations

Myf-6, a new member of the human gene family of myogenic determination factors: evidence for a gene cluster on chromosome 12.

1990 • 508 citations

Herculin, a fourth member of the MyoD family of myogenic regulatory genes.

1990 • 482 citations

Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.

1986 • 432 citations

MyoD converts primary dermal fibroblasts, chondroblasts, smooth muscle, and retinal pigmented epithelial cells into striated mononucleated myoblasts and multinucleated myotubes.

1990 • 393 citations

Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene.

1989 • 326 citations

The synthesis and distribution of desmin and vimentin during myogenesis in vitro

1980 • 312 citations

Myogenin induces the myocyte-specific enhancer binding factor MEF-2 independently of other muscle-specific gene products.

1991 • 264 citations

Identification of upstream and intragenic regulatory elements that confer cell-type-restricted and differentiation-specific expression on the muscle creatine kinase gene.

1988 • 248 citations

A muscle-specific enhancer is located at the 3' end of the myosin light-chain 1/3 gene locus.

1988 • 212 citations

Replicating myoblasts express a muscle-specific phenotype.

1988 • 206 citations

A conserved CATTCCT motif is required for skeletal muscle-specific activity of the cardiac troponin T gene promoter.

1988 • 183 citations

Muscle-specific expression of the troponin I gene requires interactions between helix-loop-helix muscle regulatory factors and ubiquitous transcription factors.

1991 • 171 citations

The sarcomeric actin CArG-binding factor is indistinguishable from the c-fos serum response factor.

1989 • 166 citations

Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.

1991 • 159 citations

Differential trans activation associated with the muscle regulatory factors MyoD1, myogenin, and MRF4.

1990 • 157 citations

Upstream Regions of the Human Cardiac Actin Gene That Modulate Its Transcription in Muscle Cells: Presence of an Evolutionarily Conserved Repeated Motif

1986 • 155 citations

A New Myocyte-Specific Enhancer-Binding Factor That Recognizes a Conserved Element Associated with Multiple Muscle-Specific Genes

1989 • 154 citations

Activation of an intron enhancer within the keratin 18 gene by expression of c-fos and c-jun in undifferentiated F9 embryonal carcinoma cells.

1990 • 153 citations

Multiple 5'-flanking regions of the human alpha-skeletal actin gene synergistically modulate muscle-specific expression.

1987 • 150 citations

Activation of skeletal alpha-actin gene transcription: the cooperative formation of serum response factor-binding complexes over positive cis-acting promoter serum response elements displaces a negative-acting nuclear factor enriched in replicating myoblasts and nonmyogenic cells.

1991 • 143 citations

Effect of human T-cell leukemia virus type I tax protein on activation of the human vimentin gene

1990 • 124 citations

Characterization of the hamster desmin gene: Expression and formation of desmin filaments in nonmuscle cells after gene transfer

1985 • 112 citations

An internal regulatory element controls troponin I gene expression.

1989 • 103 citations

Identification of a Myocyte Nuclear Factor That Binds to the Muscle-Specific Enhancer of the Mouse Muscle Creatine Kinase Gene

1989 • 101 citations

Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes.

1989 • 97 citations

Isolation, Sequence, and Expression of a Human Keratin K5 Gene: Transcriptional Regulation of Keratins and Insights into Pairwise Control

1989 • 93 citations

AP-1/jun binding sites mediate serum inducibility of the human vimentin promoter

1989 • 87 citations

Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5′ end of the chicken α-skeletal actin gene

1986 • 86 citations

Identification of Upstream and Intragenic Regulatory Elements That Confer Cell-Type-Restricted and Differentiation-Specific Expression on the Muscle Creatine Kinase Gene

1988 • 86 citations

A developmental and tissue-specific enhancer in the mouse skeletal muscle acetylcholine receptor alpha-subunit gene regulated by myogenic factors.

1991 • 79 citations

High level desmin expression depends on a muscle-specific enhancer.

1991 • 73 citations

A cell type-specific enhancer drives expression of the chick muscle acetylcholine receptor α-subunit gene

1988 • 71 citations

Upstream regions of the hamster desmin and vimentin genes regulate expression during in vitro myogenesis.

1987 • 70 citations

Myogenin Induces the Myocyte-Specific Enhancer Binding Factor MEF-2 Independently of Other Muscle-Specific Gene Products

1991 • 67 citations

A Negative Element Involved in Vimentin Gene Expression

1990 • 64 citations

Characterization and regulation in the expression of a gene coding for the intermediate filament protein desmin.

1984 • 61 citations

Interaction of nuclear factors with the upstream region of the alpha-subunit gene of chicken muscle acetylcholine receptor: variations with muscle differentiation and denervation.

1989 • 59 citations

Expression of the acetylcholine receptor delta-subunit gene in differentiating chick muscle cells is activated by an element that contains two 16 bp copies of a segment of the alpha-subunit enhancer.

1990 • 51 citations

An Internal Regulatory Element Controls Troponin I Gene Expression

1989 • 48 citations

Muscle-Specific Expression of the Troponin I Gene Requires Interactions between Helix-Loop-Helix Muscle Regulatory Factors and Ubiquitous Transcription Factors

1991 • 48 citations

Muscle-specific gene expression controlled by a regulatory element lacking a MyoDl-binding site

1989 • 47 citations

The Sarcomeric Actin CArG-Binding Factor Is Indistinguishable from the c-fos Serum Response Factor

1989 • 47 citations

Multiple 5′-Flanking Regions of the Human α-Skeletal Actin Gene Synergistically Modulate Muscle-Specific Expression

1987 • 42 citations

Multiple elements are required for expression of an intermediate filament gene

1988 • 38 citations

Differential trans Activation Associated with the Muscle Regulatory Factors MyoD1, Myogenin, and MRF4

1990 • 34 citations

Activation of Skeletal α-Actin Gene Transcription: The Cooperative Formation of Serum Response Factor-Binding Complexes over Positive cis-Acting Promoter Serum Response Elements Displaces a Negative-Acting Nuclear Factor Enriched in Replicating Myoblasts and Nonmyogenic Cells

1991 • 28 citations